Search Results - "Sullivan, Sarah M"

Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection by Sullivan, Sarah M, Holyoak, Todd

“…The induced fit and conformational selection/population shift models are two extreme cases of a continuum aimed at understanding the mechanism by which the…”
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Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS by Vassall, Kenrick A., Stubbs, Helen R., Primmer, Heather A., Tong, Ming Sze, Sullivan, Sarah M., Sobering, Ryan, Srinivasan, Saipraveen, Briere, Lee-Ann K., Dunn, Stanley D., Colón, Wilfredo, Meiering, Elizabeth M., Fersht, Alan R.

“…Protein aggregation is a hallmark of many diseases, including amyotrophic lateral sclerosis (ALS), where aggregation of Cu/Zn superoxide dismutase (SOD1) is…”
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Adherence to Hygiene Protocols and Doxycycline Therapy in Ameliorating Lymphatic Filariasis Morbidity in an Endemic Area Post-Interruption of Disease Transmission in Ghana by Debrah, Linda Batsa, Klarmann-Schulz, Ute, Osei-Mensah, Jubin, Kuehlwein, Janina M, Mubarik, Yusif, Nadal, Jennifer, Ayisi-Boateng, Nana Kwame, Ricchiuto, Arcangelo, Opoku, Vera Serwaa, Sullivan, Sarah M, Mensah, Derrick Adu, Horton, John, Rahamani, Abu Abudu, Budge, Philip J, Gbedema, Stephen, Korir, Patricia Jebett, Opoku, John, Pfarr, Kenneth, Kontoh, Derrick Boateng, Kellings, Angelika, Gyasi, Charles, Obeng, Michael Agyemang, Gruetzmacher, Barbara, Fordjour, Fatima Amponsah, Kroidl, Inge, Horn, Sacha, Kuutiero, Eunice Kyaakyile, Wauschkuhn, Caroline, Ngenya, Abdallah, Mackenzie, Charles, Wanji, Samuel, Kalinga, Akili, Ottesen, Eric A, Hoerauf, Achim, Debrah, Alexander Yaw

“…Filarial lymphedema (LE) remains a significant global problem despite the progress made toward elimination of lymphatic filariasis (LF). In Ghana, the main…”
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Structures of Rat Cytosolic PEPCK:  Insight into the Mechanism of Phosphorylation and Decarboxylation of Oxaloacetic Acid by Sullivan, Sarah M, Holyoak, Todd

“…The structures of the rat cytosolic isoform of phosphoenolpyruvate carboxykinase (PEPCK) reported in the PEPCK-Mn2+, -Mn2+-oxaloacetic acid (OAA),…”
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Structural Insights into the Mechanism of PEPCK Catalysis by Holyoak, Todd, Sullivan, Sarah M, Nowak, Thomas

“…Phosphoenolpyruvate carboxykinase catalyzes the reversible decarboxylation of oxaloacetic acid with the concomitant transfer of the γ-phosphate of GTP to form…”
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Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition by Stiffin, Rose Mary, Sullivan, Sarah M., Carlson, Gerald M., Holyoak, Todd

“…The mechanisms of molecular recognition of phosphoenolpyruvate (PEP) and oxaloacetate (OAA) by cytosolic phosphoenolpyruvate carboxykinase (cPEPCK) were…”
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Patterns of response to patient-centered decision support through a personal health record by Hess, Rachel, Fischer, Gary S, Sullivan, Sarah M, Dong, XinXin, Weimer, Melissa, Zeith, Caroline, Clark, Sunday, Roberts, Mark S

“…Over 140 million people in the United States have at least one chronic medical condition, but they receive fewer than 60% of guideline-recommended services for…”
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Abstract 213: Engaging Cardiology Patients Via Electronic Patient-Reported Outcomes: A Usability Assessment by Kavalieratos, Dio, Sullivan, Sarah M, Hess, Rachel

“…Abstract only Background: The use of electronic patient-reported outcomes (ePROs) in clinical practice is a powerful method of engaging the patient voice to…”
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1H-filtered correlation experiments for assignment and determination of coupling constants in backbone labelled proteins by Giesen, Alexander W, Bae, Lynnette C, Barrett, Christa L, Chyba, Jason A, Chaykovsky, Michael M, Cheng, Minn-Chang, Murray, Jenny H, Oliver, Ed J, Sullivan, Sarah M, Brown, Jonathan Miles, Homans, Steve W

“…The implementation of [13Calpha,13C',15N,2Halpha] labelled amino acids into proteins allows the acquisition of high resolution triple resonance experiments. We…”
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Measurement of one-bond 1H-13C, couplings in backbone-labelled proteins by Giesen, A W, Bae, L C, Barrett, C L, Chyba, J A, Chaykovsky, M M, Cheng, M C, Murray, J H, Oliver, E J, Sullivan, S M, Brown, J M, Dahlquist, F W, Homans, S W

“…NMR dipole-dipole couplings between protein backbone nuclei (1H(alpha), 13C(alpha), 15N, 1H(N), 13C') offer enormous scope for the rapid determination of…”
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