Search Results - "Sulpice, J C"
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Flavonoid inhibition of platelet procoagulant activity and phosphoinositide synthesis
Published in Journal of thrombosis and haemostasis (01-08-2003)“…Dietary flavonoids are known for their antiplatelet activity resulting in cardiovascular protection. Phosphatidylinositol 4,5‐bisphosphate (PIP2) was…”
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Involvement of Phosphatidylinositol 4,5-Bisphosphate in Phosphatidylserine Exposure in Platelets: Use of a Permeant Phosphoinositide-Binding Peptide
Published in Biochemistry (Easton) (25-12-2001)“…During platelet activation, phosphatidylserine (PS) exposure on the extracellular face of the plasma membrane is associated with increased procoagulant…”
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Stretch-induced inositol trisphosphate and tetrakisphosphate production in rat cardiomyocytes
Published in Journal of molecular and cellular cardiology (01-08-1993)“…The kinetics and signal transduction of inositol phosphate production were studied after a 20% stretch of neonatal rat cardiomyocytes in culture. Inositol…”
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Asymmetric distribution of phosphoinositides and phosphatidic acid in the human erythrocyte membrane
Published in Biochimica et biophysica acta (14-10-1991)“…The distribution of phosphoinositides and phosphatidic acid (PA) between the outer and inner layers of the human erythrocyte membrane was investigated by using…”
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Functional heterogeneity of polyphosphoinositides in human erythrocytes
Published in Biochemical journal (01-12-1989)“…After labelling of erythrocytes with [32P]P1 for 23 h, the specific radioactivities of the phosphomonoester groups of PtdIns4P and of PtdIns(4,5)P2 approached…”
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Characterization of structural and functional phosphoinositide domains in human erythrocyte membranes
Published in Biochemistry (Easton) (15-06-1993)“…In the erythrocyte membrane, only a fraction (50-60%) of phosphatidylinositol 4,5-bisphosphate (PIP2) and of phosphatidylinositol 4-phosphate (PIP) is rapidly…”
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ATP-induced apoptosis of thymocytes is mediated by activation of P2X7 receptor and involves de novo ceramide synthesis and mitochondria
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (2006)“…Thymocytes were reported to undergo apoptosis in the presence of extracellular ATP through the activation of the purinergic receptors P2X1R, P2X7R or both. We…”
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Involvement of Sodium in Early Phosphatidylserine Exposure and Phospholipid Scrambling Induced by P2X7 Purinoceptor Activation in Thymocytes
Published in The Journal of biological chemistry (21-05-2004)“…Extracellular ATP (ATP ec ), a possible effector in thymocyte selection, induces thymocyte death via purinoceptor activation. We show that ATP ec induced cell…”
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Signaling pathways involved in glucocorticoid-induced apoptosis of thymocytes
Published in Critical Reviews in Immunology (2005)“…This review synthesizes recent insights on the signaling pathways triggered by glucocorticoids during apoptosis of thymocytes. Thymocyte apoptosis is a complex…”
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Requirement for phosphatidylinositol 4,5-bisphosphate in the Ca(2+)-induced phospholipid redistribution in the human erythrocyte membrane
Published in The Journal of biological chemistry (04-03-1994)“…In order to investigate how calcium on the cytosolic side of human erythrocytes induces the transmembrane redistribution of phospholipids, we studied the…”
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Squalene isolation by HPLC [High pressure liquid chromatography] and quantitative comparison by HPLC and GLC [Gas liquid chromatography, dietary fats]
Published in Lipids (01-08-1984)“…A new procedure is described for isolating and measuring squalene in plasma and in several organs of the rat. The unsaponifiable material was fractionated by…”
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Stimulation of polyphosphoinositide turnover upon activation of protein kinases in human erythrocytes
Published in Biochimica et biophysica acta (11-03-1988)“…Activation of protein kinase C in erythrocytes by 4-beta-phorbol 12-myristate 13-acetate (PMA) resulted in a parallel stimulation (time course and dose…”
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Calcium Induces Phospholipid Redistribution and Microvesicle Release in Human Erythrocyte Membranes by Independent Pathways
Published in Biochemistry (Easton) (03-11-1998)“…The increase in intracellular Ca2+ concentration in erythrocytes and platelets results in simultaneous phospholipid scrambling and microvesicle shedding…”
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Phosphatidylinositol 4,5-Bisphosphate Domain Inducers Promote Phospholipid Transverse Redistribution in Biological Membranes
Published in Biochemistry (Easton) (16-05-2000)“…Transmembrane phospholipid redistribution (scrambling), leading to exposure of phosphatidylserine on the cell surface, plays a physiological role to induce…”
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The separation of [32P]inositol phosphates by ion-pair chromatography: optimization of the method and biological applications
Published in Analytical biochemistry (15-05-1989)“…We have developed an ion-pair reverse-phase HPLC method to measure inositol phosphates in 32P-labeled cells. The different chromatographic parameters were…”
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Endogenous calcium in sickle cells does not activate polyphosphoinositide phospholipase C
Published in Biochemical journal (15-08-1988)“…Sickle-cell-anaemia erythrocytes (SS cells) are known to have a high Ca2+ content (particularly the dense cell fraction) and to take up Ca2+ on deoxygenation…”
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The effect of lanosterol on platelet aggregation in human platelets
Published in Thrombosis and haemostasis (17-12-1985)“…It has been reported that lanosterol can sensitize isolated rat platelets to agonists such as ADP and thrombin (4). The purpose of this paper was to determine…”
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Inositol phosphate production following α1-adrenergic, muscarinic or electrical stimulation in isolated rat heart
Published in FEBS letters (06-10-1986)“…A possible participation of polyphosphoinositide metabolism in the excitation-contraction coupling in heart was investigated. Isolated rat ventricles…”
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