Search Results - "Sukkurwala, Abdul Qader"

Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells by Ma, Yuting, Adjemian, Sandy, Mattarollo, Stephen R., Yamazaki, Takahiro, Aymeric, Laetitia, Yang, Heng, Portela Catani, João Paulo, Hannani, Dalil, Duret, Helene, Steegh, Kim, Martins, Isabelle, Schlemmer, Frederic, Michaud, Mickaël, Kepp, Oliver, Sukkurwala, Abdul Qader, Menger, Laurie, Vacchelli, Erika, Droin, Nathalie, Galluzzi, Lorenzo, Krzysiek, Roman, Gordon, Siamon, Taylor, Philip R., Van Endert, Peter, Solary, Eric, Smyth, Mark J., Zitvogel, Laurence, Kroemer, Guido

“…The therapeutic efficacy of anthracyclines relies on antitumor immune responses elicited by dying cancer cells. How chemotherapy-induced cell death leads to…”
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Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice by Michaud, Mickaël, Martins, Isabelle, Sukkurwala, Abdul Qader, Adjemian, Sandy, Ma, Yuting, Pellegatti, Patrizia, Shen, Shensi, Kepp, Oliver, Scoazec, Marie, Mignot, Grégoire, Rello-Varona, Santiago, Tailler, Maximilien, Menger, Laurie, Vacchelli, Erika, Galluzzi, Lorenzo, Ghiringhelli, François, di Virgilio, Francesco, Zitvogel, Laurence, Kroemer, Guido

“…Antineoplastic chemotherapies are particularly efficient when they elicit immunogenic cell death, thus provoking an anticancer immune response. Here we…”
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Molecular determinants of immunogenic cell death elicited by anticancer chemotherapy by Kepp, Oliver, Galluzzi, Lorenzo, Martins, Isabelle, Schlemmer, Frederic, Adjemian, Sandy, Michaud, Mickael, Sukkurwala, Abdul Qader, Menger, Laurie, Zitvogel, Laurence, Kroemer, Guido

“…The success of some chemo- and radiotherapeutic regimens relies on the induction of immunogenic tumor cell death and on the induction of an anticancer immune…”
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Cisplatin Resistance Associated with PARP Hyperactivation by MICHELS, Judith, VITALE, Ilio, TALBOT, Monique, ROBIN, Angélique, GIRARD, Philippe, OREAR, Cedric, LISSA, Delphine, ABDUL QADER SUKKURWALA, GARCIA, Pauline, BEHNAM-MOTLAGH, Parviz, KOHNO, Kimitoshi, GEN SHENG WU, GALLUZZI, Lorenzo, BRENNER, Catherine, DESSEN, Philippe, SAPARBAEV, Murat, SORIA, Jean-Charles, CASTEDO, Maria, KROEMER, Guido, ADAM, Julien, ANDRE OLAUSSEN, Ken, KEPP, Oliver, SENOVILLA, Laura, TALHAOUI, Ibtissam, GUEGAN, Justine, PIERRE ENOT, David

“…Non-small cell lung carcinoma patients are frequently treated with cisplatin (CDDP), most often yielding temporary clinical responses. Here, we show that PARP1…”
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Premortem autophagy determines the immunogenicity of chemotherapy-induced cancer cell death by Martins, Isabelle, Michaud, Mickaël, Sukkurwala, Abdul Qader, Adjemian, Sandy, Ma, Yuting, Shen, Shensi, Kepp, Oliver, Menger, Laurie, Vacchelli, Erika, Galluzzi, Lorenzo, Zitvogel, Laurence, Kroemer, Guido

“…One particular strategy to render anticancer therapies efficient consists of converting the patient's own tumor cells into therapeutic vaccines, via the…”
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Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens by Ladoire, Sylvain, Chaba, Kariman, Martins, Isabelle, Sukkurwala, Abdul Qader, Adjemian, Sandy, Michaud, Mickaël, Poirier-Colame, Vichnou, Andreiuolo, Felipe, Galluzzi, Lorenzo, White, Eileen, Rosenfeldt, Mathias, Ryan, Kevin M., Zitvogel, Laurence, Kroemer, Guido

“…Autophagy is an evolutionarily conserved catabolic process that involves the entrapment of cytoplasmic components within characteristic vesicles for their…”
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ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy by Ma, Yuting, Adjemian, Sandy, Yang, Heng, Catani, João Paulo Portela, Hannani, Dalil, Martins, Isabelle, Michaud, Mickaël, Kepp, Oliver, Sukkurwala, Abdul Qader, Vacchelli, Erika, Galluzzi, Lorenzo, Zitvogel, Laurence, Kroemer, Guido

“…Tumor cells succumb to chemotherapy while releasing ATP. We have found that extracellular ATP attracts dendritic cell (DC) precursors into the tumor bed,…”
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Subversion of the chemotherapy-induced anticancer immune response by the ecto-ATPase CD39 by Michaud, Mickaël, Sukkurwala, Abdul Qader, Martins, Isabelle, Shen, Shensi, Zitvogel, Laurence, Kroemer, Guido

“…The efficacy of antineoplastic chemotherapies with anthracyclines or oxaliplatin relies on the induction of immunogenic cell death, thus provoking an…”
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Loss-of-function alleles of P2RX7 and TLR4 fail to affect the response to chemotherapy in non-small cell lung cancer by Vacchelli, Erika, Galluzzi, Lorenzo, Rousseau, Vanessa, Rigoni, Alice, Tesniere, Antoine, Delahaye, Nicolas, Schlemmer, Fre´de´ric, Menger, Laurie, Sukkurwala, Abdul Qader, Adjemian, Sandy, Martins, Isabelle, Michaud, Mickaël, Dunant, Ariane, Kepp, Oliver, Brambilla, Elisabeth, Soria, Jean-Charles, Zitvogel, Laurence, Kroemer, Guido

“…The success of anticancer chemotherapy relies at least in part on the induction of an immune response against tumor cells. Thus, tumors growing on mice that…”
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Crosstalk between ER stress and immunogenic cell death by Kepp, Oliver, Menger, Laurie, Vacchelli, Erika, Locher, Clara, Adjemian, Sandy, Yamazaki, Takahiro, Martins, Isabelle, Sukkurwala, Abdul Qader, Michaud, Michael, Senovilla, Laura, Galluzzi, Lorenzo, Kroemer, Guido, Zitvogel, Laurence

“…Abstract Preclinical and clinical findings suggest that tumor-specific immune responses may be responsible – at least in part – for the clinical success of…”
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Cardiac glycosides exert anticancer effects by inducing immunogenic cell death by Menger, Laurie, Vacchelli, Erika, Adjemian, Sandy, Martins, Isabelle, Ma, Yuting, Shen, Shensi, Yamazaki, Takahiro, Sukkurwala, Abdul Qader, Michaud, Mickaël, Mignot, Grégoire, Schlemmer, Frederic, Sulpice, Eric, Locher, Clara, Gidrol, Xavier, Ghiringhelli, François, Modjtahedi, Nazanine, Galluzzi, Lorenzo, André, Fabrice, Zitvogel, Laurence, Kepp, Oliver, Kroemer, Guido

“…Some successful chemotherapeutics, notably anthracyclines and oxaliplatin, induce a type of cell stress and death that is immunogenic, hence converting the…”
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Screening of novel immunogenic cell death inducers within the NCI Mechanistic Diversity Set by Sukkurwala, Abdul Qader, Adjemian, Sandy, Senovilla, Laura, Michaud, Mickaël, Spaggiari, Sabrina, Vacchelli, Erika, Baracco, Elisa Elena, Galluzzi, Lorenzo, Zitvogel, Laurence, Kepp, Oliver, Kroemer, Guido

“…Immunogenic cell death (ICD) inducers can be defined as agents that exert cytotoxic effects while stimulating an immune response against dead cell-associated…”
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EGFR inhibitors exacerbate differentiation and cell cycle arrest induced by retinoic acid and vitamin D3 in acute myeloid leukemia cells by Lainey, Elodie, Wolfromm, Alice, Sukkurwala, Abdul Qader, Micol, Jean-Baptiste, Fenaux, Pierre, Galluzzi, Lorenzo, Kepp, Oliver, Kroemer, Guido

“…By means of an unbiased, automated fluorescence microscopy-based screen, we identified the epidermal growth factor receptor (EGFR) inhibitors erlotinib and…”
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Anticancer activity of cardiac glycosides: At the frontier between cell-autonomous and immunological effects by Kepp, Oliver, Menger, Laurie, Vacchelli, Erika, Adjemian, Sandy, Martins, Isabelle, Ma, Yuting, Sukkurwala, Abdul Qader, Michaud, Mickaël, Galluzzi, Lorenzo, Zitvogel, Laurence, Kroemer, Guido

“…Retrospective clinical data indicate that cardiac glycosides (CGs), notably digoxin, prolong the survival of carcinoma patients treated with conventional…”
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Synthetic induction of immunogenic cell death by genetic stimulation of endoplasmic reticulum stress by Michaud, Mickaël, Sukkurwala, Abdul Qader, Di Sano, Federica, Zitvogel, Laurence, Kepp, Oliver, Kroemer, Guido

“…Cis-diamminedichloridoplatinum(II) (CDDP), commonly referred to as cisplatin, is a chemotherapeutic drug used for the treatment of a wide range of solid…”
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Abstract 2262: Contribution of autophagy in anticancer immune response induced by chemotherapy by Sukkurwala, Abdul Qader, Michaud, Mickaël, Martins, Isabelle, Kroemer, Guido

“…Abstract Antineoplastic chemotherapies are particularly efficient when they elicit immunogenic cell death, thus provoking an anticancer immune response. We…”
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Consensus guidelines for the detection of immunogenic cell death by Kepp, Oliver, Senovilla, Laura, Vitale, Ilio, Vacchelli, Erika, Adjemian, Sandy, Agostinis, Patrizia, Apetoh, Lionel, Aranda, Fernando, Barnaba, Vincenzo, Bloy, Norma, Bracci, Laura, Breckpot, Karine, Brough, David, Buqué, Aitziber, Castro, Maria G., Cirone, Mara, Colombo, Maria I., Cremer, Isabelle, Demaria, Sandra, Dini, Luciana, Eliopoulos, Aristides G., Faggioni, Alberto, Formenti, Silvia C., Fučíková, Jitka, Gabriele, Lucia, Gaipl, Udo S., Galon, Jérôme, Garg, Abhishek, Ghiringhelli, François, Giese, Nathalia A., Guo, Zong Sheng, Hemminki, Akseli, Herrmann, Martin, Hodge, James W., Holdenrieder, Stefan, Honeychurch, Jamie, Hu, Hong-Min, Huang, Xing, Illidge, Tim M., Kono, Koji, Korbelik, Mladen, Krysko, Dmitri V., Loi, Sherene, Lowenstein, Pedro R., Lugli, Enrico, Ma, Yuting, Madeo, Frank, Manfredi, Angelo A., Martins, Isabelle, Mavilio, Domenico, Menger, Laurie, Merendino, Nicolò, Michaud, Michael, Mignot, Gregoire, Mossman, Karen L., Multhoff, Gabriele, Oehler, Rudolf, Palombo, Fabio, Panaretakis, Theocharis, Pol, Jonathan, Proietti, Enrico, Ricci, Jean-Ehrland, Riganti, Chiara, Rovere-Querini, Patrizia, Rubartelli, Anna, Sistigu, Antonella, Smyth, Mark J., Sonnemann, Juergen, Spisek, Radek, Stagg, John, Sukkurwala, Abdul Qader, Tartour, Eric, Thorburn, Andrew, Thorne, Stephen H., Vandenabeele, Peter, Velotti, Francesca, Workenhe, Samuel T., Yang, Haining, Zong, Wei-Xing, Zitvogel, Laurence, Kroemer, Guido, Galluzzi, Lorenzo

“…Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit immune responses specific for dead cell-associated antigens…”
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EGFR inhibitors exacerbate differentiation and cell cycle arrest induced by retinoic acid and vitamin D 3 in acute myeloid leukemia cells by Lainey, Elodie, Wolfromm, Alice, Sukkurwala, Abdul Qader, Micol, Jean-Baptiste, Fenaux, Pierre, Galluzzi, Lorenzo, Kepp, Oliver, Kroemer, Guido

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Molecular determinants of immunogenic cell death elicited by anticancer chemotherapy: Immunity and Tumor Growth and Metastasis by KEPP, Oliver, GALLUZZI, Lorenzo, MARTINS, Isabelle, SCHLEMMER, Frederic, ADJEMIAN, Sandy, MICHAUD, Mickael, QADER SUKKURWALA, Abdul, MENGER, Laurie, ZITVOGEL, Laurence, KROEMER, Guido

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Fluorescent biosensors for the detection of HMGB1 release by Martins, Isabelle, Kepp, Oliver, Menger, Laurie, Michaud, Mickäel, Adjemian, Sandy, Sukkurwala, Abdul Qader, Vacchelli, Erika, Galluzzi, Lorenzo, Kroemer, Guido

“…During necrosis and following some instances of apoptosis (in particular in the absence of a proficient phagocytic system), the nonhistone chromatin component…”
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