Search Results - "Sulaiman, Abdallah Alhaj"
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Can Cisplatin Therapy Be Improved? Pathways That Can Be Targeted
Published in International journal of molecular sciences (01-07-2022)“…Cisplatin (cis-diamminedichloroplatinum (II)) is the oldest known chemotherapeutic agent. Since the identification of its anti-tumour activity, it earned a…”
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The histone H2B Arg95 residue links the pheromone response pathway to rapamycin-induced G1 arrest in yeast
Published in Scientific reports (15-06-2022)“…Rapamycin is an immunosuppressant used for treating many types of diseases such as kidney carcinomas. In yeast, rapamycin inhibits the TORC1 kinase signaling…”
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Journal Article -
3
The Yeast Permease Agp2 Senses Cycloheximide and Undergoes Degradation That Requires the Small Protein Brp1-Cellular Fate of Agp2 in Response to Cycloheximide
Published in International journal of molecular sciences (01-04-2023)“…The Agp2 is a plasma membrane protein initially reported to be an uptake transporter for L-carnitine. Agp2 was later rediscovered, together with three…”
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Altered Regulation of the Glucose Transporter GLUT3 in PRDX1 Null Cells Caused Hypersensitivity to Arsenite
Published in Cells (Basel, Switzerland) (22-11-2023)“…Targeting tumour metabolism through glucose transporters is an attractive approach. However, the role these transporters play through interaction with other…”
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The histone H2B Arg95 residue efficiently recruits the transcription factor Spt16 to mediate Ste5 expression of the pheromone response pathway
Published in Scientific reports (22-06-2023)“…In yeast Saccharomyces cerevisiae , the immunosuppressant rapamycin inhibits the TORC1 kinase causing rapid alteration in gene expression and leading to G 1…”
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Loss of the yeast transporter Agp2 upregulates the pleiotropic drug-resistant pump Pdr5 and confers resistance to the protein synthesis inhibitor cycloheximide
Published in PloS one (22-05-2024)“…The transmembrane protein Agp2, initially shown as a transporter of L-carnitine, mediates the high-affinity transport of polyamines and the anticancer drug…”
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A Systematic Review and Comprehensive Analysis of mcr Gene Prevalence in Bacterial Isolates in Arab Countries
Published in Antibiotics (Basel) (11-10-2024)“…The resurgence of colistin has become critical in combating multidrug-resistant Gram-negative bacteria. However, the emergence of mobilized colistin resistance…”
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Mft1, identified from a genome-wide screen of the yeast haploid mutants, mediates cell cycle arrest to counteract quinoxaline-induced toxicity
Published in Frontiers in genetics (2023)“…Quinoxaline is a heterocyclic compound with a two-membered ring structure that undergoes redox cycling to produce toxic free radicals. It has antiviral,…”
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9
First Nation-Wide Analysis of Food Safety and Acceptability Data in Lebanon
Published in Foods (01-11-2020)“…The challenges to food safety in Lebanon are numerous and have coalesced to pose a serious public health concern. This is evident in well-documented food…”
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Journal Article -
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First report of the mobile colistin resistance gene, mcr-1.26, in multidrug-resistant Escherichia coli isolated from retail chicken meat
Published in Journal of global antimicrobial resistance. (01-09-2023)“…We isolated a highly colistin-resistant Escherichia coli, strain 58, from fresh chicken wings in Lebanon. Here, we performed in-depth phenotypic and genomic…”
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Draft Genome Sequences of Multidrug-Resistant and mcr-1.1 -Harboring Escherichia coli Isolated from Drinking and Well Waters Used in Syrian Refugee Camps
Published in Microbiology resource announcements (14-01-2021)“…Resistance to colistin, a last-resort antibiotic, threatens the treatment of complicated infections, especially in susceptible populations such as Syrian…”
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The Histone H2B Arg95 Residue Recruits Spt16 to Maintain a Proper Expression of STE5 Required for Transmitting Rapamycin-Induced G1 Arrest in Saccharomyces cerevisiae
Published 01-01-2024“…The immunosuppressant rapamycin inhibits the TORC1 kinase pathway in yeast, leading to cell cycle arrest through a mechanism that is not fully understood. To…”
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Dissertation -
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The histone H2B Arg95 residue links the pheromone response pathway to rapamycin-induced G 1 arrest in yeast
Published in Scientific reports (15-06-2022)“…Rapamycin is an immunosuppressant used for treating many types of diseases such as kidney carcinomas. In yeast, rapamycin inhibits the TORC1 kinase signaling…”
Get full text
Journal Article