Search Results - "Suh, KweeHyun"

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  1. 1
    Structure Characterization of Degradation Products of Drug Candidate HM30571 by UPLC‐QTOF‐MS and In Silico Toxicity Prediction

    Structure Characterization of Degradation Products of Drug Candidate HM30571 by UPLC‐QTOF‐MS and In Silico Toxicity Prediction by Bang, Hyojeong, Whang, Wankyunn, Bang, Keukchan, Lee, Eunyoung, Kim, Eunyoung, Ahn, Younggil, Suh, Kweehyun

    Published in Bulletin of the Korean Chemical Society (01-01-2020)
    “…Procedure of forced degradation study, structure elucidation of degradation products by UPLC‐QTOF‐MS and in silico toxicity prediction…”
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  2. 2
    A Novel and Potent EZH1/2 Dual Inhibitor HM97594 for the Treatment of Hematological Malignancies

    A Novel and Potent EZH1/2 Dual Inhibitor HM97594 for the Treatment of Hematological Malignancies by Jung, Seung Hyun, Hong, DongJin, Kim, SeoHee, Hwang, Jiyoung, Byun, Jooyun, Lee, Miyoung, Koo, Kyounghwa, Lee, Gunwoo, Song, TaeHun, Lim, SunYoung, Kim, Yu-Yon, Park, Hyunjin, Bak, Yesol, Ko, Myoungsil, Jung, Sunyoung, Han, Yuri, Ahn, YoungGil, Kim, YoungHoon, Suh, KweeHyun

    Published in Blood (13-11-2019)
    “…In mammals, either enhancer of zeste homologue 2 (EZH2) or its homolog EZH1 functions as the catalytic subunit of polycomb repressive complex 2 (PRC2), and…”
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  3. 3
    Metabolite identification of a new tyrosine kinase inhibitor, HM781-36B, and a pharmacokinetic study by liquid chromatography/tandem mass spectrometry

    Metabolite identification of a new tyrosine kinase inhibitor, HM781-36B, and a pharmacokinetic study by liquid chromatography/tandem mass spectrometry by Kim, Eunyoung, Kim, Hankyong, Suh, Kweehyun, Kwon, Sechang, Lee, Gwansun, Park, Na Hyun, Hong, Jongki

    Published in Rapid communications in mass spectrometry (15-06-2013)
    “…RATIONALE HM781‐36B (1‐[4‐[4‐(3,4‐dichloro‐2‐fluorophenylamino)‐7‐methoxyquinazolin‐6‐yloxy]‐piperidin‐1‐yl]prop‐2‐en‐1‐one hydrochloride) is a new anticancer…”
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  4. 4
    Abstract 804: Antitumor activity of the potent and novel FLT3 inhibitor HM43239 in acute myeloid leukemia

    Abstract 804: Antitumor activity of the potent and novel FLT3 inhibitor HM43239 in acute myeloid leukemia by Lee, Miyoung, Ha, Young Eun, Moon, Mi Jin, Byun, Joo-Yun, Yu, HyunKyung, Kang, SeokJong, Lee, JaeHo, Lee, Kyuhang, Kim, Eunkyung, Kim, Eunyoung, Lee, Ho Jeong, Kim, YoungHoon, Ahn, YoungGil, Suh, KweeHyun, Kim, Sun-Jin

    Published in Cancer research (Chicago, Ill.) (01-07-2018)
    “…Introduction: Acute myeloid leukemia (AML) with FMS-like tyrosine kinase 3 (FLT3) mutations is associated with poor prognosis with a high risk of relapse after…”
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  5. 5
    Abstract 4871: Antitumor activity of novel reversible LSD1 inhibitor, HM97211 in preclinical models of SCLC

    Abstract 4871: Antitumor activity of novel reversible LSD1 inhibitor, HM97211 in preclinical models of SCLC by Bae, InHwan, Kim, JiSook, Park, ChangHee, Kim, Hyeongki, Gwangmog, Namgoong, Byun, Joo-Yun, Hong, Seokhyun, Song, Teahun, Lee, JaeHo, Lee, Kyuhang, Ko, Myoungsil, Kim, Cheolkyung, Lee, YoungMi, Lee, Ho Jeong, Kim, YoungHoon, Ahn, YoungGil, Suh, KweeHyun, Kim, Sun-Jin

    Published in Cancer research (Chicago, Ill.) (01-07-2018)
    “…Introduction: Global changes in the epigenetic landscape are known as the hallmark in cancer and the histone demethylase Lysine-specific demethylase 1 (LSD1)…”
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  6. 6
    Abstract 4780: A novel, potent and selective FGFR4 inhibitor, HM81422 in hepatocellular carcinoma with FGFR4-driven pathway activation

    Abstract 4780: A novel, potent and selective FGFR4 inhibitor, HM81422 in hepatocellular carcinoma with FGFR4-driven pathway activation by Lee, JaeHo, Kang, Hyunjeong, Koo, Kyounghwa, Ha, Youngeun, Lim, Sun Young, Byun, Joo-Yun, Yu, Hyunkyung, Song, Taehun, Lee, Moonsub, Jung, Seung Hyun, Kim, Taewoo, Bang, Hyojeong, Kim, Eunyoung, Kang, Jahoon, Lee, Ho Jeong, Kim, YoungHoon, Ahn, YoungGil, Suh, KweeHyun, Kim, Sun-Jin

    Published in Cancer research (Chicago, Ill.) (01-07-2018)
    “…Introduction: Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer and the second most frequent cause of cancer-related death, however, treatment…”
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  7. 7
    Abstract 2606: Antitumor activity of the selective RAF inhibitor HM95573 in melanoma

    Abstract 2606: Antitumor activity of the selective RAF inhibitor HM95573 in melanoma by Bae, InHwan, Ahn, YoungGil, GwangMo, Namgoong, Kim, SuHyeon, Song, JiYeon, Song, TaeHun, Lee, JaeHo, Lee, KyuHang, Lee, Young-Mi, Kim, YoungHoon, Suh, KweeHyun

    Published in Cancer research (Chicago, Ill.) (01-08-2015)
    “…The mitogen-activated protein kinase (MAPK) pathway is particularly important for the survival and proliferation of tumor cells. Activation of the MAPK pathway…”
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