Search Results - "Sultanian, Richard a"

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    Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction by Dunham-Snary, Kimberly J, Wu, Danchen, Potus, François, Sykes, Edward A, Mewburn, Jeffrey D, Charles, Rebecca L, Eaton, Philip, Sultanian, Richard A, Archer, Stephen L

    Published in Circulation research (07-06-2019)
    “…RATIONALE:Hypoxic pulmonary vasoconstriction (HPV) optimizes systemic oxygen delivery by matching ventilation to perfusion. HPV is intrinsic to pulmonary…”
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    Journal Article
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    278 - Oxygen-sensing in the Lung is Regulated by Mitochondrial Complex I Ndufs2: Role of Mitochondria-derived Hydrogen Peroxide in Hypoxic Pulmonary Vasoconstriction by Dunham-Snary, Kimberly J, Wu, Danchen, Sykes, Edward A, Potus, François, Mewburn, Jeffrey D, Sultanian, Richard A, Archer, Stephen L

    Published in Free radical biology & medicine (01-11-2017)
    “…Resistance pulmonary arteries (PA) constrict in response to alveolar hypoxia; conversely the systemic vasculature dilates. Hypoxic pulmonary vasoconstriction…”
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    Abstract 14158: Ndufs2, the Rotenone-Binding Subunit of Mitochondrial Complex I, is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction by Dunham-Snary, Kimberly J, Wu, Danchen, Sykes, Edward A, Potus, François, Mewburn, Jeffrey D, Sultanian, Richard A, Archer, Stephen L

    Published in Circulation (New York, N.Y.) (06-11-2018)
    “…Background & AimsHypoxic pulmonary vasoconstriction (HPV) is intrinsic to smooth muscle cells from resistance pulmonary arteries (PA). HPV matches ventilation…”
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    Journal Article