Search Results - "Sugur, Harsha S."
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MN1 rearrangement in astroblastoma: study of eight cases and review of literature
Published in Brain tumor pathology (01-07-2019)“…Astroblastomas are unique tumours with unresolved issues in terms of their origin, molecular biology, clinical behaviour, and response to treatment. To…”
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Differential gene expression in peritumoral brain zone of glioblastoma: role of SERPINA3 in promoting invasion, stemness and radioresistance of glioma cells and association with poor patient prognosis and recurrence
Published in Journal of neuro-oncology (01-03-2021)“…Purpose Glioblastoma (GBM) is a highly invasive tumor. Despite advances in treatment modalities, tumor recurrence is common, seen mainly in the peritumoral…”
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Chitinase 3-Like 2: A Novel Biomarker Expressed in Peritumoral Brain Zone of Glioblastoma is associated With tumor recurrence and Poor Patient Prognosis
Published in American journal of clinical pathology (01-10-2022)“…Objectives: We aimed to evaluate the expression pattern of chitinase 3-like 2 (CHI3L2) in the tumor core and peritumoral brain zone (PBZ) of newly diagnosed…”
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Chitinase 3-Like 2
Published in American journal of clinical pathology (06-10-2022)“…Abstract Objectives We aimed to evaluate the expression pattern of chitinase 3-like 2 (CHI3L2) in the tumor core and peritumoral brain zone (PBZ) of newly…”
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IRX1 is a novel gene, overexpressed in high-grade IDH-mutant astrocytomas
Published in Pathology, research and practice (01-05-2023)“…IDH-mutant astrocytomas include CNS WHO grade 2 (A2), grade 3 (A3) and grade 4 (A4), of which A3 and A4 are high-grade. A3 has a heterogenous clinical outcome…”
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Prognostic significance of histomolecular subgroups of adult anaplastic (WHO Grade III) gliomas: applying the 'integrated' diagnosis approach
Published in Journal of clinical pathology (01-08-2016)“…Anaplastic gliomas (AGs; WHO Grade III) include anaplastic astrocytoma (AA), anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA) and are…”
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Alpha Internexin: A Surrogate Marker for 1p/19q Codeletion and Prognostic Marker in Anaplastic (WHO grade III) Gliomas
Published in Neurology India (01-07-2020)“…Background: The WHO 2016 classification of diffuse gliomas has incorporated molecular markers isocitrate dehydrogenase (IDH) gene mutations (IDHmut) and…”
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DDDR-41. A GENOME-WIDE CRISPR/CAS9 SCREEN IN GLIOBLASTOMA STEM CELLS UNVEILS SYNTHETIC LETHAL INTERACTIONS AND RESISTANCE MECHANISMS OF JIN001, A BLOOD-BRAIN BARRIER-PENETRANT HSP90 INHIBITOR
Published in Neuro-oncology (Charlottesville, Va.) (11-11-2024)“…Glioblastomas (GBMs) are aggressive brain tumors characterized by extensive genetic heterogeneity and therapeutic resistance. Heat shock protein 90 (Hsp90) is…”
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