Search Results - "Sugiyama, Aruto"

High-throughput cytotoxicity and antigen-binding assay for screening small bispecific antibodies without purification by Sugiyama, Aruto, Umetsu, Mitsuo, Nakazawa, Hikaru, Niide, Teppei, Asano, Ryutaro, Hattori, Takamitsu, Kumagai, Izumi

“…The cytotoxicity of T cell-recruiting antibodies with their potential to damage late-stage tumor masses is critically dependent on their structural and…”
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A semi high-throughput method for screening small bispecific antibodies with high cytotoxicity by Sugiyama, Aruto, Umetsu, Mitsuo, Nakazawa, Hikaru, Niide, Teppei, Onodera, Tomoko, Hosokawa, Katsuhiro, Hattori, Shuhei, Asano, Ryutaro, Kumagai, Izumi

“…Small bispecific antibodies that induce T-cell–mediated cytotoxicity have the potential to damage late-stage tumor masses to a clinically relevant degree, but…”
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Association behavior and control of the quality of cancer therapeutic bispecific diabodies expressed in Escherichia coli by Nakazawa, Hikaru, Onodera-Sugano, Tomoko, Sugiyama, Aruto, Tanaka, Yoshikazu, Hattori, Takamitsu, Niide, Teppei, Ogata, Hiromi, Asano, Ryutaro, Kumagai, Izumi, Umetsu, Mitsuo

“…•Nearly half the LH diabody fraction and all the HL fraction were in inactive form.•Diabody fraction components changed dynamically with time.•The association…”
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Recent research advances on non-linear phenomena in various biosystems by Tamaru, Yutaka, Nakanishi, Shuji, Tanaka, Kenya, Umetsu, Mitsuo, Nakazawa, Hikaru, Sugiyama, Aruto, Ito, Tomoyuki, Shimokawa, Naofumi, Takagi, Masahiro

“…All biological phenomena can be classified as open, dissipative and non-linear. Moreover, the most typical phenomena are associated with non-linearity,…”
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Generation of camelid VHH bispecific constructs via in-cell intein-mediated protein trans-splicing by Shibuya, Yuki, Haga, Natsuki, Asano, Ryutaro, Nakazawa, Hikaru, Hattori, Takamitsu, Takeda, Daisuke, Sugiyama, Aruto, Kurotani, Reiko, Kumagai, Izumi, Umetsu, Mitsuo, Makabe, Koki

“…Production of various combinations of bispecific variable domain of heavy chain of heavy chain-only antibody (VHH) constructs to evaluate their therapeutic…”
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Compact Seahorse‐Shaped T Cell–Activating Antibody for Cancer Therapy by Fujii, Hiroto, Tanaka, Yoshikazu, Nakazawa, Hikaru, Sugiyama, Aruto, Manabe, Noriyoshi, Shinoda, Akira, Shimizu, Nobutaka, Hattori, Takamitsu, Hosokawa, Katsuhiro, Sujino, Takuma, Ito, Tomoyuki, Niide, Teppei, Asano, Ryutaro, Kumagai, Izumi, Umetsu, Mitsuo

“…The vast information available on hierarchically structured proteins enables the creation of novel proteins with customized functions through the assembly of…”
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