Search Results - "Sugrue, Jamie A"

Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection by Townsend, Liam, Dyer, Adam H, Jones, Karen, Dunne, Jean, Mooney, Aoife, Gaffney, Fiona, O'Connor, Laura, Leavy, Deirdre, O'Brien, Kate, Dowds, Joanne, Sugrue, Jamie A, Hopkins, David, Martin-Loeches, Ignacio, Ni Cheallaigh, Cliona, Nadarajan, Parthiban, McLaughlin, Anne Marie, Bourke, Nollaig M, Bergin, Colm, O'Farrelly, Cliona, Bannan, Ciaran, Conlon, Niall

“…Fatigue is a common symptom in those presenting with symptomatic COVID-19 infection. However, it is unknown if COVID-19 results in persistent fatigue in those…”
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Type I Interferon and the Spectrum of Susceptibility to Viral Infection and Autoimmune Disease: A Shared Genomic Signature by Sugrue, Jamie A, Bourke, Nollaig M, O'Farrelly, Cliona

“…Type I interferons (IFN-I) and their cognate receptor, the IFNAR1/2 heterodimer, are critical components of the innate immune system in humans. They have been…”
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Uncovering Resistance to Hepatitis C Virus Infection: Scientific Contributions and Unanswered Questions in the Irish Anti-D Cohort by Sugrue, Jamie A, O'Farrelly, Cliona

“…Infections caused inadvertently during clinical intervention provide valuable insight into the spectrum of human responses to viruses. Delivery of hepatitis C…”
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Systems vaccinology studies – achievements and future potential by Sugrue, Jamie A., Duffy, Darragh

“…Human immune responses to vaccination are variable both within and between populations. Systems vaccinology, which is the application of multi-omics…”
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Innate antiviral immunity and immunometabolism in hepatocytes by Sularea, Vasile Mihai, Sugrue, Jamie A, O’Farrelly, Cliona

“…The human liver mediates whole-body metabolism, systemic inflammation and responses to hepatotropic pathogens. Hepatocytes, the most abundant cell type of the…”
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Enhanced TLR3 responsiveness in hepatitis C virus resistant women from the Irish anti-D cohort by Sugrue, Jamie A., Posseme, Céline, Tan, Ziyang, Pou, Christian, Charbit, Bruno, Bondet, Vincent, Bourke, Nollaig M., Brodin, Petter, Duffy, Darragh, O’Farrelly, Cliona

“…Natural resistance to infection is an overlooked outcome after hepatitis C virus (HCV) exposure. Between 1977 and 1979, 1,200 Rhesus D-negative Irish women…”
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Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation by Posseme, Celine, Llibre, Alba, Charbit, Bruno, Bondet, Vincent, Rouilly, Vincent, Saint-André, Violaine, Boussier, Jeremy, Bergstedt, Jacob, Smith, Nikaïa, Townsend, Liam, Sugrue, Jamie A, Ní Cheallaigh, Clíona, Conlon, Niall, Rotival, Maxime, Kobor, Michael S, Mottez, Estelle, Pol, Stanislas, Patin, Etienne, Albert, Matthew L, Quintana-Murci, Lluis, Duffy, Darragh

“…The interleukin-12 (IL-12) family comprises the only heterodimeric cytokines mediating diverse functional effects. We previously reported a striking bimodal…”
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Rhesus negative males have an enhanced IFNγ-mediated immune response to influenza A virus by Sugrue, Jamie A., Smith, Megan, Posseme, Celine, Charbit, Bruno, Bourke, Nollaig M., Duffy, Darragh, O’Farrelly, Cliona

“…The Rhesus D antigen (RhD) has been associated with susceptibility to several viral infections. Reports suggest that RhD-negative individuals are better…”
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