Search Results - "Sukhtankar, Devki D."

Physiological function of gastrin-releasing peptide and neuromedin B receptors in regulating itch scratching behavior in the spinal cord of mice by Sukhtankar, Devki D, Ko, Mei-Chuan

“…Pruritus (itch) is a severe side effect associated with the use of drugs as well as hepatic and hematological disorders. Previous studies in rodents suggest…”
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A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates by Ding, Huiping, Czoty, Paul W., Kiguchi, Norikazu, Cami-Kobeci, Gerta, Sukhtankar, Devki D., Nader, Michael A., Husbands, Stephen M., Ko, Mei-Chuan

“…Despite the critical need, no previous research has substantiated safe opioid analgesics without abuse liability in primates. Recent advances in medicinal…”
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GPC-100, a novel CXCR4 antagonist, improves in vivo hematopoietic cell mobilization when combined with propranolol by Sukhtankar, Devki D., Fung, Juan José, Kim, Mi-na, Cayton, Thomas, Chiou, Valerie, Caculitan, Niña G., Zalicki, Piotr, Kim, Sujeong, Jo, Yoonjung, Kim, SoHui, Lee, Jae Min, Choi, Junhee, Mun, SeongGyeong, Chin, Ashley, Jang, Yongdae, Lee, Ji Yeong, Kim, Gowoon, Kim, Eun Hee, Huh, Won-Ki, Jeong, Jae-Yeon, Seen, Dong-Seung, Cardarelli, Pina M.

“…Autologous Stem Cell Transplant (ASCT) is increasingly used to treat hematological malignancies. A key requisite for ASCT is mobilization of hematopoietic stem…”
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Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats by Sukhtankar, Devki D., Lagorio, Carla H., Ko, Mei-Chuan

“…Nociceptin/orphanin FQ peptide (NOP) receptor agonists attenuate morphine-induced conditioned place preference in rodents. However, it is not known whether NOP…”
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Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain by Sukhtankar, Devki D., Lee, Heeseung, Rice, Kenner C., Ko, Mei-Chuan

“…Rationale Carrageenan-induced hyperalgesia is a widely used pain model in rodents. However, characteristics of carrageenan-induced hyperalgesia and effects of…”
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BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates by Kiguchi, Norikazu, Ding, Huiping, Cami-Kobeci, Gerta, Sukhtankar, Devki D, Czoty, Paul W, DeLoid, Heather B, Hsu, Fang-Chi, Toll, Lawrence, Husbands, Stephen M, Ko, Mei-Chuan

“…The marked increase in mis-use of prescription opioids has greatly affected our society. One potential solution is to develop improved analgesics which have…”
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Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/μ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain by Sukhtankar, Devki D, Zaveri, Nurulain T, Husbands, Stephen M, Ko, Mei-Chuan

“…Nociceptin/orphanin FQ peptide receptor (NOP) agonists produce antinociceptive effects in animal models after spinal administration and potentiate μ-opioid…”
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Spinal Functions of B-Type Natriuretic Peptide, Gastrin-Releasing Peptide, and Their Cognate Receptors for Regulating Itch in Mice by Kiguchi, Norikazu, Sukhtankar, Devki D, Ding, Huiping, Tanaka, Ken-ichi, Kishioka, Shiroh, Peters, Christopher M, Ko, Mei-Chuan

“…B-type natriuretic peptide (BNP)-natriuretic peptide receptor A (NPRA) and gastrin-releasing peptide (GRP)-GRP receptor (GRPR) systems contribute to spinal…”
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Pharmacokinetics and Pharmacodynamics of Burixafor Hydrobromide (GPC-100), a Novel C-X-C Chemokine Receptor 4 Antagonist and Mobilizer of Hematopoietic Stem/Progenitor Cells, in Mice and Healthy Subjects by Sukhtankar, Devki D, Chang, Li-Wen, Tsai, Cheng-Yuan, Cardarelli, Pina M, Caculitan, Niña G

“…Adequate mobilization of hematopoietic stem cells (HSCs), especially CD34 cells, is necessary for stem cell transplantation in patients with hematological…”
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Combination of Propranolol and a Novel CXCR4 Antagonist Burixafor (GPC-100) for Enhanced Hematopoietic Cell Mobilization by Sukhtankar, Devki D., Cayton, Thomas, Zalicki, Piotr, Choi, Junhee, Mun, Seonggyeong, Jo, Yoonjung, Kim, Sujeong, Lee, Ji Yeong, Kim, Mi-Na, Chin, Ashley, Ramos, Christian, Huh, Won-Ki, Kim, Sohui, Caculitan, Nina, Jeong, Jae-Yeon, Cardarelli, Josephine M.

“…Burixafor (GPC-100), a novel CXCR4 antagonist, has shown safe and effective mobilization of hematopoietic stem and progenitor cells (HSPC) in a phase I…”
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