Search Results - "Sugrue, Kelsey F."

Overcoming Temozolomide Resistance in Glioblastoma via Dual Inhibition of NAD+ Biosynthesis and Base Excision Repair by GOELLNER, Eva M, GRIMME, Bradford, BROWN, Ashley R, LIN, Ying-Chih, WANG, Xiao-Hong, SUGRUE, Kelsey F, MITCHELL, Leah, TRIVEDI, Ram N, TANG, Jiang-Bo, SOBOL, Robert W

“…Glioblastoma multiforme (GBM) is a devastating brain tumor with poor prognosis and low median survival time. Standard treatment includes radiation and…”
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Mechanism for generation of left isomerism in Ccdc40 mutant embryos by Sugrue, Kelsey F, Zohn, Irene E

“…Leftward fluid flow in the mouse node is generated by cilia and is critical for initiating asymmetry of the left-right axis. Coiled-coil domain containing-40…”
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The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch by Sugrue, Kelsey F, Sarkar, Anjali A, Leatherbury, Linda, Zohn, Irene E

“…The development of the aortic arch is a complex process that involves remodeling of the bilaterally symmetrical pharyngeal arch arteries (PAAs) into the mature…”
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Reduced maternal vitamin A status increases the incidence of normal aortic arch variants by Sugrue, Kelsey F., Zohn, Irene E.

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HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β by Fang, Qingming, Inanc, Burcu, Schamus, Sandy, Wang, Xiao-hong, Wei, Leizhen, Brown, Ashley R., Svilar, David, Sugrue, Kelsey F., Goellner, Eva M., Zeng, Xuemei, Yates, Nathan A., Lan, Li, Vens, Conchita, Sobol, Robert W.

“…Cellular DNA repair processes are crucial to maintain genome stability and integrity. In DNA base excision repair, a tight heterodimer complex formed by DNA…”
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Reduced maternal vitamin A status increases the incidence of normal aortic arch variants by Sugrue, Kelsey F., Zohn, Irene E.

“…Summary While common in the general population, the developmental origins of “normal” anatomic variants of the aortic arch remain unknown. Aortic arch…”
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Supt20 is required for development of the axial skeleton by Warrier, Sunita, Nuwayhid, Samer, Sabatino, Julia A., Sugrue, Kelsey F., Zohn, Irene E.

“…Somitogenesis and subsequent axial skeletal development is regulated by the interaction of pathways that determine the periodicity of somite formation,…”
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Abnormal labyrinthine zone in the Hectd1 -null placenta by Sarkar, Anjali A, Sabatino, Julia A, Sugrue, Kelsey F, Zohn, Irene E

“…Abstract Introduction The labyrinthine zone of the placenta is where exchange of nutrients and waste occurs between maternal and fetal circulations. Proper…”
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Variations in maternal vitamin A intake modifies phenotypes in a mouse model of 22q11.2 deletion syndrome by Yitsege, Gelila, Stokes, Bethany A., Sabatino, Julia A., Sugrue, Kelsey F., Banyai, Gabor, Paronett, Elizabeth M., Karpinski, Beverly A., Maynard, Thomas M., LaMantia, Anthony‐S., Zohn, Irene E.

“…Background Vitamin A regulates patterning of the pharyngeal arches, cranial nerves, and hindbrain that are essential for feeding and swallowing. In the LgDel…”
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Molecular Mechanisms and Environmental Influences Underlying Heart Development by Sugrue, Kelsey F

“…Heart development is an intricate process that involves complex morphological events controlled by transcriptional/signaling networks. Any alterations in these…”
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HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase [beta] by Fang, Qingming, Inanc, Burcu, Schamus, Sandy, Wang, Xiao-hong, Wei, Leizhen, Brown, Ashley R, Svilar, David, Sugrue, Kelsey F, Goellner, Eva M, Zeng, Xuemei, Yates, Nathan A, Lan, Li, Vens, Conchita, Sobol, Robert W

“…Cellular DNA repair processes are crucial to maintain genome stability and integrity. In DNA base excision repair, a tight heterodimer complex formed by DNA…”
Get full text