Search Results - "Sullivan, K."
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Excitatory connections between the prelimbic and infralimbic medial prefrontal cortex show a role for the prelimbic cortex in fear extinction
Published in Nature neuroscience (01-05-2018)“…We elucidated the intrinsic circuitry of the medial prefrontal cortex and its role in regulating fear extinction, using neuronal tracing and optogenetic…”
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2
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters
Published in Nature communications (17-11-2022)“…Chemotherapy can eradicate a majority of cancer cells. However, a small population of tumor cells often survives drug treatments through genetic and/or…”
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3
Functional properties and projections of neurons in the medial amygdala
Published in The Journal of neuroscience (25-06-2014)“…The medial nucleus of the amygdala (MeA) plays a key role in innate emotional behaviors by relaying olfactory information to hypothalamic nuclei involved in…”
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4
Is incident rheumatoid arthritis interstitial lung disease associated with methotrexate treatment? Results from a multivariate analysis in the ERAS and ERAN inception cohorts
Published in BMJ open (01-05-2019)“…ObjectivesTo assess predictive factors for rheumatoid arthritis interstitial lung disease (RA-ILD) in two early rheumatoid arthritis (RA) inception cohorts…”
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Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab
Published in Nature reviews. Drug discovery (01-05-2012)“…Key Points This Review chronicles the events that led to an increased understanding of osteoclast biology, the identification of osteoprotegerin (OPG) and the…”
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Ultrasensitive, rapid and inexpensive detection of DNA using paper based lateral flow assay
Published in Scientific reports (25-11-2016)“…Sensitive, specific, rapid, inexpensive and easy-to-use nucleic acid tests for use at the point-of-need are critical for the emerging field of personalised…”
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Global patterns of the species richness and distribution of eriophyoid mites: a response to Li et al. 2023
Published in Journal of biogeography (01-01-2024)“…Aim The global distribution and diversity of mites, including the species rich and highly host plant‐specific eriophyoid mites, are important questions in…”
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Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis
Published in Nature genetics (01-12-2015)“…Po-Ru Loh, Alkes Price and colleagues developed a fast algorithm for multicomponent, multi-trait variance-components analysis and use it to analyze the genetic…”
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Toward an Information Infrastructure for Global Health Improvement
Published in Yearbook of medical informatics (01-08-2017)“…Profound global challenges to individual and population health, alongside the opportunities to benefit from digital technology, have spawned the concept of the…”
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UK national guidelines on the management of syphilis 2015
Published in International journal of STD & AIDS (01-05-2016)“…These guidelines are an update for 2015 of the 2008 UK guidelines for the management of syphilis. The writing group have piloted the new BASHH guideline…”
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Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial
Published in The Lancet (British edition) (02-01-2016)“…Summary Background Randomised placebo-controlled trials have shown that daily oral pre-exposure prophylaxis (PrEP) with tenofovir–emtricitabine reduces the…”
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Evidence-based guideline update: Treatment of essential tremor: Report of the Quality Standards Subcommittee of the American Academy of Neurology
Published in Neurology (08-11-2011)“…This evidence-based guideline is an update of the 2005 American Academy of Neurology practice parameter on the treatment of essential tremor (ET). A literature…”
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13
Hypoxia as a barrier to immunotherapy in pancreatic adenocarcinoma
Published in Clinical and translational medicine (01-04-2019)“…Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with limited response to cytotoxic chemoradiotherapy, as well as newer immunotherapies. The PDA…”
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14
Biocompatible Soft Fluidic Strain and Force Sensors for Wearable Devices
Published in Advanced functional materials (14-02-2019)“…Fluidic soft sensors have been widely used in wearable devices for human motion capturing. However, thus far, the biocompatibility of the conductive liquid,…”
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Hybrid Antibody–Aptamer Assay for Detection of Tetrodotoxin in Pufferfish
Published in Analytical chemistry (Washington) (09-11-2021)“…The marine toxin tetrodotoxin (TTX) poses a great risk to public health safety due to its severe paralytic effects after ingestion. Seafood poisoning caused by…”
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Practice Parameter: Treatment of nonmotor symptoms of Parkinson disease: Report of the Quality Standards Subcommittee of the American Academy of Neurology
Published in Neurology (16-03-2010)“…Nonmotor symptoms (sleep dysfunction, sensory symptoms, autonomic dysfunction, mood disorders, and cognitive abnormalities) in Parkinson disease (PD) are a…”
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Pharmacological Inhibition and Activation of the Ca2+ Activated Cl− Channel TMEM16A
Published in International journal of molecular sciences (07-04-2020)“…TMEM16A is a Ca2+ activated Cl− channel with important functions in airways, intestine, and other epithelial organs. Activation of TMEM16A is proposed as a…”
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Mortality and causes of death in people diagnosed with HIV in the era of highly active antiretroviral therapy compared with the general population: an analysis of a national observational cohort
Published in The Lancet. Public health (01-01-2017)“…Deaths in HIV-positive people have decreased since the introduction of highly active antiretroviral therapy (HAART) in 1996. Fewer AIDS-related deaths and an…”
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Alarming evidence of widespread mite extinctions in the shadows of plant, insect and vertebrate extinctions
Published in Austral ecology (01-02-2021)“…This paper, which addresses the issue of the extinction of mite species at the global scale for the first time, highlights mite diversity, assesses the…”
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NHANES 2011-2014 Reveals Cognition of US Older Adults may Benefit from Better Adaptation to the Mediterranean Diet
Published in Nutrients (29-06-2020)“…Although the Mediterranean diet (MedD) has gained interest for potential Alzheimer's disease (AD) prevention, it is unknown how well US older adults follow a…”
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