Search Results - "Suhovskih, Anastasia V."
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Proteoglycans as potential microenvironmental biomarkers for colon cancer
Published in Cell and tissue research (01-09-2015)“…Glycosylation changes occur widely in colon tumours, suggesting glycosylated molecules as potential biomarkers for colon cancer diagnostics. In this study,…”
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Multiple Irradiation Affects Cellular and Extracellular Components of the Mouse Brain Tissue and Adhesion and Proliferation of Glioblastoma Cells in Experimental System In Vivo
Published in International journal of molecular sciences (12-12-2021)“…Intensive adjuvant radiotherapy (RT) is a standard treatment for glioblastoma multiforme (GBM) patients; however, its effect on the normal brain tissue remains…”
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Chemoradiotherapy Increases Intratumor Heterogeneity of HPSE Expression in the Relapsed Glioblastoma Tumors
Published in International journal of molecular sciences (14-02-2020)“…Adjuvant chemoradiotherapy is a standard treatment option for glioblastoma multiforme (GBM). Despite intensive care, recurrent tumors developed during the…”
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Chemotherapy-Induced Degradation of Glycosylated Components of the Brain Extracellular Matrix Promotes Glioblastoma Relapse Development in an Animal Model
Published in Frontiers in oncology (19-07-2021)“…Adjuvant chemotherapy with temozolomide (TMZ) is an intrinsic part of glioblastoma multiforme (GBM) therapy targeted to eliminate residual GBM cells. Despite…”
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Conventional Anti-glioblastoma Chemotherapy Affects Proteoglycan Composition of Brain Extracellular Matrix in Rat Experimental Model in vivo
Published in Frontiers in pharmacology (02-10-2018)“…Temozolomide (TMZ) is a conventional chemotherapy drug for adjuvant treatment of glioblastoma multiforme (GBM), often accompanied by dexamethasone (DXM) to…”
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Long-Term Exposure to Temozolomide Affects Locomotor Activity and Cartilage Structure of Elderly Experimental Rats
Published in Biomedicines (26-11-2020)“…Chemotherapy with temozolomide (TMZ) is an essential part of anticancer therapy of various malignant tumours; however, its long-term effects on patients'…”
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Transcriptional Activity of Heparan Sulfate Biosynthetic Machinery is Specifically Impaired in Benign Prostate Hyperplasia and Prostate Cancer
Published in Frontiers in oncology (01-01-2014)“…Heparan sulfates (HSs) are key components of mammalian cells surface and extracellular matrix. Structure and composition of HS, generated by HS-biosynthetic…”
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Chondroitin sulfate content and decorin expression in glioblastoma are associated with proliferative activity of glioma cells and disease prognosis
Published in Cell and tissue research (2020)“…Chondroitin sulfate proteoglycans (CSPGs) are important components of brain extracellular matrix (ECM), although their contribution in gliomagenesis remains…”
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Suitability of RNALater solution as a tissue-preserving reagent for immunohistochemical analysis
Published in Histochemistry and cell biology (01-09-2019)“…Histological and immunohistochemical studies require high-quality paraffin blocks, where proper fixation of tissue samples with formalin is a key point…”
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Heparan sulfate accumulation and perlecan/HSPG2 up-regulation in tumour tissue predict low relapse-free survival for patients with glioblastoma
Published in Histochemistry and cell biology (01-03-2018)“…Glycosaminoglycans are major components of brain extracellular matrix (ECM), although heparan sulfate (HS) contribution in brain physiology and carcinogenesis…”
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Prostate cancer cells specifically reorganize epithelial cell-fibroblast communication through proteoglycan and junction pathways
Published in Cell adhesion & migration (02-01-2017)“…Microenvironment and stromal fibroblasts are able to inhibit tumor cell proliferation both through secreted signaling molecules and direct cell-cell…”
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Tissue-specificity of heparan sulfate biosynthetic machinery in cancer
Published in Cell adhesion & migration (2015)“…Heparan sulfate (HS) proteoglycans are key components of cell microenvironment and fine structure of their polysaccharide HS chains plays an important role in…”
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Proteoglycan Expression in Normal Human Prostate Tissue and Prostate Cancer
Published in ISRN oncology (2013)“…Proteoglycans (PGs) are expressed on the cell surface and extracellular matrix of all mammalian cells and tissues, playing an important role in cell-cell and…”
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