Search Results - "Suggate, Michael J."

Recent Developments in the Transfer of Chirality within Enolate Alkylation Reactions by Eames, Jason, Suggate, Michael J.

“…Remarkable asymmetric induction is observed in the alkylation of enolates derived from enantiomerically pure amides, even though these enolates seem to have no…”
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The use of quasi-enantiomeric isotopomers as chiral probes for determining stereoisomeric purity by Eames, Jason, Suggate, Michael J.

“…This review discusses the use of chiral isotopomers, in particular the use of quasi‐enantiomeric isotopomers as novel chiral probes for determination of…”
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Enantioselective Protonation of a Lithium Enolate Derived from 2-Methyl-1-tetralone Using Chiral Sulfonamides by Coumbarides, Gregory S, Eames, Jason, Scheuermann, J. Erik W, Sibbons, Kevin F, Suggate, Michael J, Watkinson, Michael

“…The synthesis of enantiomerically enriched (R)-2-methyl-1-tetralone (1) with 77% e.e. was achieved through protonation of its lithium enolate (3) using a…”
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Investigations into the Regioselective C-Deuteration of Acyclic and Exocyclic Enolates by Eames, Jason, Coumbarides, Gregory S., Suggate, Michael J., Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteration of a series of related acyclic and exocyclic enolates derived from substituted aryl ketones. We…”
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Investigations into the C-deuteriation of aryl alkyl ketones using urea as a pro-base in the presence of a deuterium donor by Coumbarides, Gregory S., Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteriation of a series of enolates derived from the deprotonation of aryl alkyl ketones using dilithiated urea…”
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Investigations into the C-deuteriation of silyl enol ethers derived from aryl alkyl ketones by Buksha, Svitlana, Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteriation of a series of silyl enol ethers derived from aryl alkyl ketones using deuterium (D2) gas as the…”
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Probing the regioselective C-deuteriation of lithium enolates derived from 2-methyl-tetralone in the presence of substituted tertiary amines by Begum, Mothia, Chavda, Sameer, Coumbarides, Gregory S., Dingan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteriation of 2‐methyl‐tetralone using a series of D‐sources and tertiary amines as potential mediators. The…”
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On the specific rotation of deuterium-containing isotopomers of 2-dimethylaminocyclohexyl-1-trimethylammonium iodide by Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Suggate, Michael J.

“…The specific rotation of a variety of differential isotopomers is reported. The difference in their specific rotation appears to be greater than their…”
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Investigations into the C-deuteriation of enol acetates derived from aryl alkyl ketones by Buksha, Svitlana, Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteriation of a series of enol acetates (derived from the aryl alkyl ketones) using molecular deuterium as the…”
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Investigations into the enantioselective C-protonation of prostereogenic enolate(s) derived from N, N′-diisopropyl-2-phenylpropanamide using suicide C-based proton sources by Coumbarides, Gregory S., Eames, Jason, Ghilagaber, Stephanos, Suggate, Michael J.

“…[Display omitted] The synthesis of enantiomerically enriched (−)-( R)- N, N′-diisopropyl-2-phenylpropanamide was achieved in up to 69% enantiomeric excess by…”
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Investigations into theC-deuteriation of aryl alkyl ketones using urea as a pro-base in the presence of a deuterium donor by Coumbarides, Gregory S., Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

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Reversal of enantioselectivity on protonation of enol(ate)s derived from 2-methyl-1-tetralone using C 2-symmetric sulfonamides by Boyd, Ewan, Coumbarides, Gregory S., Eames, Jason, Hay, Alastair, Jones, Ray V.H., Stenson, Rachel A., Suggate, Michael J.

“…[Display omitted] The synthesis of enantiomerically enriched ( R)-2-methyl-1-tetralone 1 (64% e.e.) was achieved through protonation of its lithium enolate 3…”
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Synthesis and derivatisation of N, N′-trisubstituted 1,2-diamines derived from (1 R,2 R)-1,2-diaminocyclohexane by Boyd, Ewan, Coumbarides, Gregory S., Eames, Jason, Jones, Ray V.H., Stenson, Rachel A., Suggate, Michael J.

“…[Display omitted] The synthesis of N, N′-trisubstituted 1,2-diamines can be achieved by simple reduction of an aminal derived from (1 R,2…”
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Synthesis of N, N′-disubstituted cyclic 1,2-diamines derived from (1 R,2 R)-1,2-diaminocyclohexane by Boyd, Ewan, Coumbarides, Gregory S., Eames, Jason, Jones, Ray V.H., Motevalli, Majid, Stenson, Rachel A., Suggate, Michael J.

“…[Display omitted] The synthesis of N, N′-unsymmetrically tetrasubstituted cyclic 1,2-diamines derived from (1 R,2 R)-diaminocyclohexane is reported. We comment…”
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Reversal of enantioselectivity on protonation of enol(ate)s derived from 2-methyl-1-tetralone using C2-symmetric sulfonamides by Boyd, Ewan, Coumbarides, Gregory S., Eames, Jason, Hay, Alastair, Jones, Ray V.H., Stenson, Rachel A., Suggate, Michael J.

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An efficient synthesis of tetrasubstituted cyclohexyl-1,2-diamines by Arjan, Hitesh, Boyd, Ewan, Coumbarides, Gregory S., Eames, Jason, H. Jones, Ray V., Stenson, Rachel A., Suggate, Michael J.

“…[Display omitted] The synthesis of symmetrically tetrasubstituted diamines derived from the ( R, R)-cyclohexyl-1,2-diamine is reported. We comment on the…”
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Investigations into theC-deuteriation of silyl enol ethers derived from aryl alkyl ketones by Buksha, Svitlana, Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

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Probing the regioselectiveC-deuteriation of lithium enolates derived from 2-methyl-tetralone in the presence of substituted tertiary amines by Begum, Mothia, Chavda, Sameer, Coumbarides, Gregory S., Dingan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

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Investigations into the regioselective C-deuteriation of enolates derived from 2-methyl tetralone using piperidine-d11 by Coumbarides, Gregory S., Eames, Jason, Suggate, Michael J.

“…Results are reported on the regioselective C‐deuteriation of 2‐methyl tetralone using piperidine‐d11 as a deuterium source. The results presented further aid…”
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Investigations into the regioselective C ‐deuteriation of enolates derived from 2‐methyl tetralone using piperidine‐ d 11 by Coumbarides, Gregory S., Eames, Jason, Suggate, Michael J.

“…Results are reported on the regioselective C ‐deuteriation of 2‐methyl tetralone using piperidine‐ d 11 as a deuterium source. The results presented further…”
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