Search Results - "Sulaiman, K."

mTOR: Its Critical Role in Metabolic Diseases, Cancer, and the Aging Process by Marafie, Sulaiman K, Al-Mulla, Fahd, Abubaker, Jehad

“…The mammalian target of rapamycin (mTOR) is a pivotal regulator, integrating diverse environmental signals to control fundamental cellular functions, such as…”
Get full text

Contributions of energy pathways to ATP production and pH variations in postmortem muscles by Wang, Chengcheng, Matarneh, Sulaiman K., Gerrard, David, Tan, Jinglu

“…The roles of energy pathways in postmortem muscles are still debated. In this study, the contributions of different pathways to ATP production and pH…”
Get full text

Modelling of energy metabolism and analysis of pH variations in postmortem muscle by Wang, Chengcheng, Matarneh, Sulaiman K., Gerrard, David, Tan, Jinglu

“…A kinetic model structure was developed to describe the major variations in energy metabolism and to gain further understanding of pH changes in postmortem…”
Get full text

Higher binding affinity of furin for SARS-CoV-2 spike (S) protein D614G mutant could be associated with higher SARS-CoV-2 infectivity by Mohammad, Anwar, Alshawaf, Eman, Marafie, Sulaiman K., Abu-Farha, Mohamed, Abubaker, Jehad, Al-Mulla, Fahd

“…•The G clade 23403A>G mutation on the spike glycoprotein (S protein) encodes a virulent strain of SARS-CoV-2.•The D614G substitution causes the loss of a…”
Get full text

Factors associated with psychiatric disorders and treatment seeking behaviour among older adults in India by Srivastava, Shobhit, Sulaiman, KM, Drishti, Drishti, Muhammad, T.

“…Since untreated or undertreated late-life mental disorders is associated with grave consequences including poor quality of life and increased mortality rates,…”
Get full text

New Insights in Muscle Biology that Alter Meat Quality by Matarneh, Sulaiman K, Silva, Saulo L, Gerrard, David E

“…Fresh meat quality is greatly determined through biochemical changes occurring in the muscle during its conversion to meat. These changes are key to imparting…”
Get full text

Types of household headship and associated life satisfaction among older adults in India: findings from LASI survey, 2017-18 by Srivastava, Shobhit, Muhammad, T, Sulaiman, K M, Kumar, Manish, Singh, S K

“…Household headship with decision-making power may have a positive influence on life satisfaction in older adults. This study examines the associations of…”
Get full text

Notoginsenoside R1, a metabolite from Panax notoginseng (Burkill) F.H.Chen, stimulates insulin secretion through activation of phosphatidylinositol 3-kinase (PI3K)/Akt pathway by Al-Romaiyan, Altaf, Barakat, Ahmad, Marafie, Sulaiman K, Masocha, Willias

“…For ages, botanical medicine has been used in the treatment of diabetes mellitus (DM). Notoginsenoside R1 (NGR1), a Panax notoginseng (Burkill) F.H.Chen…”
Get full text

Structural analysis of ACE2 variant N720D demonstrates a higher binding affinity to TMPRSS2 by Mohammad, Anwar, Marafie, Sulaiman K., Alshawaf, Eman, Abu-Farha, Mohamed, Abubaker, Jehad, Al-Mulla, Fahd

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel member of the betacoronaviruses family affecting the lower respiratory tract mainly…”
Get full text

An Overview of the Role of Furin in Type 2 Diabetes by Marafie, Sulaiman K., Al-Mulla, Fahd

“…Post-translational modifications (PTMs) play important roles in regulating several human diseases, like cancer, neurodegenerative disorders, and metabolic…”
Get full text

Mitochondria influence glycolytic and tricarboxylic acid cycle metabolism under postmortem simulating conditions by Matarneh, Sulaiman K., Yen, Con-Ning, Bodmer, Jocelyn, El-Kadi, Samer W., Gerrard, David E.

“…The purpose of this study was to test mitochondrial functionality under conditions simulating postmortem metabolism. Isolated mitochondria from porcine…”
Get full text

Inhibition of mitochondrial calcium uniporter enhances postmortem proteolysis and tenderness in beef cattle by Dang, David S., Buhler, Jared F., Davis, Haden T., Thornton, Kara J., Scheffler, Tracy L., Matarneh, Sulaiman K.

“…The purpose of this study was to examine the role of mitochondria in postmortem calcium homeostasis and its effect on proteolysis and tenderness. We…”
Get full text

Analysis of phosphofructokinase-1 activity as affected by pH and ATP concentration by Wang, Chengcheng, Taylor, Mackenzie J., Stafford, Chandler D., Dang, David S., Matarneh, Sulaiman K., Gerrard, David E., Tan, Jinglu

“…A key player in energy metabolism is phosphofructokinase-1 (PFK1) whose activity and behavior strongly influence glycolysis and thus have implications in many…”
Get full text

Food insecurity and associated depression among older adults in India: evidence from a population-based study by T, Muhammad, Sulaiman, KM, Drishti, Drishti, Srivastava, Shobhit

“…ObjectiveThe present study aimed to examine the associations of several indicators of food insecurity with depression among older adults in India.DesignA…”
Get full text

Presence of oxygen and mitochondria in skeletal muscle early postmortem by England, Eric M., Matarneh, Sulaiman K., Mitacek, Rachel M., Abraham, Anupam, Ramanathan, Ranjith, Wicks, Jordan C., Shi, Hao, Scheffler, Tracy L., Oliver, Emily M., Helm, Emma T., Gerrard, David E.

“…Anaerobic glycolysis dominates energy metabolism postmortem. Even so, however, recent studies suggest mitochondria can modify postmortem energy metabolism and…”
Get full text

Mitochondria influence postmortem metabolism and pH in an in vitro model by Scheffler, Tracy L., Matarneh, Sulaiman K., England, Eric M., Gerrard, David E.

“…Our objective was to determine the influence of mitochondria on metabolites and pH decline using an in vitro model of postmortem muscle metabolism…”
Get full text

Excess glycogen does not resolve high ultimate pH of oxidative muscle by England, Eric M., Matarneh, Sulaiman K., Oliver, Emily M., Apaoblaza, Ariel, Scheffler, Tracy L., Shi, Hao, Gerrard, David E.

“…Skeletal muscle glycogen content can impact the extent of postmortem pH decline. Compared to glycolytic muscles, oxidative muscles contain lower glycogen…”
Get full text

Ultrasonication of beef improves calpain-1 autolysis and caspase-3 activity by elevating cytosolic calcium and inducing mitochondrial dysfunction by Dang, David S., Stafford, Chandler D., Taylor, Mackenzie J., Buhler, Jared F., Thornton, Kara J., Matarneh, Sulaiman K.

“…The objective of this study was to investigate if ultrasonication of bovine longissimus thoracis et lumborum (LTL) steaks increases calpain-1 and caspase-3…”
Get full text

Mitochondrial F1-ATPase extends glycolysis and pH decline in an in vitro model by Matarneh, Sulaiman K., Beline, Mariane, de Luz e Silva, Saulo, Shi, Hao, Gerrard, David E.

“…The experiment was conducted to identify the mitochondrial protein responsible for enhancing glycolytic flux. We hypothesized that mitochondrial F1-ATPase…”
Get full text

Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells by Marafie, Sulaiman K, Al-Shawaf, Eman M, Abubaker, Jehad, Arefanian, Hossein

“…Free fatty acid receptor 1 (FFAR1) is G-protein coupled receptor predominantly expressed in pancreatic β-cells that is activated by a variety of free fatty…”
Get full text