Effectiveness of Anise Oil for Treatment of Mild to Moderate Depression in Patients With Irritable Bowel Syndrome

Depression is a prevalent disorder among patients suffering from irritable bowel syndrome. The current study was performed to evaluate the effect of a traditional Persian medicine product, anise oil, in removing the symptoms of mild to moderate depression in patients with irritable bowel syndrome. I...

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Bibliographic Details
Published in:	Journal of evidence-based complementary & alternative medicine Vol. 22
Main Authors:	Maryam Mosaffa-Jahromi PharmD, PhD, Ali-Mohammad Tamaddon PharmD, PhD, Suleiman Afsharypuor PharmD, PhD, Alireza Salehi MD, MPH, PhD, Seyed Hassan Seradj PharmD, PhD, Mehdi Pasalar MD, MPH, PhD, Peyman Jafari PhD, Kamran Bagheri Lankarani MD
Format:	Journal Article
Language:	English
Published:	SAGE Publishing 01-01-2017
Online Access:	Get full text
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Summary:	Depression is a prevalent disorder among patients suffering from irritable bowel syndrome. The current study was performed to evaluate the effect of a traditional Persian medicine product, anise oil, in removing the symptoms of mild to moderate depression in patients with irritable bowel syndrome. In a randomized double-blinded active and placebo controlled clinical trial, 120 participants with mild to moderate depression according to the Beck Depression Inventory–II total scores were categorized into 3 equal groups and received anise oil, Colpermin, and placebo. The results at the end of trial (week 4) and follow-up (week 6) demonstrated significant priority against active and placebo groups. Although the mechanism is unknown yet, anise oil could be a promising choice of treatment for depressed patients with irritable bowel syndrome.
ISSN:	2156-5872 2156-5899
DOI:	10.1177/2156587216628374