Search Results - "Suhre, K."

Connecting the epigenome, metabolome and proteome for a deeper understanding of disease by Suhre, K., Zaghlool, S.

“…Epigenome‐wide association studies (EWAS) identify genes that are dysregulated by the studied clinical endpoints, thereby indicating potential new diagnostic…”
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The Saliva Metabolome in Association to Oral Health Status by Liebsch, C., Pitchika, V., Pink, C., Samietz, S., Kastenmüller, G., Artati, A., Suhre, K., Adamski, J., Nauck, M., Völzke, H., Friedrich, N., Kocher, T., Holtfreter, B., Pietzner, M.

“…Periodontitis is one of the most prevalent oral diseases worldwide and is caused by multifactorial interactions between host and oral bacteria. Altered…”
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ElNemo: a normal mode web server for protein movement analysis and the generation of templates for molecular replacement by Suhre, Karsten, Sanejouand, Yves-Henri

“…Normal mode analysis (NMA) is a powerful tool for predicting the possible movements of a given macromolecule. It has been shown recently that half of the known…”
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Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma by Ried, J. S., Baurecht, H., Stückler, F., Krumsiek, J., Gieger, C., Heinrich, J., Kabesch, M., Prehn, C., Peters, A., Rodriguez, E., Schulz, H., Strauch, K., Suhre, K., Wang‐Sattler, R., Wichmann, H.‐E., Theis, F. J., Illig, T., Adamski, J., Weidinger, S., Simon, Hans‐Uwe

“…Background Genome‐wide association studies (GWAS) have identified many risk loci for asthma, but effect sizes are small, and in most cases, the biological…”
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Where cancer genomics should go next: a clinician's perspective by Rafii, A, Touboul, C, Al Thani, H, Suhre, K, Malek, J A

“…Large-scale, genomic studies of specific tumors such as The Cancer Genome Atlas have provided a better understanding of the alterations of pathways involved in…”
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Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up by Mook-Kanamori, D. O., Römisch-Margl, W., Kastenmüller, G., Prehn, C., Petersen, A. K., Illig, T., Gieger, C., Wang-Sattler, R., Meisinger, C., Peters, A., Adamski, J., Suhre, K.

“…Background Recently, five branched-chain and aromatic amino acids were shown to be associated with the risk of developing type 2 diabetes (T2D). Aim We set out…”
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Alcohol-induced metabolomic differences in humans by Jaremek, M, Yu, Z, Mangino, M, Mittelstrass, K, Prehn, C, Singmann, P, Xu, T, Dahmen, N, Weinberger, K M, Suhre, K, Peters, A, Döring, A, Hauner, H, Adamski, J, Illig, T, Spector, T D, Wang-Sattler, R

“…Alcohol consumption is one of the world’s major risk factors for disease development. But underlying mechanisms by which moderate-to-heavy alcohol intake…”
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3DCoffee@igs: a web server for combining sequences and structures into a multiple sequence alignment by Poirot, Olivier, Suhre, Karsten, Abergel, Chantal, O'Toole, Eamonn, Notredame, Cedric

“…This paper presents 3DCoffee@igs, a web-based tool dedicated to the computation of high-quality multiple sequence alignments (MSAs). 3D-Coffee makes it…”
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FusionDB: a database for in‐depth analysis of prokaryotic gene fusion events by Suhre, Karsten, Claverie, Jean‐Michel

“…FusionDB (http://igs‐server.cnrs‐mrs.fr/FusionDB/) constitutes a resource dedicated to in‐depth analysis of bacterial and archaeal gene fusion events. Such…”
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Non-truncating LIFR mutation: causal for prominent congenital pain insensitivity phenotype with progressive vertebral destruction? by Elsaid, M.F., Chalhoub, N., Kamel, H., Ehlayel, M., Ibrahim, N., Elsaid, A., Kumar, P., Khalak, H., Ilyin, V.A., Suhre, K., Abdel Aleem, A.

“…We present a Qatari family with two children who displayed a characteristic phenotype of congenital marked pain insensitivity with hypohidrosis and progressive…”
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Comparison of metabolic profiles of acutely ill and short-term weight recovered patients with anorexia nervosa reveals alterations of 33 out of 163 metabolites by Föcker, M, Timmesfeld, N, Scherag, S, Knoll, N, Singmann, P, Wang-Sattler, R, Bühren, K, Schwarte, R, Egberts, K, Fleischhaker, C, Adamski, J, Illig, T, Suhre, K, Albayrak, Ö, Hinney, A, Herpertz-Dahlmann, B, Hebebrand, J

“…Abstract Starvation represents an extreme physiological state and entails numerous endocrine and metabolic adaptations. The large-scale application of…”
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CaspR: a web server for automated molecular replacement using homology modelling by Claude, Jean-Baptiste, Suhre, Karsten, Notredame, Cédric, Claverie, Jean-Michel, Abergel, Chantal

“…Molecular replacement (MR) is the method of choice for X-ray crystallography structure determination when structural homologues are available in the Protein…”
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Annotation of bacterial genomes using improved phylogenomic profiles by Enault, F., Suhre, K., Abergel, C., Poirot, O., Claverie, J.-M.

“…Motivation: Phylogenomic profiling is a large-scale comparative genomic method used to infer protein function from evolutionary information first described in…”
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Genetics meets proteomics: perspectives for large population-based studies by Suhre, Karsten, McCarthy, Mark I., Schwenk, Jochen M.

“…Proteomic analysis of cells, tissues and body fluids has generated valuable insights into the complex processes influencing human biology. Proteins represent…”
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Development of a reduced chemical scheme for use in mesoscale meteorological models by Crassier, V, Suhre, K, Tulet, P, Rosset, R

“…A new Regional Lumped Atmospheric Chemical Scheme (ReLACS) is introduced. This mechanism is intended to be valid for clean to polluted conditions. ReLACS is…”
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Phydbac2: improved inference of gene function using interactive phylogenomic profiling and chromosomal location analysis by Enault, François, Suhre, Karsten, Poirot, Olivier, Abergel, Chantal, Claverie, Jean-Michel

“…Phydbac (phylogenomic display of bacterial genes) implemented a method of phylogenomic profiling using a distance measure based on normalized BLAST scores…”
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Mixing of boundary layer and upper tropospheric ozone during a deep convective event over Western Europe by Tulet, P, Suhre, K, Mari, C, Solmon, F, Rosset, R

“…Typically, during summer over Europe, pollution episodes in the boundary layer are interspersed with deep convective events which significantly redistribute…”
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MassTRIX: mass translator into pathways by Suhre, Karsten, Schmitt-Kopplin, Philippe

“…Recent technical advances in mass spectrometry (MS) have brought the field of metabolomics to a point where large numbers of metabolites from numerous…”
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Internal and external mixing in atmospheric aerosols by coagulation: Impact on the optical and hygroscopic properties of the sulphate-soot system by Fassi-Fihri, A., Suhre, K., Rosset, R.

“…A sectional aerosol model is used to study the impact of internal/external aerosol mixing on the optical and hygroscopic properties of two-component aerosol…”
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Overview of the Meso-NH model version 5.4 and its applications by Lac, Christine, Chaboureau, Jean-Pierre, Masson, Valéry, Pinty, Jean-Pierre, Tulet, Pierre, Escobar, Juan, Leriche, Maud, Barthe, Christelle, Aouizerats, Benjamin, Augros, Clotilde, Aumond, Pierre, Auguste, Franck, Bechtold, Peter, Berthet, Sarah, Bielli, Soline, Bosseur, Frédéric, Caumont, Olivier, Cohard, Jean-Martial, Colin, Jeanne, Couvreux, Fleur, Cuxart, Joan, Delautier, Gaëlle, Dauhut, Thibaut, Ducrocq, Véronique, Filippi, Jean-Baptiste, Gazen, Didier, Geoffroy, Olivier, Gheusi, François, Honnert, Rachel, Lafore, Jean-Philippe, Lebeaupin Brossier, Cindy, Libois, Quentin, Lunet, Thibaut, Mari, Céline, Maric, Tomislav, Mascart, Patrick, Mogé, Maxime, Molinié, Gilles, Nuissier, Olivier, Pantillon, Florian, Peyrillé, Philippe, Pergaud, Julien, Perraud, Emilie, Pianezze, Joris, Redelsperger, Jean-Luc, Ricard, Didier, Richard, Evelyne, Riette, Sébastien, Rodier, Quentin, Schoetter, Robert, Seyfried, Léo, Stein, Joël, Suhre, Karsten, Taufour, Marie, Thouron, Odile, Turner, Sandra, Verrelle, Antoine, Vié, Benoît, Visentin, Florian, Vionnet, Vincent, Wautelet, Philippe

“…This paper presents the Meso-NH model version 5.4. Meso-NH is an atmospheric non hydrostatic research model that is applied to a broad range of resolutions,…”
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