Search Results - "Sugur, Harsha"

MN1 rearrangement in astroblastoma: study of eight cases and review of literature by Mhatre, Radhika, Sugur, Harsha S., Nandeesh, B. N., Chickabasaviah, Yasha, Saini, J., Santosh, Vani

“…Astroblastomas are unique tumours with unresolved issues in terms of their origin, molecular biology, clinical behaviour, and response to treatment. To…”
Get full text

Differential gene expression in peritumoral brain zone of glioblastoma: role of SERPINA3 in promoting invasion, stemness and radioresistance of glioma cells and association with poor patient prognosis and recurrence by Nimbalkar, Vidya P., Kruthika, Banavathy S., Sravya, Palavalasa, Rao, Shilpa, Sugur, Harsha S., Verma, Brijesh Kumar, Chickabasaviah, Yasha T., Arivazhagan, Arimappamagan, Kondaiah, Paturu, Santosh, Vani

“…Purpose Glioblastoma (GBM) is a highly invasive tumor. Despite advances in treatment modalities, tumor recurrence is common, seen mainly in the peritumoral…”
Get full text

Chitinase 3-Like 2: A Novel Biomarker Expressed in Peritumoral Brain Zone of Glioblastoma is associated With tumor recurrence and Poor Patient Prognosis by Nimbalkar, Vidya P, Kruthika, Banavathy S, Sravya, Palavalasa, Rao, Shilpa, Sugur, Harsha S, Chickabasaviah, Yasha T, Somanna, Sampath, Arivazhagan, Arimappamagan, Kondaiah, Paturu, Santosh, Vani

“…Objectives: We aimed to evaluate the expression pattern of chitinase 3-like 2 (CHI3L2) in the tumor core and peritumoral brain zone (PBZ) of newly diagnosed…”
Get full text

Chitinase 3-Like 2 by Nimbalkar, Vidya P, Kruthika, Banavathy S, Sravya, Palavalasa, Rao, Shilpa, Sugur, Harsha S, Chickabasaviah, Yasha T, Somanna, Sampath, Arivazhagan, Arimappamagan, Kondaiah, Paturu, Santosh, Vani

“…Abstract Objectives We aimed to evaluate the expression pattern of chitinase 3-like 2 (CHI3L2) in the tumor core and peritumoral brain zone (PBZ) of newly…”
Get full text

IRX1 is a novel gene, overexpressed in high-grade IDH-mutant astrocytomas by Sugur, Harsha S., Rao, Shilpa, Sravya, Palavalasa, Athul Menon, K., Arivazhagan, Arimappamagan, Mehta, Bhupesh, Santosh, Vani

“…IDH-mutant astrocytomas include CNS WHO grade 2 (A2), grade 3 (A3) and grade 4 (A4), of which A3 and A4 are high-grade. A3 has a heterogenous clinical outcome…”
Get full text

Prognostic significance of histomolecular subgroups of adult anaplastic (WHO Grade III) gliomas: applying the 'integrated' diagnosis approach by Rajmohan, K S, Sugur, Harsha S, Shwetha, S D, Ramesh, Arvind, Thennarasu, Kandavel, Pandey, Paritosh, Arivazhagan, Arimappamagan, Santosh, Vani

“…Anaplastic gliomas (AGs; WHO Grade III) include anaplastic astrocytoma (AA), anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA) and are…”
Get more information

Alpha Internexin: A Surrogate Marker for 1p/19q Codeletion and Prognostic Marker in Anaplastic (WHO grade III) Gliomas by Rajmohan, K, Sugur, Harsha, Shwetha, S, Pandey, Paritosh, Arivazhagan, Arimappamagan, Santosh, Vani

“…Background: The WHO 2016 classification of diffuse gliomas has incorporated molecular markers isocitrate dehydrogenase (IDH) gene mutations (IDHmut) and…”
Get full text

Central nervous system high grade neuroepithelial tumor with BCOR immunopositivity: Is there a molecular heterogeneity? by Rao, Shilpa, Mitra, Saikat, Sugur, Harsha, Vazhayil, Vikas, Rao, B. Ravi Mohan, Annayappa, Santosh Kumar, Nandeesh, B. N., Yasha, T. C., Santosh, Vani

“…Central nervous system high grade neuroepithelial tumor – BCOR altered is a newly defined entity which is characterised by internal tandem duplication (ITD) in…”
Get full text

DDDR-30. ENHANCED CHEMO AND RADIO-SENSITIZATION OF GLIOMAS BY HSP90 INHIBITION WITH JIN-001, A NOVEL BLOOD-BRAIN BARRIER PENETRANT HSP90 INHIBITOR by Xu, Jihong, Sugur, Harsha S, Sharma, Pratibha, Huo, Longfei, Dasgupta, Pushan, Chen, Xiaohua, Seah, Ethan, Sampath, Deepa, Puduvalli, Vinay K

Get full text

MYCN amplification in spinal ependymoma: A five‐year retrospective study by Rao, Shilpa, Sugur, Harsha, Konar, Subhas, Arivazhagan, Arimappamagan, Santosh, Vani

“…Spinal ependymoma with MYCN amplification is a newly recognized type of spinal ependymoma that is known to be associated with poor prognosis. Available studies…”
Get full text

DDDR-41. A GENOME-WIDE CRISPR/CAS9 SCREEN IN GLIOBLASTOMA STEM CELLS UNVEILS SYNTHETIC LETHAL INTERACTIONS AND RESISTANCE MECHANISMS OF JIN001, A BLOOD-BRAIN BARRIER-PENETRANT HSP90 INHIBITOR by Chen, Xiaohua, Anvar, Nazanin Esmaeili, Colic, Medina, Xu, Jihong, Liang, Jiyong, Sharma, Pratibha, Huo, Longfei, Sugur, Harsha S, Hart, Traver, Puduvalli, Vinay K

“…Glioblastomas (GBMs) are aggressive brain tumors characterized by extensive genetic heterogeneity and therapeutic resistance. Heat shock protein 90 (Hsp90) is…”
Get full text

Spinal astroblastoma: a rare tumour in an unusual location by Rao, Shilpa, Nufina, T. A., Sugur, Harsha, Arumalla, Kirit, Devi, B. Indira, Santosh, Vani

“…Astroblastomas are central nervous system tumours with unknown cell of origin and clinical behaviour. These tumours occur most commonly in cerebral hemispheres…”
Get full text

Medulloblastoma: Distinctive Histo-Molecular Correlation with Clinical Profile, Radiologic Characteristics, and Surgical Outcome by Narayan, Vinayak, Sugur, Harsha, Jaiswal, Janhvi, Arvinda, H R, Arivazhagan, Arimappamagan, Somanna, Sampath, Santosh, Vani

“…Medulloblastoma (MB) is a heterogenous tumor, and the prognosis is influenced by various clinical, histological, and molecular factors. The aim of the study is…”
Get more information

Low mitochondrial DNA copy number is associated with poor prognosis and treatment resistance in glioblastoma by Sravya, Palavalasa, Nimbalkar, Vidya Prasad, Kanuri, Nandaki Nag, Sugur, Harsha, Verma, Brijesh Kumar, Kundu, Paramita, Rao, Shilpa, Uday Krishna, A.S., Somanna, Sampath, Kondaiah, Paturu, Arivazhagan, Arimappamagan, Santosh, Vani

“…•Mitochondrial DNA (mtDNA) copy number is a prognostic marker in glioblastoma (GBM).•Low mtDNA copy number in GBM is associated with poor prognosis.•Recurrent…”
Get full text

RDNA-11. LOW MITOCHONDRIAL DNA CONTENT INDUCES TREATMENT RESISTANCE AND CONFERS POOR PROGNOSIS IN GLIOBLASTOMA by Sravya, Palavalasa, Nimbalkar, Vidya, Kanuri, Nandaki, Sugur, Harsha, Rao, Shilpa, Somanna, Sampath, Kondaiah, Paturu, Arimappamagan, Arivazhagan, Santosh, Vani

“…Abstract BACKGROUND Investigation of mitochondrial DNA (mtDNA) content in glioblastoma has gathered speed in recent years. Our study focusses on the effect of…”
Get full text

H3K27M, IDH1, and ATRX expression in pediatric GBM and their clinical and prognostic significance by Uppar, Alok Mohan, Sugur, Harsha, Prabhuraj, A. R., Rao, M. Bhaskara, Devi, B. Indira, Sampath, S., Arivazhagan, A., Santosh, Vani

“…Purpose Pediatric glioblastoma (pGBM) tumors have been identified as an entity distinct and different from the adult variety of GBM not only with respect to…”
Get full text

Proteomic profiling of medulloblastoma reveals novel proteins differentially expressed within each molecular subgroup by Narayan, Vinayak, Jaiswal, Janhvi, Sugur, Harsha, SD, Shwetha, Rao, Shilpa, Chatterjee, Aditi, Gowda, Harsha, A, Arivazhagan, Somanna, Sampath, Santosh, Vani

“…•Novel biomarkers and signalling pathways of medulloblastoma (MB) are identified.•The top upregulated proteins are GFAP, PMEL, FBN2, SYNGR2, MAGEA10, and…”
Get full text

Chromosomal aberrations in chordoid meningioma - An analysis by Sugur, Harsha, Shastry, Arun, Sadashiva, Nishant, Srinivas, Dwarakanath, Santosh, Vani, Somanna, Sampath

“…Introduction: Chordoid meningiomas (CMs) are a rare subgroup of tumors, accounting for approximately 0.5% of all meningiomas. These tumors correspond to World…”
Get full text