Search Results - "Sukuroglu, Murat"

In vivo and in vitro antidiabetic effect of Cistus laurifolius L. and detection of major phenolic compounds by UPLC–TOF-MS analysis by Orhan, Nilüfer, Aslan, Mustafa, Şüküroğlu, Murat, Deliorman Orhan, Didem

“…In Turkish folk medicine, various parts of Cistus laurifolius L. are used to treat gastric ulcer and various types of pains. Additionally the tea prepared from…”
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Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors by Hawash, Mohammed, Jaradat, Nidal, Abualhasan, Murad, Şüküroğlu, Murat Kadır, Qaoud, Mohammed T., Kahraman, Deniz Cansen, Daraghmeh, Heba, Maslamani, Leen, Sawafta, Mais, Ratrout, Ala, Issa, Linda

“…Background Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the most commonly used class of medications worldwide for the last three decades. Objectives…”
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The potential of 4-aryl-6-morpholino-3(2H)-pyridazinone-2-arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by pharmacophore mapping and molecular docking by Sukuroglu, Murat Kadir, Gozelle, Mahmut, Ozkan, Yesim, Eren, Gokcen

“…Numerous studies have demonstrated that the aberrant enzymatic activity of SIRTs has been linked to various diseases like diabetes, cancer, inflammation,…”
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UPLC–TOF-MS analysis of Galium spurium towards its neuroprotective and anticonvulsant activities by Orhan, Nilüfer, Deliorman Orhan, Didem, Aslan, Mustafa, Şüküroğlu, Murat, Orhan, Ilkay Erdogan

“…Galium species have been reported to be used against epilepsy in traditional Turkish folk medicine. The present work was undertaken to evaluate the in vivo…”
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Crystal Structure and Vibrational Spectra of 3-Chloro-4-Phenyl-6-(Morpholine-4-yl)-Pyridazine by Hartree-Fock and Density Functional Methods by Aydin, Abdullah, Arslan, Hakan, Şüküroğlu, Murat, Akkurt, Mehmet, Büyükgüngör, Orhan

“…The title compound, 3-chloro-4-phenyl-6-(morpholine-4-yl)-pyridazine (I), was prepared and characterized using elemental analysis and FT-IR and 1 H NMR…”
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The Release Pattern of Liposomal Bupivacaine in the Artificial Cerebrospinal Fluid by Ayşe Ünal Düzlü, Günaydın, Berrin, Murat Kadir Şüküroğlu, İsmail Tuncer Değim

“…INTRODUCTION: We aimed to compare the possible controlled release profile of multilamellar liposomal bupivacaine formulations with non-liposomal forms in…”
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Relation of kynurenine/tryptophan with immune and inflammatory markers in coronary artery disease by Ozkan, Yesim, Sukuroglu, Murat Kadir, Tulmac, Murat, Kisa, Ucler, Simsek, Bolkan

“…Inflammation and immune activation have a crucial role in the pathogenesis of cardiovascular diseases. Indolamine 2,3-dioxygenase, a tryptophan catabolising…”
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Evaluation of Tryptophan/Kynurenine Pathway Relevance With Immune System Biomarkers of Low Energy Trauma Hip Fractures in Osteoporotic Patients by Ozkan, Yesim, Dincel, Aylin Sepici, Dincel, Ercan, Ozsoy, Hakan, Sukuroglu, Murat

“…This study aims to evaluate tryptophan degradation and clarify whether altered levels of kynurenine and tryptophan (Kyn/Trp) ratio could be correlated to…”
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Simultaneous Determination of Paracetamol, Phenylephrine Hydrochloride, Oxolamine Citrate and Chlorpheniramine Maleate by HPLC in Pharmaceutical Dosage Forms by Ozan Pirol, Murat Sukuroglu, Tuncel Ozden

“…A new high performance liquid chromatographic (HPLC) method was developed for the determination of paracetamol, phenylephrine hydrochloride, oxolamine citrate…”
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2-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl}-6-(morpholin-4-yl)-4-phenylpyridazin-3(2 H )-one by Aydın, Abdullah, Şüküroğlu, Murat, Akkurt, Mehmet, Büyükgüngör, Orhan

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Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity by Ozmen Ozgun, Dilan, Gul, Halise Inci, Yamali, Cem, Sakagami, Hiroshi, Gulcin, Ilhami, Sukuroglu, Murat, Supuran, Claudiu T.

“…[Display omitted] •Sulfonamide derivatives bearing pyrazoline ring can be considered as CAs and AChE inhibitors.•Ki values were in the range of 27.9–74.3 nM…”
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Crystal structure of 4-(4-chloro-phen-yl)-6-(morpholin-4-yl)pyridazin-3(2H)-one by Aydın, Abdullah, Akkurt, Mehmet, Şüküroğlu, Murat, Büyükgüngör, Orhan

“…In the title compound, C14H14ClN3O2, the morpholine ring adopts a chair conformation, with the exocyclic N-C bond in an equatorial orientation. The…”
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Screening and evaluation of antioxidant activity of some pyridazine derivatives by Caliskan-Ergün, Burcu, Süküroğlu, Murat, Coban, Tulay, Banoğlu, Erden, Suzen, Sibel

“…Antioxidants are compounds that can delay, inhibit, or prevent the oxidation of materials that can be oxidized by scavenging free radicals and help in…”
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Synthesis of some new 2,6-disubstituted-3(2H)-pyridazinone derivatives and investigation of their analgesic, anti-inflammatory and antimicrobial activities by Tiryaki, Didem, Sukuroglu, Murat, Dogruer, Deniz S., Akkol, Esra, Ozgen, Selda, Sahin, M. Fethi

“…In this study, 12 new 3(2 H )-pyridazinone derivatives carrying 4-substituted phenylpiperazinylethyl moiety on lactam nitrogen were synthesized and their…”
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Synthesis, Analgesic, and Anti-Inflammatory Activities of [6-(3,5-Dimethyl-4-Chloropyrazole-1-yl)-3(2H)-Pyridazinon-2-yl]Acetamides by Sukuroglu, Murat, Caliskanergun, Burcu, Unlu, Serdar, Sahin, M.Fethi, Kupeli, Esra, Yesilada, Erdem, Banoglu, Erden

“…A series of structurally diverse amide derivatives of [6-(3,5-dimethyl-4- chloro-pyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic acid were prepared and tested…”
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Synthesis of new N,N'-bis[1-aryl-3-(piperidine-1-yl)propylidene]hydrazine dihydrochlorides and evaluation of their cytotoxicity against human hepatoma and breast cancer cells by Kucukoglu, Kaan, Gul, H Inci, Cetin-Atalay, Rengul, Baratli, Yosra, Charles, Anne-Laure, Sukuroglu, Murat, Gul, Mustafa, Geny, Bernard

“…N,N'-Bis[1-aryl-3-(piperidine-1-yl)propylidene]hydrazine dihydrochlorides were synthesized by the reaction of 2 mols of 1-aryl-3-(piperidine-1-yl)-1-propanone…”
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Synthesis and in vitro Biological Activity of New 4,6-Disubstituted 3(2H)-Pyridazinone-acetohydrazide Derivatives by Sukuroglu, Murat, Onkol, Tijen, Onurdag, Fatma Kaynak, Akalin, Gulsen, Sahin, M. Fethi

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Screening and evaluation of rat kidney aldose reductase inhibitory activity of some pyridazine derivatives by Şüküroğlu, Murat, Çalişkan-Ergün, Burcu, Das-Evcimen, Net, Sarikaya, Mutlu, Banoğlu, Erden, Suzen, Sibel

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Synthesis and in vitro Biological Activity of New 4,6-Disubstituted 3(2H)-Pyridazinone-acetohydrazide Derivatives by Sukuroglu, Murat, Onkol, Tijen, Onurdağ, Fatma Kaynak, Akalın, Gulsen, Şahin, M. Fethi

“…New 3(2H)-pyridazinone derivatives containing a N’-benzyliden-acetohydrazide moiety at position 2 were synthesized. The structures of these newly synthesized…”
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2-{2-[4-(4-Fluoro-phen-yl)piperazin-1-yl]-2-oxoeth-yl}-6-(morpholin-4-yl)-4-phenyl-pyridazin-3(2H)-one by Aydın, Abdullah, Süküroğlu, Murat, Akkurt, Mehmet, Büyükgüngör, Orhan

“…In the title compound, C(26)H(28)FN(5)O(3), the morpholine ring adopts a chair conformation. The piperazine ring is puckered [Q(T) = 0.5437 (15) Å, θ = 8.89…”
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