Search Results - "Sulaimon Akanmu, Alani"

Effect of nevirapine, efavirenz and lopinavir/ritonavir on the therapeutic concentration and toxicity of lumefantrine in people living with HIV at Lagos University Teaching Hospital, Nigeria by Usman, Sikiru Olatunji, Oreagba, Ibrahim Adekunle, Akinyede, Akinwumi Akinyinka, Agbaje, Esther Oluwatoyin, Akinleye, Moshood Olusola, Onwujuobi, Adaobi Goodness, Ken-Owotor, Chioma, Adeuja, Olatunbosun, Ogunfowokan, Tosin, Kogbe, Segun, Owolabi, Emmanuel Tope, Adeniji, Hannah, Busari, Abdul Wasiu, Hassan, Olayinka Olayiwola, Abideen, Ganiu, Akanmu, Alani Sulaimon

“…Patients living with HIV in malarial endemic regions may experience clinically significant drug interaction between antiretroviral and antimalarial drugs…”
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Adolescents and Young Adults Knowledge, Adherence and Experiences While on Antiretroviral Therapy in a Tertiary Hospital in Lagos, Nigeria: A Mixed-Method Study by Aderemi-Williams, Roseline Iberi, Razaq, Ayomikun Rofiat, Abah, Isaac Okoh, Opanuga, Olabisi Oluranti, Akanmu, Alani Sulaimon

“…In Nigeria, there is a paucity of data on knowledge and experiences of adolescents and young adults (AYAs) with HIV and ART, as well as their challenges…”
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Prevalence of HIV related oral lesions in people living with HIV and on combined antiretroviral therapy: a Nigerian experience by Mary, Eweka Olutola, Abiola, Ogbenna Ann, Titilola, Gbajabiamila, Mojirayo, Ogundana Oladunni, Sulaimon, Akanmu Alani

“…oral lesions comprise significant clinical features of HIV infection and are often indicators of immune suppression. However, the advent of antiretroviral…”
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High acceptability and viral suppression rate for first-Line patients on a dolutegravir-based regimen: An early adopter study in Nigeria by Abudiore, Opeyemi, Amamilo, Ikechukwu, Campbell, Jennifer, Eigege, Williams, Harwell, Joseph, Conroy, James, Jiboye, Justus, Lufadeju, Folu, Amole, Carolyn, Wiwa, Owens, Anweh, Damien, Agbaji, Oche Ochai, Akanmu, Alani Sulaimon

“…Nigeria adopted dolutegravir (DTG) as part of first line (1L) antiretroviral therapy (ART) in 2017. However, there is limited documented experience using DTG…”
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Accumulation of HIV-1 drug resistance after continued virological failure on first-line ART in adults and children in sub-Saharan Africa by Boender, T Sonia, Kityo, Cissy M, Boerma, Ragna S, Hamers, Raph L, Ondoa, Pascale, Wellington, Maureen, Siwale, Margaret, Nankya, Immaculate, Kaudha, Elizabeth, Akanmu, Alani Sulaimon, Botes, Mariette E, Steegen, Kim, Calis, Job C J, Rinke de Wit, Tobias F, Sigaloff, Kim C E

“…Limited availability of viral load (VL) monitoring in HIV treatment programmes in sub-Saharan Africa can delay switching to second-line ART, leading to the…”
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Evaluation of the effects of atazanavir-ritonavir on the pharmacokinetics of lumefantrine in patients living with HIV in Lagos University Teaching Hospital, South-Western Nigeria by Usman, Sikiru Olatunji, Oreagba, Ibrahim Adekunle, Kadri, Michael Rotimi, Adewumi, Ololade Oluwatosin, Akinyede, Akinwumi, Agbaje, Esther Oluwatoyin, Abideen, Ganiyu, Busari, AbdulWasiu Adeniyi, Hassan, Olayinka Olaiwola, Akinleye, Moshood Olusola, Akanmu, Alani Sulaimon

“…Purpose Atazanavir-ritonavir (ATVr)-based antiretroviral therapy and artemether-lumefantrine (AL) are commonly used drugs for the treatment of human immune…”
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The impact of HIV-1 subtypes on virologic and immunologic treatment outcomes at the Lagos University Teaching Hospital: A longitudinal evaluation by Ogbenna, Ann Abiola, Meloni, Seema, Inzaule, Seth, Hamers, Raph L, Sigaloff, Kim, Osibogun, Akin, Adeyemo, Titilope Adenike, Okonkwo, Prosper, Samuels, Jay Osi, Kanki, Phyllis J, Rinke de Wit, Tobias F, Akanmu, Alani Sulaimon

“…HIV is a highly diverse virus with significant genetic variability which may confer biologic differences that could impact on treatment outcomes. We studied…”
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Achieving a robust mentoring and research capacity program in a LMIC - the BRAINS faculty development model by Ogunsola, Folasade Tolulope, Sekoni, Adekemi, Akanmu, Alani Sulaimon, Adeyemo, Wasiu Lanre, Osuntoki, Akinniyi, Manga-Atangana, Bibiane, Afolabi, Bosede Bukola, Okubadejo, Njideka Ulunma, Emmanuel, Madonna, Caleb-Adepoju, Sikeade Olawumi, Folarin, Olalekan, Okonkwo, Prosper, Murphy, Robert L, Kanki, Phyllis

“…A research and training program (RTP) was carried out to build the capacity of faculty and improve the culture of research in the College of Medicine,…”
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Elevated homocysteine and crises state in patients with sickle cell anemia: A comparative study by Orolu, Adebukola, Adeyemo, Titilope, Akanmu, Alani

“…Background: High plasma concentration of homocysteine (Hcy) is a well-established risk factor for several disorders, including cardiovascular disease, stroke,…”
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Use of exchange blood transfusion in the management of severe COVID-19 infection in pregnancy: experience from Lagos, Nigeria by Bukola Afolabi, Bosede, Chigozie Makwe, Christian, Sharafadeen Okunade, Kehinde, Nurudeen Akanmu, Olanrewaju, Ephraim Akase, Iorhen, Otokiti, Oluwakemi, Bolarinwa, Abiola, Ezenwankwo, Francis, Olalekan Oyeleke, Gabriel, Nkolika Ezenwa, Beatrice, Martins-Akinlose, Oluwaseun, Ogundare, Titus, Iloka, Augustine, Sulaimon Akanmu, Alani

“…Coronavirus disease 2019 (COVID-19) presents with symptoms that may be mild or severe. The individual with the severe form of thedisease usually presents with…”
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Previous antiretroviral drug use compromises standard first-line HIV therapy and is mediated through drug-resistance by Inzaule, Seth C., Kityo, Cissy M., Siwale, Margaret, Akanmu, Alani Sulaimon, Wellington, Maureen, de Jager, Marleen, Ive, Prudence, Mandaliya, Kishor, Stevens, Wendy, Boender, T. Sonia, Ondoa, Pascale, Sigaloff, Kim C. E., Naniche, Denise, Rinke de Wit, Tobias F., Hamers, Raph L.

“…In ART programs in sub-Saharan Africa, a growing proportion of HIV-infected persons initiating first-line antiretroviral therapy (ART) have a history of prior…”
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Evaluation of cardiotoxicity and other adverse effects associated with concomitant administration of artemether/lumefantrine and atazanavir/ritonavir-based antiretroviral regimen in patients living with HIV by Usman, Sikiru Olatunji, Oreagba, Ibrahim Adekunle, Busari, AbdulWasiu, Akinyede, Akinwumi, Adewumi, Ololade, Kadri, Michael Rotimi, Hassan, Olayinka, Fashina, Yinka Adeyemi, Agbaje, Esther Oluwatoyin, Akanmu, Sulaimon Alani

“…The interplay of artemether-lumefantrine (AL) and atazanavir-ritonavir (ATVr) with Cytochrome P (CYP) 3A4 isoenzyme and QTc-interval may spawn clinically…”
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Correction to: Population data of 21 autosomal STR loci in the Hausa, Igbo and Yoruba people of Nigeria by Okolie, Victoria O., Cisana, Selena, Schanfield, Moses S., Akanmu, Alani Sulaimon, Adekoya, Khalid O., Oyedeji, Olufemi A., Podini, Daniele

“…In the original paper author Alani Sulaimon Akanmu was erroneously omitted from the author list. Prof. Akanmu has now been added as 4 th author. Prof. Akanmu…”
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High levels of pre‐treatment HIV drug resistance and treatment failure in Nigerian children by Boerma, Ragna S, Boender, T Sonia, Sigaloff, Kim C.E., Rinke de Wit, Tobias F, Hensbroek, Michael Boele, Ndembi, Nicaise, Adeyemo, Titilope, Temiye, Edamisan O, Osibogun, Akin, Ondoa, Pascale, Calis, Job C, Akanmu, Alani Sulaimon

“…Introduction Pre‐treatment HIV drug resistance (PDR) is an increasing problem in sub‐Saharan Africa. Children are an especially vulnerable population to…”
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Impact of the COVID-19 pandemic on global health research training and education by Hou, Lifang, Mehta, Supriya D, Christian, Elizabeth, Joyce, Brian, Lesi, Olufunmilayo, Anorlu, Rose, Akanmu, Alani Sulaimon, Imade, Godwin, Okeke, Edith, Musah, Jonah, Wehbe, Firas, Wei, Jian-Jun, Gursel, Demirkan, Klein, Kate, Achenbach, Chad J, Doobay-Persaud, Ashti, Holl, Jane, Maiga, Mamoudou, Traore, Cheick, Sagay, Atiene, Ogunsola, Folasade, Murphy, Robert

“…Since January 2020 billions of people across the world have been “locked down” and hundreds of thousands have died because of the COVID-19 global pandemic. The…”
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Modeling cerebellar limb dysmetria and impaired spatial memory in rats using lamivudine: A preliminary study by Akang, Edidiong, Dosumu, Olufunke, Afolayan, Samuel, Agumah, Rhoda, Akanmu, Alani Sulaimon

“…•Lamivudine increases neuroinflammatory response of CD68 in cerebellum.•Lamivudine causes marked reactive astrocytosis.•Purkinje and pyramidal neurons are…”
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Pretreatment HIV Drug Resistance Increases Regimen Switches in Sub-Saharan Africa by Boender, T. Sonia, Hoenderboom, Bernice M., Sigaloff, Kim C. E., Hamers, Raph L., Wellington, Maureen, Shamu, Tinei, Siwale, Margaret, Maksimos, Eman E. F. Labib, Nankya, Immaculate, Kityo, Cissy M., Adeyemo, Titilope A., Akanmu, Alani Sulaimon, Mandaliya, Kishor, Botes, Mariette E., Ondoa, Pascale, de Wit, Tobias F. Rinke

“…Background. After the scale-up of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection in Africa, increasing numbers of patients have…”
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Protease Inhibitor Resistance in the First 3 Years of Second-Line Antiretroviral Therapy for HIV-1 in Sub-Saharan Africa by Boender, T. Sonia, Hamers, Raph L., Ondoa, Pascale, Wellington, Maureen, Chimbetete, Cleophas, Siwale, Margaret, Maksimos, Eman E. F. Labib, Belinda, Sheila N., Kityo, Cissy M., Adeyemo, Titilope A., Akanmu, Alani Sulaimon, Mandaliya, Kishor, Botes, Mariette E., Stevens, Wendy, de Wit, Tobias F. Rinke, Sigaloff, Kim E.

“…Background. As antiretroviral therapy (ART) programs in sub-Saharan Africa mature, increasing numbers of persons with human immunodeficiency virus (HIV)…”
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Association between HIV-1 subtype and drug resistance in Nigerian infants by Chaplin, Beth, Akanmu, Alani Sulaimon, Inzaule, Seth C, Samuels, Jay Osi, Okonkwo, Prosper, Ilesanmi, Oluwafunke, Adewole, Isaac F A, Asadu, Chukwuemeka, Khamofu, Hadiza, Mpazanje, Rex, Ndembi, Nicaise, Odafe, Solomon, Sigaloff, Kim C E, Ngige, Evelyn Nkadi, Abatta, Emmanuel Okechukwu, Akinbiyi, Gbenga, Dakum, Patrick, Rinke de Wit, Tobias F, Kanki, Phyllis

“…Abstract Background Many lines of evidence point to HIV-1 subtype-specific differences in the development of drug resistance mutations. While variation between…”
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Microscopic and biochemical changes on liver and kidney of Wistar rats on combination antiretroviral therapy: the impact of naringenin and quercetin by Akang, Edidiong Nnamso, Dosumu, Olufunke O, Okoko, Ini-ibehe Essien, Faniyan, Oluwatomisin, Oremosu, Ademola A, Akanmu, Alani Sulaimon

“…Abstract Combination antiretroviral therapy (cART), which is a lifelong therapy for people living with human immunodeficiency virus, has been associated with…”
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