Search Results - "Sujan Shresta"

Immune Response to Dengue and Zika by Elong Ngono, Annie, Shresta, Sujan

“…Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV) are human pathogens of global significance. In particular, DENV causes…”
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Cross-Reactive T Cell Immunity to Dengue and Zika Viruses: New Insights Into Vaccine Development by Elong Ngono, Annie, Shresta, Sujan

“…Dengue virus (DENV) is a member of the Flavivirus family that includes Zika virus (ZIKV), West Nile virus, Japanese encephalitis virus, and yellow fever virus…”
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Zika Virus Infects Neural Progenitors in the Adult Mouse Brain and Alters Proliferation by Li, Hongda, Saucedo-Cuevas, Laura, Regla-Nava, Jose A., Chai, Guoliang, Sheets, Nicholas, Tang, William, Terskikh, Alexey V., Shresta, Sujan, Gleeson, Joseph G.

“…Zika virus (ZIKV)-related neuropathology is an important global health concern. Several studies have shown that ZIKV can infect neural stem cells in the…”
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Role of complement in dengue virus infection: protection or pathogenesis? by Shresta, Sujan

“…Dengue viruses (DENV) cause a spectrum of disease in humans, ranging from dengue fever (DF) to a severe, life-threatening syndrome called dengue hemorrhagic…”
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Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge by Wen, Jinsheng, Elong Ngono, Annie, Regla-Nava, Jose Angel, Kim, Kenneth, Gorman, Matthew J., Diamond, Michael S., Shresta, Sujan

“…Zika virus (ZIKV) and dengue virus (DENV) are antigenically related flaviviruses that share cross-reactivity in antibody and T cell responses, and co-circulate…”
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Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease by Zellweger, Raphaël M, Prestwood, Tyler R, Shresta, Sujan

“…Dengue virus (DENV) causes disease ranging from dengue fever (DF), a self-limited febrile illness, to the potentially lethal dengue hemorrhagic fever and…”
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A Mouse Model of Zika Virus Sexual Transmission and Vaginal Viral Replication by Tang, William Weihao, Young, Matthew Perry, Mamidi, Anila, Regla-Nava, Jose Angel, Kim, Kenneth, Shresta, Sujan

“…Case reports of Zika virus (ZIKV) sexual transmission and genital persistence are mounting. Venereal transmission and genital persistence threaten public…”
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Repeated exposure to dengue virus elicits robust cross neutralizing antibodies against Zika virus in residents of Northeastern Thailand by Hattakam, Sararat, Elong Ngono, Annie, McCauley, Melanie, Shresta, Sujan, Yamabhai, Montarop

“…Zika virus (ZIKV) and dengue virus (DENV) are antigenically related mosquito-borne flaviviruses. ZIKV is becoming increasingly prevalent in DENV-endemic…”
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Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8⁺ T cells by Weiskopf, Daniela, Angelo, Michael A, de Azeredo, Elzinandes L, Sidney, John, Greenbaum, Jason A, Fernando, Anira N, Broadwater, Anne, Kolla, Ravi V, De Silva, Aruna D, de Silva, Aravinda M, Mattia, Kimberly A, Doranz, Benjamin J, Grey, Howard M, Shresta, Sujan, Peters, Bjoern, Sette, Alessandro

“…The role of CD8 ⁺ T cells in dengue virus infection and subsequent disease manifestations is not fully understood. According to the original antigenic sin…”
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Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy by Regla-Nava, Jose Angel, Elong Ngono, Annie, Viramontes, Karla M., Huynh, Anh-Thy, Wang, Ying-Ting, Nguyen, Anh-Viet T., Salgado, Rebecca, Mamidi, Anila, Kim, Kenneth, Diamond, Michael S., Shresta, Sujan

“…As Zika virus (ZIKV) emerges into Dengue virus (DENV)-endemic areas, cases of ZIKV infection in DENV-immune pregnant women may rise. Here we show that prior…”
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Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists by Shiryaev, Sergey A., Farhy, Chen, Pinto, Antonella, Huang, Chun-Teng, Simonetti, Nicole, Ngono, Annie Elong, Dewing, Antimone, Shresta, Sujan, Pinkerton, Anthony B., Cieplak, Piotr, Strongin, Alex Y., Terskikh, Alexey V.

“…The recent re-emergence of Zika virus (ZIKV)1, a member of the Flaviviridae family, has become a global emergency. Currently, there are no effective methods of…”
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CD4+ T cells promote humoral immunity and viral control during Zika virus infection by Elong Ngono, Annie, Young, Matthew P, Bunz, Maximilian, Xu, Zhigang, Hattakam, Sararat, Vizcarra, Edward, Regla-Nava, Jose Angel, Tang, William W, Yamabhai, Montarop, Wen, Jinsheng, Shresta, Sujan

“…Several Zika virus (ZIKV) vaccines designed to elicit protective antibody (Ab) responses are currently under rapid development, but the underlying mechanisms…”
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Development of Zika Virus Vaccines by Makhluf, Huda, Shresta, Sujan

“…Zika virus (ZIKV) is a mosquito-borne flavivirus that emerged as a global threat following the most recent outbreak in Brazil in 2015. ZIKV infection of…”
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Murine Model for Dengue Virus-Induced Lethal Disease with Increased Vascular Permeability by SHRESTA, Sujan, SHARAR, Kristin L, PRIGOZHIN, Daniil M, BEATTY, P. Robert, HARRIS, Eva

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The roles of IRF-3 and IRF-7 in innate antiviral immunity against dengue virus by Chen, Hui-Wen, King, Kevin, Tu, Jui, Sanchez, Marisa, Luster, Andrew D, Shresta, Sujan

“…We investigated the roles of IFN regulatory factor (IRF)-3 and IRF-7 in innate antiviral immunity against dengue virus (DENV). Double-deficient…”
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STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor by Perry, Stuart T, Buck, Michael D, Lada, Steven M, Schindler, Christian, Shresta, Sujan

“…Dengue virus (DENV) is a mosquito-borne flavivirus, and symptoms of infection range from asymptomatic to the severe dengue hemorrhagic fever/dengue shock…”
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Role of humoral versus cellular responses induced by a protective dengue vaccine candidate by Zellweger, Raphaël M, Miller, Robyn, Eddy, William E, White, Laura J, Johnston, Robert E, Shresta, Sujan

“…With 2.5 billion people at risk, dengue is a major emerging disease threat and an escalating public health problem worldwide. Dengue virus causes disease…”
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SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus by Branche, Emilie, Wang, Ying-Ting, Viramontes, Karla M., Valls Cuevas, Joan M., Xie, Jialei, Ana-Sosa-Batiz, Fernanda, Shafee, Norazizah, Duttke, Sascha H., McMillan, Rachel E., Clark, Alex E., Nguyen, Michael N., Garretson, Aaron F., Crames, Jan J., Spann, Nathan J., Zhu, Zhe, Rich, Jeremy N., Spector, Deborah H., Benner, Christopher, Shresta, Sujan, Carlin, Aaron F.

“…The emergence of Zika virus (ZIKV) as a global health threat has highlighted the unmet need for ZIKV-specific vaccines and antiviral treatments. ZIKV infects…”
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Human coronavirus OC43-elicited CD4+ T cells protect against SARS-CoV-2 in HLA transgenic mice by dos Santos Alves, Rúbens Prince, Timis, Julia, Miller, Robyn, Valentine, Kristen, Pinto, Paolla Beatriz Almeida, Gonzalez, Andrew, Regla-Nava, Jose Angel, Maule, Erin, Nguyen, Michael N., Shafee, Norazizah, Landeras-Bueno, Sara, Olmedillas, Eduardo, Laffey, Brett, Dobaczewska, Katarzyna, Mikulski, Zbigniew, McArdle, Sara, Leist, Sarah R., Kim, Kenneth, Baric, Ralph S., Ollmann Saphire, Erica, Elong Ngono, Annie, Shresta, Sujan

“…SARS-CoV-2-reactive T cells are detected in some healthy unexposed individuals. Human studies indicate these T cells could be elicited by the common cold…”
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Gamma Interferon (IFN-γ) Receptor Restricts Systemic Dengue Virus Replication and Prevents Paralysis in IFN-α/β Receptor-Deficient Mice by PRESTWOOD, Tyler R, MORAR, Malika M, ZELLWEGER, Raphaël M, MILLER, Robyn, MAY, Monica M, YAUCH, Lauren E, LADA, Steven M, SHRESTA, Sujan

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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