Search Results - "Sulchek, Todd A"

Porous PEEK improves the bone-implant interface compared to plasma-sprayed titanium coating on PEEK by Torstrick, F. Brennan, Lin, Angela S.P., Potter, Daniel, Safranski, David L., Sulchek, Todd A., Gall, Ken, Guldberg, Robert E.

“…Polyether-ether-ketone (PEEK) is one of the most common materials used for load-bearing orthopaedic devices due to its radiolucency and favorable mechanical…”
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Nuclear Membrane-Targeted Gold Nanoparticles Inhibit Cancer Cell Migration and Invasion by Ali, Moustafa R. K, Wu, Yue, Ghosh, Deepraj, Do, Brian H, Chen, Kuangcai, Dawson, Michelle R, Fang, Ning, Sulchek, Todd A, El-Sayed, Mostafa A

“…Most cancer patients die from metastasis. Recent studies have shown that gold nanoparticles (AuNPs) can slow down the migration/invasion speed of cancer cells…”
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Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis-associated epithelial-to-mesenchymal transitions by Brown, Ashley C, Fiore, Vincent F, Sulchek, Todd A, Barker, Thomas H

“…Increased tissue stiffness and epithelial‐to‐mesenchymal transitions (EMTs) are two seemingly discrete hallmarks of fibrotic diseases. Despite recent findings…”
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Cellular softening mediates leukocyte demargination and trafficking, thereby increasing clinical blood counts by Fay, Meredith E., Myers, David R., Kumar, Amit, Turbyfield, Cory T., Byler, Rebecca, Crawford, Kaci, Mannino, Robert G., Laohapant, Alvin, Tyburski, Erika A., Sakurai, Yumiko, Rosenbluth, Michael J., Switz, Neil A., Sulchek, Todd A., Graham, Michael D., Lam, Wilbur A.

“…Leukocytes normally marginate toward the vascular wall in large vessels and within the microvasculature. Reversal of this process, leukocyte demargination,…”
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Maleimide Cross-Linked Bioactive PEG Hydrogel Exhibits Improved Reaction Kinetics and Cross-Linking for Cell Encapsulation and In Situ Delivery by Phelps, Edward A., Enemchukwu, Nduka O., Fiore, Vincent F., Sy, Jay C., Murthy, Niren, Sulchek, Todd A., Barker, Thomas H., García, Andrés J.

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Pathologic mechanobiological interactions between red blood cells and endothelial cells directly induce vasculopathy in iron deficiency anemia by Caruso, Christina, Fay, Meredith E., Cheng, Xiaopo, Liu, Alan Y., Park, Sunita I., Sulchek, Todd A., Graham, Michael D., Lam, Wilbur A.

“…The correlation between cardiovascular disease and iron deficiency anemia (IDA) is well documented but poorly understood. Using a multi-disciplinary approach,…”
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Dynamic Force Spectroscopy of Parallel Individual Mucin1-Antibody Bonds by Todd A. Sulchek, Raymond W. Friddle, Kevin Langry, Lau, Edmond Y., Huguette Albrecht, Timothy V. Ratto, DeNardo, Sally J., Colvin, Michael E., Noy, Aleksandr

“…We used atomic force microscopy to measure the binding forces between Mucini (MUC1) peptide and a single-chain variable fragment (scFv) antibody selected from…”
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Cell-free Co-expression of Functional Membrane Proteins and Apolipoprotein, Forming Soluble Nanolipoprotein Particles by Cappuccio, Jenny A., Blanchette, Craig D., Sulchek, Todd A., Arroyo, Erin S., Kralj, Joel M., Hinz, Angela K., Kuhn, Edward A., Chromy, Brett A., Segelke, Brent W., Rothschild, Kenneth J., Fletcher, Julia E., Katzen, Federico, Peterson, Todd C., Kudlicki, Wieslaw A., Bench, Graham, Hoeprich, Paul D., Coleman, Matthew A.

“…Here we demonstrate rapid production of solubilized and functional membrane protein by simultaneous cell-free expression of an apolipoprotein and a membrane…”
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Different Apolipoproteins Impact Nanolipoprotein Particle Formation by Chromy, Brett A, Arroyo, Erin, Blanchette, Craig D, Bench, Graham, Benner, Henry, Cappuccio, Jenny A, Coleman, Matthew A, Henderson, Paul T, Hinz, Angie K, Kuhn, Edward A, Pesavento, Joseph B, Segelke, Brent W, Sulchek, Todd A, Tarasow, Ted, Walsworth, Vicki L, Hoeprich, Paul D

“…Spontaneous interaction of purified apolipoproteins and phospholipids results in formation of lipoprotein particles with nanometer-sized dimensions; we refer…”
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Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss by San Emeterio, Cheryl L, Hymel, Lauren A, Turner, Thomas C, Ogle, Molly E, Pendleton, Emily G, York, William Y, Olingy, Claire E, Liu, Alan Y, Lim, Hong Seo, Sulchek, Todd A, Warren, Gordon L, Mortensen, Luke J, Qiu, Peng, Jang, Young C, Willett, Nick J, Botchwey, Edward A

“…Volumetric muscle loss (VML) injuries after extremity trauma results in an important clinical challenge often associated with impaired healing, significant…”
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Decoupling internalization, acidification and phagosomal-endosomal/lysosomal fusion during phagocytosis of InlA coated beads in epithelial cells by Blanchette, Craig D, Woo, Youn-Hi, Thomas, Cynthia, Shen, Nan, Sulchek, Todd A, Hiddessen, Amy L

“…Phagocytosis has been extensively examined in 'professional' phagocytic cells using pH sensitive dyes. However, in many of the previous studies, a separation…”
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Biomechanics of Endothelial Tubule Formation Differentially Modulated by Cerebral Cavernous Malformation Proteins by Chernaya, Olga, Zhurikhina, Anastasia, Hladyshau, Siarhei, Pilcher, William, Young, Katherine M, Ortner, Jillian, Andra, Vaishnavi, Sulchek, Todd A, Tsygankov, Denis

“…At early stages of organismal development, endothelial cells self-organize into complex networks subsequently giving rise to mature blood vessels. The…”
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Quantifying size distributions of nanolipoprotein particles with single-particle analysis and molecular dynamic simulations by Blanchette, Craig D., Law, Richard, Benner, W. Henry, Pesavento, Joseph B., Cappuccio, Jenny A., Walsworth, Vicki, Kuhn, Edward A., Corzett, Michele, Chromy, Brett A., Segelke, Brent W., Coleman, Matthew A., Bench, Graham, Hoeprich, Paul D., Sulchek, Todd A.

“…Self-assembly of purified apolipoproteins and phospholipids results in the formation of nanometer-sized lipoprotein complexes, referred to as nanolipoprotein…”
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Electrosynthesis of Ammonia Using Porous Bimetallic Pd–Ag Nanocatalysts in Liquid- and Gas-Phase Systems by Nazemi, Mohammadreza, Ou, Pengfei, Alabbady, Abdulaziz, Soule, Luke, Liu, Alan, Song, Jun, Sulchek, Todd A, Liu, Meilin, El-Sayed, Mostafa A

“…Cost-effective production of ammonia via electrochemical nitrogen reduction reaction (NRR) hinges on N2 electrolysis at high current densities with suitable…”
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Tuning Antibody Presentation to Enhance T‑Cell Activation for Downstream Cytotoxicity by Campbell, Elizabeth A, Ramirez, Katily, Holegadde, Meghana, Yeshlur, Nayana, Khaja, Akram, Sulchek, Todd A

“…Cytotoxic effector cells are an integral component of the immune response against pathogens and diseases such as cancer and thus of great interest to…”
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Enhanced stochastic fluctuations to measure steep adhesive energy landscapes by Haider, Ahmad, Potter, Daniel, Sulchek, Todd A.

“…Free-energy landscapes govern the behavior of all interactions in the presence of thermal fluctuations in the fields of physical chemistry, materials sciences,…”
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Reconstructing Multiwell Potentials with Steep Gradients Using Stochastically Excited Spring Probes by Haider, Ahmad, Potter, Daniel, Sulchek, Todd A

“…Measurements of free energy landscapes are critical for understanding the basis of many physical, chemical, and biological interactions. Statistical mechanics…”
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CGMP Compliant Microfluidic Transfection of Induced Pluripotent Stem Cells for CRISPR-Mediated Genome Editing by Bohrer, Laura R, Stone, Nicholas E, Wright, Allison T, Han, Sewoon, Sicher, Ian, Sulchek, Todd A, Mullins, Robert F, Tucker, Budd A

“…Abstract Inherited retinal degeneration is a term used to describe heritable disorders that result from the death of light sensing photoreceptor cells…”
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Cell-free expression for nanolipoprotein particles: building a high-throughput membrane protein solubility platform by Cappuccio, Jenny A, Hinz, Angela K, Kuhn, Edward A, Fletcher, Julia E, Arroyo, Erin S, Henderson, Paul T, Blanchette, Craig D, Walsworth, Vickie L, Corzett, Michele H, Law, Richard J, Pesavento, Joseph B, Segelke, Brent W, Sulchek, Todd A, Chromy, Brett A, Katzen, Federico, Peterson, Todd, Bench, Graham, Kudlicki, Wieslaw, Hoeprich, Jr, Paul D, Coleman, Matthew A

“…Membrane-associated proteins and protein complexes account for approximately a third or more of the proteins in the cell (1, 2). These complexes mediate…”
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Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics by Ni, Fang, Yu, Wen-Mei, Wang, Xinyi, Fay, Meredith E., Young, Katherine M., Qiu, Yongzhi, Lam, Wilbur A., Sulchek, Todd A., Cheng, Tao, Scadden, David T., Qu, Cheng-Kui

“…Hematopoietic stem cell (HSC) quiescence is a tightly regulated process crucial for hematopoietic regeneration, which requires a healthy and supportive…”
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