Search Results - "Sullivan, Gemma"
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General factors of white matter microstructure from DTI and NODDI in the developing brain
Published in NeuroImage (Orlando, Fla.) (01-07-2022)“…Preterm birth is closely associated with diffuse white matter dysmaturation inferred from diffusion MRI and neurocognitive impairment in childhood. Diffusion…”
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Neonatal morphometric similarity mapping for predicting brain age and characterizing neuroanatomic variation associated with preterm birth
Published in NeuroImage clinical (01-01-2020)“…•Multiple MRI features are integrated in a single model to study brain maturation in newborns.•Morphometric similarity networks (MSNs) provide a whole-brain…”
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Maternal cortisol is associated with neonatal amygdala microstructure and connectivity in a sexually dimorphic manner
Published in eLife (24-11-2020)“…The mechanisms linking maternal stress in pregnancy with infant neurodevelopment in a sexually dimorphic manner are poorly understood. We tested the hypothesis…”
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Preterm Birth Is Associated With Immune Dysregulation Which Persists in Infants Exposed to Histologic Chorioamnionitis
Published in Frontiers in immunology (27-08-2021)“…Preterm infants are at increased risk of exposure to histologic chorioamnionitis (HCA) when compared to term-born controls, and this is associated with several…”
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The Cerebrospinal Fluid Inflammatory Response to Preterm Birth
Published in Frontiers in physiology (12-09-2018)“…Preterm birth is the leading risk factor for perinatal white matter injury, which can lead to motor and neuropsychiatric impairment across the life course…”
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Epigenetic scores derived in saliva are associated with gestational age at birth
Published in Clinical epigenetics (29-06-2024)“…Epigenetic scores (EpiScores), reflecting DNA methylation (DNAm)-based surrogates for complex traits, have been developed for multiple circulating proteins…”
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Peak Width of Skeletonized Water Diffusion MRI in the Neonatal Brain
Published in Frontiers in neurology (03-04-2020)“…Preterm birth is closely associated with cognitive impairment and generalized dysconnectivity of neural networks inferred from water diffusion MRI (dMRI)…”
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Early breast milk exposure modifies brain connectivity in preterm infants
Published in NeuroImage (Orlando, Fla.) (01-01-2019)“…Preterm infants are at increased risk of alterations in brain structure and connectivity, and subsequent neurocognitive impairment. Breast milk may be more…”
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Breast Milk Exposure is Associated With Cortical Maturation in Preterm Infants
Published in Annals of neurology (01-03-2023)“…Objective Breast milk exposure is associated with improved neurocognitive outcomes following preterm birth but the neural substrates linking breast milk with…”
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Microglial inflammasome activation drives developmental white matter injury
Published in Glia (01-05-2021)“…Injury to the developing brain during the perinatal period often causes hypomyelination, leading to clinical deficits for which there is an unmet therapeutic…”
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Hierarchical Complexity of the Macro-Scale Neonatal Brain
Published in Cerebral cortex (New York, N.Y. 1991) (05-03-2021)“…Abstract The human adult structural connectome has a rich nodal hierarchy, with highly diverse connectivity patterns aligned to the diverse range of functional…”
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Language function following preterm birth: prediction using machine learning
Published in Pediatric research (01-08-2022)“…Background Preterm birth can lead to impaired language development. This study aimed to predict language outcomes at 2 years corrected gestational age (CGA)…”
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Interleukin-8 dysregulation is implicated in brain dysmaturation following preterm birth
Published in Brain, behavior, and immunity (01-11-2020)“…•Elevated IL-8 is a characteristic feature of intrauterine inflammation in the context of preterm birth.•IL-8 concentration is associated with neurite density…”
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Immuno-epigenetic signature derived in saliva associates with the encephalopathy of prematurity and perinatal inflammatory disorders
Published in Brain, behavior, and immunity (01-05-2023)“…[Display omitted] •DNA methylation signature of inflammation derived in neonatal saliva samples.•Preterm infants display higher inflammatory-related DNAm than…”
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Perinatal determinants of neonatal hair glucocorticoid concentrations
Published in Psychoneuroendocrinology (01-06-2021)“…Adult hair glucocorticoid concentrations reflect months of hypothalamic-pituitary-adrenal axis activity. However, little is known about the determinants of…”
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Emotion regulation and cortisol response to the still-face procedure in preterm and full-term infants
Published in Psychoneuroendocrinology (01-07-2022)“…In infancy, stress responses and emotion regulation are often coupled. Both are impacted by prematurity, though their relationship to one another in the case…”
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Saliva cortisol diurnal variation and stress responses in term and preterm infants
Published in Archives of disease in childhood. Fetal and neonatal edition (01-09-2022)“…To determine if preterm birth is associated with adaptation of the hypothalamic-pituitary-adrenal (HPA) axis and whether HPA axis programming relates to the…”
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Feature similarity gradients detect alterations in the neonatal cortex associated with preterm birth
Published in Human brain mapping (01-03-2024)“…The early life environment programmes cortical architecture and cognition across the life course. A measure of cortical organisation that integrates…”
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Preterm infant attachment is independent of breast milk intake during neonatal care
Published in Wellcome open research (2024)“…Background Following preterm birth, breast milk feeding is recommended because it confers broad health benefits to preterm infants. Breast milk has been…”
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Preterm birth and infant diurnal cortisol regulation
Published in Archives of disease in childhood. Fetal and neonatal edition (01-09-2022)“…Hypothalamic-pituitary-adrenal (HPA) axis adaptation is a potential mechanism linking early life exposures with later adverse health. This study tested the…”
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