Search Results - "Sullivan, Aaron B"
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Maresin 1 Promotes Inflammatory Resolution, Neuroprotection, and Functional Neurological Recovery After Spinal Cord Injury
Published in The Journal of neuroscience (29-11-2017)“…Resolution of inflammation is defective after spinal cord injury (SCI), which impairs tissue integrity and remodeling and leads to functional deficits…”
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Proresolution lipid mediators in multiple sclerosis - differential, disease severity-dependent synthesis - a clinical pilot trial
Published in PloS one (08-02-2013)“…The severity and longevity of inflammation is controlled by endogenous counter-regulatory signals. Among them are long-chain polyunsaturated fatty acid…”
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IL-1R and MyD88 Contribute to the Absence of a Bacterial Microbiome on the Healthy Murine Cornea
Published in Frontiers in microbiology (29-05-2018)“…Microbial communities are important for the health of mucosal tissues. Traditional culture and gene sequencing have demonstrated bacterial populations on the…”
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Endogenous LXA4 Circuits Are Determinants of Pathological Angiogenesis in Response to Chronic Injury
Published in The American journal of pathology (2010)“…Inflammation and angiogenesis are intimately linked, and their dysregulation leads to pathological angiogenesis in human diseases. 15-lipoxygenase (15-LOX) and…”
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The importance of the Pseudomonas aeruginosa type III secretion system in epithelium traversal depends upon conditions of host susceptibility
Published in Infection and immunity (01-04-2015)“…Pseudomonas aeruginosa is invasive or cytotoxic to host cells, depending on the type III secretion system (T3SS) effectors encoded. While the T3SS is known to…”
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A novel murine model for contact lens wear reveals clandestine IL-1R dependent corneal parainflammation and susceptibility to microbial keratitis upon inoculation with Pseudomonas aeruginosa
Published in The ocular surface (01-01-2019)“…Contact lens wear carries a risk of complications, including corneal infection. Solving these complications has been hindered by limitations of existing animal…”
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Traversal of multilayered corneal epithelia by cytotoxic Pseudomonas aeruginosa requires the phospholipase domain of exoU
Published in Investigative ophthalmology & visual science (25-01-2012)“…Pseudomonas aeruginosa isolates from microbial keratitis are invasive or cytotoxic toward mammalian cells, depending on their type III secreted toxins…”
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Selective activation of the prostaglandin E2 circuit in chronic injury-induced pathologic angiogenesis
Published in Investigative ophthalmology & visual science (01-12-2010)“…Cyclooxygenase (COX)-derived prostaglandin E(2) (PGE(2)) is a prevalent and established mediator of inflammation and pain in numerous tissues and diseases…”
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Colchicine attenuates compensation to negative but not to positive lenses in young chicks
Published in Experimental eye research (01-02-2008)“…Optic nerve-sectioned (ONS) chick eyes are capable of emmetropisation, but these eyes also exhibit increased hyperopia without any visual manipulations, which…”
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Selective Activation of the Prostaglandin E 2 Circuit in Chronic Injury-Induced Pathologic Angiogenesis
Published in Investigative ophthalmology & visual science (01-12-2010)Get full text
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Endogenous LXA 4 Circuits Are Determinants of Pathological Angiogenesis in Response to Chronic Injury
Published in The American journal of pathology (2010)“…Inflammation and angiogenesis are intimately linked, and their dysregulation leads to pathological angiogenesis in human diseases. 15-lipoxygenase (15-LOX) and…”
Get full text
Journal Article