Search Results - "Sullivan, Carol M."

Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: Evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors by LOKKER, Nathalie A, SULLIVAN, Carol M, HOLLENBACH, Stanley J, ISRAEL, Mark A, GIESE, Neill A

“…Glioblastoma multiforme, the most common form of malignant brain tumor,is resistant to all forms of therapy and causes death within 9-12 months of diagnosis…”
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CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML) by Kelly, Louise M, Yu, Jin-Chen, Boulton, Christina L, Apatira, Mutiah, Li, Jason, Sullivan, Carol M, Williams, Ifor, Amaral, Sonia M, Curley, David P, Duclos, Nicole, Neuberg, Donna, Scarborough, Robert M, Pandey, Anjali, Hollenbach, Stanley, Abe, Keith, Lokker, Nathalie A, Gilliland, D.Gary, Giese, Neill A

“…Up to 30% of acute myelogenous leukemia (AML) patients harbor an activating internal tandem duplication (ITD) within the juxtamembrane domain of the FLT3…”
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PDGF C Is A Selective α Platelet-Derived Growth Factor Receptor Agonist That Is Highly Expressed in Platelet α Granules and Vascular Smooth Muscle by Fang, Li, Yan, Yibing, Komuves, Laszlo G, Yonkovich, Shirlee, Sullivan, Carol M, Stringer, Bradley, Galbraith, Sarah, Lokker, Nathalie A, Hwang, S Stuart, Nurden, Paquita, Phillips, David R, Giese, Neill A

“…OBJECTIVE—The platelet-derived growth factor (PDGF) family consists of four members, PDGF A, PDGF B, and 2 new members, PDGF C and PDGF D, which signal through…”
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Biochemical and Cellular Characterization of the Novel Proteasome Inhibitor PR-171 by Demo, Susan D., Buchholz, Tonia J., Laidig, Guy J., Parlati, Francesco, Shenk, Kevin D., Smyth, Mark S., Sullivan, Carol M., Sun, Congcong M., Vallone, Marcy K., Woo, Tina, Bennett, Mark K.

“…Recent clinical studies have identified the proteasome as an important therapeutic target for hematologic malignances. The proteasome inhibitor, bortezomib,…”
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