Search Results - "Sugimoto, Michihiko"

MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells by Ishiguro, Kei-ichiro, Matsuura, Kumi, Tani, Naoki, Takeda, Naoki, Usuki, Shingo, Yamane, Mariko, Sugimoto, Michihiko, Fujimura, Sayoko, Hosokawa, Mihoko, Chuma, Shinichiro, Ko, Minoru S.H., Araki, Kimi, Niwa, Hitoshi

“…The mechanisms regulating meiotic initiation in mammals are enigmatic. It is known that retinoic acid (RA) signaling plays a pivotal role during meiotic…”
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X chromosome reactivation initiates in nascent primordial germ cells in mice by Sugimoto, Michihiko, Abe, Kuniya

“…During primordial germ cell (PGC) development, epigenetic reprogramming events represented by X chromosome reactivation and erasure of genomic imprinting are…”
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Developmental genetics of the mouse t-complex by Sugimoto, Michihiko

“…The proximal third of mouse chromosome 17 is known as the t-complex. The t-haplotype is a variant form of this region containing four tandem inversions…”
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Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination by Takemoto, Kazumasa, Tani, Naoki, Takada-Horisawa, Yuki, Fujimura, Sayoko, Tanno, Nobuhiro, Yamane, Mariko, Okamura, Kaho, Sugimoto, Michihiko, Araki, Kimi, Ishiguro, Kei-ichiro

“…Meiotic recombination is critical for genetic exchange and generation of chiasmata that ensures faithful chromosome segregation during meiosis I. Meiotic…”
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Universal Surface Biotinylation: a simple, versatile and cost-effective sample multiplexing method for single-cell RNA-seq analysis by Sugimoto, Michihiko, Tada, Yuhki, Shichino, Shigeyuki, Koyamatsu, Saeko, Tsumaki, Noriyuki, Abe, Kuniya

“…Recent advances in single-cell analysis technology have made it possible to analyse tens of thousands of cells at a time. In addition, sample multiplexing…”
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RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos by Matoba, Shogo, Inoue, Kimiko, Kohda, Takashi, Sugimoto, Michihiko, Mizutani, Eiji, Ogonuki, Narumi, Nakamura, Toshinobu, Abe, Kuniya, Nakano, Toru, Ishino, Fumitoshi, Ogura, Atsuo

“…Cloning mammals by somatic cell nuclear transfer (SCNT) is highly inefficient. Most SCNT-generated embryos die after implantation because of unidentified,…”
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Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models by Ariyasu, Daisuke, Kubo, Emika, Higa, Daisuke, Shibata, Shinsuke, Takaoka, Yutaka, Sugimoto, Michihiko, Imaizumi, Kazunori, Hasegawa, Tomonobu, Araki, Kimi

“…Isolated growth hormone deficiency type II (IGHD2) is mainly caused by heterozygous splice-site mutations in intron 3 of the GH1 gene. A dominant-negative…”
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Mouse Genetics: ONKO CHISHIN -study the old, to understand the new by Sugimoto, Michihiko

“…Following the rediscovery of Mendel's laws, research fields based on genetics began to grow dramatically. Simultaneously, the development of inbred strains of…”
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New evidence confirms that the mitochondrial bottleneck is generated without reduction of mitochondrial DNA content in early primordial germ cells of mice by Cao, Liqin, Shitara, Hiroshi, Sugimoto, Michihiko, Hayashi, Jun-Ichi, Abe, Kuniya, Yonekawa, Hiromichi

“…In mammals, observations of rapid shifts in mitochondrial DNA (mtDNA) variants between generations have led to the creation of the bottleneck theory for the…”
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WS4-1 The role of Vps52 as a regulator of pluripotent stem cell differentiation through cell-cell interactions by SUGIMOTO Michihiko

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De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency by Yagi, Masaki, Kabata, Mio, Ukai, Tomoyo, Ohta, Sho, Tanaka, Akito, Shimada, Yui, Sugimoto, Michihiko, Araki, Kimi, Okita, Keisuke, Woltjen, Knut, Hochedlinger, Konrad, Yamamoto, Takuya, Yamada, Yasuhiro

“…CpG islands (CGIs) including those at imprinting control regions (ICRs) are protected from de novo methylation in somatic cells. However, many cancers often…”
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Whole-exome sequencing reveals known and novel variants in a cohort of intracranial vertebral-basilar artery dissection (IVAD) by Wang, Kun, Zhao, Sen, Zhang, Qianqian, Yuan, Jian, Liu, Jiaqi, Ding, Xinghuan, Song, Xiaofei, Lin, Jiachen, Du, Renqian, Zhou, Yangzhong, Sugimoto, Michihiko, Chen, Weisheng, Yuan, Bo, Liu, Jian, Yan, Zihui, Liu, Bowen, Zhang, Yisen, Li, Xiaoxin, Niu, Yuchen, Long, Bo, Shen, Yiping, Zhang, Shuyang, Abe, Kuniya, Su, Jianzhong, Wu, Zhihong, Wu, Nan, Liu, Pengfei, Yang, Xinjian

“…Intracranial vertebral-basilar artery dissection (IVAD) is an arterial disorder leading to life-threatening consequences. Genetic factors are known to be…”
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A simple and robust method for establishing homogeneous mouse epiblast stem cell lines by wnt inhibition by Sugimoto, Michihiko, Kondo, Masayo, Koga, Yumiko, Shiura, Hirosuke, Ikeda, Rieko, Hirose, Michiko, Ogura, Atsuo, Murakami, Ayumi, Yoshiki, Atsushi, Chuva de Sousa Lopes, Susana M, Abe, Kuniya

“…Epiblast stem cells (EpiSCs) are pluripotent stem cells derived from epiblasts of postimplantation mouse embryos, and thus provide a useful model for studying…”
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RNAi-mediated Knockdown of Xist Does Not Rescue the Impaired Development of Female Cloned Mouse Embryos by OIKAWA, Mami, MATOBA, Shogo, INOUE, Kimiko, KAMIMURA, Satoshi, HIROSE, Michiko, OGONUKI, Narumi, SHIURA, Hirosuke, SUGIMOTO, Michihiko, ABE, Kuniya, ISHINO, Fumitoshi, OGURA, Atsuo

“…In mice, one of the major epigenetic errors associated with somatic cell nuclear transfer (SCNT) is ectopic expression of Xist during the preimplantation…”
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Cellular Dynamics of Mouse Trophoblast Stem Cells: Identification of a Persistent Stem Cell Type1 by Motomura, Kaori, Oikawa, Mami, Hirose, Michiko, Honda, Arata, Togayachi, Sumie, Miyoshi, Hiroyuki, Ohinata, Yasuhide, Sugimoto, Michihiko, Abe, Kuniya, Inoue, Kimiko, Ogura, Atsuo

“…Mouse trophoblast stem cells (TSCs) proliferate indefinitely in vitro, despite their highly heterogeneous nature. In this study, we sought to characterize TSC…”
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Differences and similarities in the developmental status of embryo-derived stem cells and primordial germ cells revealed by global expression profiling by Mise, Nathan, Fuchikami, Takuya, Sugimoto, Michihiko, Kobayakawa, Satoru, Ike, Fumio, Ogawa, Takehiko, Tada, Takashi, Kanaya, Shigehiko, Noce, Toshiaki, Abe, Kuniya

“…Embryonic germ-line cells are unipotent cells that give rise to either sperm or oocytes. However, pluripotent stem cells can be derived from primordial germ…”
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W11-3 Positional cloning of a responsible gene for the mouse t-complex recessive lethal mutation -A role of Vps52 gene as a differentiation regulator of pluripotential cells during mammalian early embryogenesis by SUGIMOTO Michihiko, ABE Kuniya

“…The mouse t-complex is a variant form of the proximal third of chromosome 17, in which a number of developmental mutations are mapped. Homozygous mutant for…”
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1C-09 Role of Vps52 as a key regulator for differentiation of pluripotent stem cells revealed by the analysis of tw5 mutant mice by SUGIMOTO Michihiko, KONKO Masayo, ABE Kuniya

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Molecular Identification of tw5: Vps52 Promotes Pluripotential Cell Differentiation through Cell–Cell Interactions by Sugimoto, Michihiko, Kondo, Masayo, Hirose, Michiko, Suzuki, Misao, Mekada, Kazuyuki, Abe, Takaya, Kiyonari, Hiroshi, Ogura, Atsuo, Takagi, Nobuo, Artzt, Karen, Abe, Kuniya

“…After implantation, pluripotent epiblasts are converted to embryonic ectoderm through cell–cell interactions that significantly change the transcriptional and…”
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Large-scale production of growing oocytes in vitro from neonatal mouse ovaries by Honda, Arata, Hirose, Michiko, Inoue, Kimiko, Hiura, Hitoshi, Miki, Hiromi, Ogonuki, Narumi, Sugimoto, Michihiko, Abe, Kuniya, Kanatsu-Shinohara, Mito, Kono, Tomohiro, Shinohara, Takashi, Ogura, Atsuo

“…Although fetal or neonatal mammalian ovaries contain many non-growing oocytes within primordial follicles, most degenerate and only a few contribute to the…”
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