Search Results - "Sulowska, Zofia"

Cholesterol oxidase is indispensable in the pathogenesis of Mycobacterium tuberculosis by Klink, Magdalena, Brzezinska, Marta, Szulc, Izabela, Brzostek, Anna, Kielbik, Michal, Sulowska, Zofia, Dziadek, Jaroslaw

“…Despite considerable research effort, the molecular mechanisms of Mycobacterium tuberculosis (Mtb) virulence remain unclear. Cholesterol oxidase (ChoD), an…”
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Either non-homologous ends joining or homologous recombination is required to repair double-strand breaks in the genome of macrophage-internalized Mycobacterium tuberculosis by Brzostek, Anna, Szulc, Izabela, Klink, Magdalena, Brzezinska, Marta, Sulowska, Zofia, Dziadek, Jaroslaw

“…The intracellular pathogen Mycobacterium tuberculosis (Mtb) is constantly exposed to a multitude of hostile conditions and is confronted by a variety of…”
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Seasonal changes in activities of human neutrophils in vitro by Klink, Magdalena, Bednarska, Katarzyna, Blus, Edyta, Kielbik, Michal, Sulowska, Zofia

“…Objective and design We present a retrospective analysis of previously collected blood samples to determine whether the immune response of neutrophils depends…”
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Nitric oxide donors reduce the invasion ability of ovarian cancer cells in vitro by Kielbik, Michal, Szulc, Izabela, Brzezinska, Marta, Bednarska, Katarzyna, Przygodzka, Patrycja, Sulowska, Zofia, Nowak, Marek, Klink, Magdalena

“…The most important factors involved in tumor metastasis and angiogenesis are metalloproteinases (MMPs), vascular endothelial growth factor, and multifunctional…”
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Cholesterol Oxidase Binds TLR2 and Modulates Functional Responses of Human Macrophages by Dziadek, Jaroslaw, Sulowska, Zofia, Kielbik, Michal, Bednarska, Katarzyna, Klink, Magdalena

“…Cholesterol oxidase (ChoD) is considered to be an important virulence factor for Mycobacterium tuberculosis (Mtb), but its influence on macrophage activity is…”
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Adenosine and 2′-Deoxyadenosine Modified with Boron Cluster Pharmacophores as New Classes of Human Blood Platelet Function Modulators by Bednarska, Katarzyna, Olejniczak, Agnieszka B., Wojtczak, Błażej A., Sułowska, Zofia, Leśnikowski, Zbigniew J.

“…Novel types of adenosine and 2′‐deoxyadenosine derivatives containing boron clusters at positions C2′, N6, or C8 were synthesized. The effect of these modified…”
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Antitumoral Activity Of Nitric Oxide-Releasing Compounds by Klink, Magdalena, Kielbik, Michal, Kielbik, Izabela Szulc, Przygodzka, Patrycja, Sulowska, Zofia

“…Despite significant improvements in the conventional anti-ovarian cancer therapies, tumor cell resistance to various cytostatic drugs remains a relevant…”
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Effect of nitric oxide donors on NADPH oxidase signaling pathway in human neutrophils in vitro by Klink, Magdalena, Jastrzembska, Katarzyna, Bednarska, Katarzyna, Banasik, Małgorzata, Sulowska, Zofia

“…Abstract The production of reactive oxygen species (ROS) in activated neutrophils is catalyzed by NADPH oxidase, a multiproteins complex. Various protein…”
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Application of Intracellular Alkaline Phosphatase Activity Measurement in Detection of Neutrophil Adherence In Vitro by BEDNARSKA, Katarzyna, KLINK, Magdalena, SULOWSKA, Zofia

“…We have proposed the use of the fluorimetric method with 4-methylumbelliferyl phosphate (4-MUP) specific substrate for the alkaline phosphatase determination…”
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Analysis of preoperative blood platelet parameters in terms of diversity of epithelial ovarian cancer by Bednarska, Katarzyna, Król, Ewa, Głowacka, Ewa, Romanowicz, Hanna, Szyłło, Krzysztof, Klink, Magdalena, Sułowska, Zofia, Nowak, Marek

“…Smouldering inflammation, thrombocytosis, and platelet hyper-reactivity are linked to malignancy. The relationships between preoperative diagnostic blood…”
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Flow Cytometric Evaluation of Human Neutrophil Apoptosis During Nitric Oxide Generation In Vitro: The Role of Exogenous Antioxidants by Sulowska, Zofia, Majewska, Ewa, Klink, Magdalena, Banasik, Malgorzata, Tchórzewski, Henryk

“…Among numerous inflammatory mediators a nitric oxide molecule is supposed to be important in the modulation of neutrophil survival in vivo and in vitro. The…”
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Modulation of human neutrophil activity by adenosine modified with a carborane pharmacophore by Bednarska, Katarzyna, Olejniczak, Agnieszka B., Klink, Magdalena, Sułowska, Zofia, Leśnikowski, Zbigniew J.

“…An impact of adenosine modification with electroneutral, lipophilic 1,12-dicarba-closo-dodecaborane or electronegative 7,8-dicarba-nido-undecaborane boron…”
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Involvement of nitric oxide donor compounds in the bactericidal activity of human neutrophils in vitro by Klink, Magdalena, Cedzynski, Maciej, St Swierzko, Anna, Tchorzewski, Henryk, Sulowska, Zofia

“…1 Microbiology and Virology Centre, Polish Academy of Sciences, 93-232 Lodz, Lodowa 106, Poland 2 Department of Clinical Immunology, Institute of Polish…”
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Oxidative and adhesive responses of human neutrophils to nitrovasodilators in vitro: the role of protein kinases by Klink, Magdalena, Tchorzewski, Henryk, Sulowska, Zofia

“…Background: Sodium nitroprusside (SNP) and molsidomine are used in the treatment of coronary heart disease. Since the neutrophils play a pathological role in…”
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Heterogeneity of the Mac-1 expression on peripheral blood neutrophils in patients with different types of epithelial ovarian cancer by Bednarska, Katarzyna, Klink, Magdalena, Wilczyński, Jacek R, Szyłło, Krzysztof, Malinowski, Andrzej, Sułowska, Zofia, Nowak, Marek

“…Abstract The expression level of Mac-1 on the surface of neutrophils is an important indicator of neutrophil activation. Under pathological conditions, Mac-1…”
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Nitric oxide donors: Spermine/NO and diethylenetriamine/NO induce ovarian cancer cell death and affect STAT3 and AKT signaling proteins by Kielbik, Michal, Klink, Magdalena, Brzezinska, Marta, Szulc, Izabela, Sulowska, Zofia

“…•SPER/NO and DETA/NO presented cytotoxic activity against ovarian cancer cell lines.•Cytotoxicity was mainly based on the induction of apoptosis.•NO donors…”
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Influence of opioid peptides on human neutrophil apoptosis and activation in vitro by Sulowska, Zofia, Majewska, Ewa, Krawczyk, Katarzyna, Klink, Magdalena, Tchórzewski, Henryk

“…BACKGROUND: It has been shown that cells of the immune system release opioid peptides and possess receptors for them. The concentrations of opioid peptides in…”
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Secretion of cytokines and heat shock protein (HspA1A) by ovarian cancer cells depending on the tumor type and stage of disease by Nowak, Marek, Glowacka, Ewa, Kielbik, Michal, Kulig, Andrzej, Sulowska, Zofia, Klink, Magdalena

“…•Type II ovarian cancer cells secrete high amount of immunosuppressive factors.•Type II ovarian cancer cells have greater predisposition toward immune…”
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Evaluation of nitric oxide donors impact on cisplatin resistance in various ovarian cancer cell lines by Kielbik, Michal, Szulc-Kielbik, Izabela, Nowak, Marek, Sulowska, Zofia, Klink, Magdalena

“…Ovarian cancer chemoresistance, both intrinsic and acquired, is the main obstacle in improving the outcome of anticancer therapies. Therefore the development…”
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The role of 3-ketosteroid 1(2)-dehydrogenase in the pathogenicity of Mycobacterium tuberculosis by Brzezinska, Marta, Szulc, Izabela, Brzostek, Anna, Klink, Magdalena, Kielbik, Michal, Sulowska, Zofia, Pawelczyk, Jakub, Dziadek, Jaroslaw

“…A growing body of evidence suggests that Mycobacterium tuberculosis (Mtb) uses the host's cholesterol as a source of carbon and energy during infection…”
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