Search Results - "Sugrue, J"

Bio-On-Magnetic-Beads (BOMB): Open platform for high-throughput nucleic acid extraction and manipulation by Oberacker, Phil, Stepper, Peter, Bond, Donna M, Höhn, Sven, Focken, Jule, Meyer, Vivien, Schelle, Luca, Sugrue, Victoria J, Jeunen, Gert-Jan, Moser, Tim, Hore, Steven R, von Meyenn, Ferdinand, Hipp, Katharina, Hore, Timothy A, Jurkowski, Tomasz P

“…Current molecular biology laboratories rely heavily on the purification and manipulation of nucleic acids. Yet, commonly used centrifuge- and column-based…”
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Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci by Sugrue, Victoria J, Zoller, Joseph Alan, Narayan, Pritika, Lu, Ake T, Ortega-Recalde, Oscar J, Grant, Matthew J, Bawden, C Simon, Rudiger, Skye R, Haghani, Amin, Bond, Donna M, Hore, Reuben R, Garratt, Michael, Sears, Karen E, Wang, Nan, Yang, Xiangdong William, Snell, Russell G, Hore, Timothy A, Horvath, Steve

“…In mammals, females generally live longer than males. Nevertheless, the mechanisms underpinning sex-dependent longevity are currently unclear. Epigenetic…”
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Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly by Ludwig, Alexander, Nguyen, Tra Huong, Leong, Daniel, Ravi, Laxmi Iyer, Tan, Boon Huan, Sandin, Sara, Sugrue, Richard J

“…Respiratory syncytial virus (RSV) is an enveloped virus that assembles into filamentous virus particles on the surface of infected cells. Morphogenesis of RSV…”
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Pregnancy reference intervals and exertion and breathlessness ratings for the six minute walk test in healthy nulliparous people by Francis, Alaina R., Sugrue, Tahila J., Dennis, Alicia T.

“…The Six Minute Walk Test (6MWT) is a simple, non-invasive, well-validated test that assesses cardiorespiratory fitness however is rarely used in pregnant…”
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Human nasal epithelial cells derived from multiple subjects exhibit differential responses to H3N2 influenza virus infection in vitro by Yan, Yan, PhD, Tan, Kai Sen, BSc, Li, Chunwei, PhD, Tran, Thai, PhD, Chao, Siew Shuen, MD, Sugrue, Richard J., PhD, Shi, Li, MD, PhD, Chow, Vincent T., MD, PhD, Wang, De-Yun, MD, PhD

“…[...]to elucidate the sequential and spatiotemporal reactions of pathogen sensors to respiratory viruses documented in different experimental…”
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Benchmarking selected computational gene network growing tools in context of virus-host interactions by Taye, Biruhalem, Vaz, Candida, Tanavde, Vivek, Kuznetsov, Vladimir A., Eisenhaber, Frank, Sugrue, Richard J., Maurer-Stroh, Sebastian

“…Several available online tools provide network growing functions where an algorithm utilizing different data sources suggests additional genes/proteins that…”
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Activation of type I and III interferon signalling pathways occurs in lung epithelial cells infected with low pathogenic avian influenza viruses by Sutejo, Richard, Yeo, Dawn S, Myaing, Myint Zu, Hui, Chen, Xia, Jiajia, Ko, Debbie, Cheung, Peter C F, Tan, Boon-Huan, Sugrue, Richard J

“…The host response to the low pathogenic avian influenza (LPAI) H5N2, H5N3 and H9N2 viruses were examined in A549, MDCK, and CEF cells using a systems-based…”
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Systems-based approach to examine the cytokine responses in primary mouse lung macrophages infected with low pathogenic avian Influenza virus circulating in South East Asia by Taye, Biruhalem, Chen, Hui, Myaing, Myint Zu, Tan, Boon Huan, Maurer-Stroh, Sebastian, Sugrue, Richard J

“…Influenza A virus (IAV) is a major public health concern, being responsible for the death of approximately half a million people each year. Zoonotic…”
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Inter-Species Host Gene Expression Differences in Response to Human and Avian Influenza A Virus Strains by Taye, Biruhalem, Yeo, Dawn, Lee, Raphael Tze Chuen, Tan, Boon Huan, Sugrue, Richard J, Maurer-Stroh, Sebastian

“…Low pathogenic avian influenza (LPAI) viruses are a source of sporadic human infections and could also contribute to future pandemic outbreaks but little is…”
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Increased hydroxymethylglutaryl coenzyme A reductase activity during respiratory syncytial virus infection mediates actin dependent inter-cellular virus transmission by Ravi, Laxmi Iyer, Liang, Li, Wong, Pui San, Brown, Gaie, Tan, Boon Huan, Sugrue, Richard J.

“…•RSV particles mature as virus filaments.•Virus transmission occurs by virus filaments.•RSV filament formation is inhibited by lovastatin.•Lovastatin inhibits…”
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A System Based-Approach to Examine Cytokine Response in Poxvirus-Infected Macrophages by Wong, Pui-San, Sutejo, Richard, Chen, Hui, Ng, Sock-Hoon, Sugrue, Richard J, Tan, Boon-Huan

“…The poxviruses are large, linear, double-stranded DNA viruses about 130 to 230 kbp, that have an animal origin and evolved to infect a wide host range. Variola…”
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Ultrastructural analysis of the interaction between F-actin and respiratory syncytial virus during virus assembly by Jeffree, Chris E, Brown, Gaie, Aitken, Jim, Su-Yin, Dawn Yeo, Tan, Boon-Huan, Sugrue, Richard J

“…Abstract During respiratory syncytial virus (RSV) infection there is a close physical interaction between the filamentous actin (F-actin) and the virus,…”
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Evidence for an association between heat shock protein 70 and the respiratory syncytial virus polymerase complex within lipid-raft membranes during virus infection by Brown, Gaie, Rixon, Helen W. McL, Steel, John, McDonald, Terence P., Pitt, Andrew R., Graham, Susan, Sugrue, Richard J.

“…In this report, the interaction between respiratory syncytial virus (RSV) and heat shock protein 70 (HSP70) was examined. Although no significant increase in…”
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A System Based-Approach to Examine Host Response during Infection with Influenza A Virus Subtype H7N9 in Human and Avian Cells by Taye, Biruhalem, Chen, Hui, Yeo, Dawn Su-Yin, Seah, Shirley Gek-Kheng, Wong, Michelle Su-Yen, Sugrue, Richard J, Tan, Boon-Huan

“…Although the influenza A virus H7N9 subtype circulates within several avian species, it can also infect humans with a severe disease outcome. To better…”
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Impaired Nuclear Export of the Ribonucleoprotein Complex and Virus-Induced Cytotoxicity Combine to Restrict Propagation of the A/Duck/Malaysia/02/2001 (H9N2) Virus in Human Airway Cells by Kumar, Sriram, Yeo, Dawn, Harur Muralidharan, Nisha, Lai, Soak Kuan, Tong, Cathlyn, Tan, Boon Huan, Sugrue, Richard J

“…In humans, (A549) cells impaired H9N2 virus nuclear export of the ribonucleoprotein (RNP) complex contrasted with the early and efficient nuclear export of the…”
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Whole genome characterization of non-tissue culture adapted HRSV strains in severely infected children by Kumaria, Rajni, Iyer, Laxmi Ravi, Hibberd, Martin L, Simões, Eric A F, Sugrue, Richard J

“…Human respiratory syncytial virus (HRSV) is the most important virus causing lower respiratory infection in young children. The complete genetic…”
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Analysis of the interaction between respiratory syncytial virus and lipid-rafts in Hep2 cells during infection by Brown, Gaie, Jeffree, Chris E., McDonald, Terence, McL. Rixon, Helen W., Aitken, James D., Sugrue, Richard J.

“…The assembly of respiratory syncytial virus (RSV) in lipid-rafts was examined in Hep2 cells. Confocal and electron microscopy showed that during RSV assembly,…”
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The RSV F and G glycoproteins interact to form a complex on the surface of infected cells by Low, Kit-Wei, Tan, Timothy, Ng, Ken, Tan, Boon-Huan, Sugrue, Richard J.

“…In this study, the interaction between the respiratory syncytial virus (RSV) fusion (F) protein, attachment (G) protein, and small hydrophobic (SH) proteins…”
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Evidence that selective changes in the lipid composition of raft-membranes occur during respiratory syncytial virus infection by Yeo, Dawn Su-Yin, Chan, Robin, Brown, Gaie, Ying, Li, Sutejo, Richard, Aitken, Jim, Tan, Boon-Huan, Wenk, Markus R, Sugrue, Richard J

“…Abstract We examined the structure of lipid-raft membranes in respiratory syncytial virus infected cells. Cholesterol depletion studies using…”
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Safety and efficacy of an electrothermal bipolar vessel sealing device in sealing and division of the inferior mesenteric vessels in minimally invasive colorectal surgery by Pai, A., Sugrue, J., Bibi, S., Melich, G., Marecik, S., Prasad, L. M., Park, J.

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