Search Results - "Sugawara, Waka"

The methylation status of RASSF1A promoter predicts responsiveness to chemotherapy and eventual cure in hepatoblastoma patients by Honda, Shohei, Haruta, Masayuki, Sugawara, Waka, Sasaki, Fumiaki, Ohira, Miki, Matsunaga, Tadashi, Yamaoka, Hiroaki, Horie, Hiroshi, Ohnuma, Naomi, Nakagawara, Akira, Hiyama, Eiso, Todo, Satoru, Kaneko, Yasuhiko

“…Despite the progress of therapy, outcomes of advanced hepatoblastoma patients who are refractory to standard preoperative chemotherapy remain unsatisfactory…”
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Yolk sac tumor but not seminoma or teratoma is associated with abnormal epigenetic reprogramming pathway and shows frequent hypermethylation of various tumor suppressor genes by Furukawa, Shinsuke, Haruta, Masayuki, Arai, Yasuhito, Honda, Shohei, Ohshima, Junjiro, Sugawara, Waka, Kageyama, Yukio, Higashi, Yotsuo, Nishida, Kazunori, Tsunematsu, Yukiko, Nakadate, Hisaya, Ishii, Masahiro, Kaneko, Yasuhiko

“…Germ cell tumors (GCTs) are thought to arise from primordial germ cells (PGCs) that undergo epigenetic reprogramming: erasure of the somatic imprint in the…”
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Efficacy and pharmacokinetics of imatinib mesylate in a child with chronic myeloid leukemia by Sugawara, Waka, Endo, Mikiya, Nakatuji, Yukie, Hosokawa, Takahide, Chida, Shoichi

“…A 6-year-old girl with chronic myeloid leukemia (CML) was treated with imatinib 230 mg/m2/day and its pharmacokinetics were investigated. The patient had a…”
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Association of germline or somatic TP53 missense mutation with oncogene amplification in tumors developed in patients with Li-Fraumeni or Li-Fraumeni-like syndrome by Sugawara, Waka, Arai, Yasuhito, Kasai, Fumio, Fujiwara, Yuiko, Haruta, Masayuki, Hosaka, Rie, Nishida, Kazunori, Kurosumi, Masashi, Kobayashi, Yasuhito, Akagi, Kiwamu, Kaneko, Yasuhiko

“…Germline TP53 mutations are found in Li‐Fraumeni syndrome (LFS) patients, predisposed to soft tissue sarcoma and other malignancies. The mutations and…”
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Promoter hypermethylation of the RASSF1A gene predicts the poor outcome of patients with hepatoblastoma by Sugawara, Waka, Haruta, Masayuki, Sasaki, Fumiaki, Watanabe, Naoki, Tsunematsu, Yukiko, Kikuta, Atsushi, Kaneko, Yasuhiko

“…Background Despite the progress of therapy, about 25% of patients with hepatoblastoma succumb to the disease. Prognostic factors, as well as improved…”
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Duplication of paternal IGF2 or loss of maternal IGF2 imprinting occurs in half of Wilms tumors with various structural WT1 abnormalities by Haruta, Masayuki, Arai, Yasuhito, Sugawara, Waka, Watanabe, Naoki, Honda, Shohei, Ohshima, Junjiro, Soejima, Hidenobu, Nakadate, Hisaya, Okita, Hajime, Hata, Jun-ichi, Fukuzawa, Masahiro, Kaneko, Yasuhiko

“…The WT1 gene essential for the embryonic kidney development is mutated in 15–25% of Wilms tumors (WTs). To clarify whether genetic subtypes of WT1…”
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Association of 11q loss, trisomy 12, and possible 16q loss with loss of imprinting of insulin-like growth factor-II in Wilms tumor by Watanabe, Naoki, Nakadate, Hisaya, Haruta, Masayuki, Sugawara, Waka, Sasaki, Fumiaki, Tsunematsu, Yukiko, Kikuta, Atsushi, Fukuzawa, Masahiro, Okita, Hajime, Hata, Jun-ichi, Soejima, Hidenobu, Kaneko, Yasuhiko

“…We evaluated the WT1 and IGF2 status and performed chromosome and/or comparative genomic hybridization analysis in 43 tumor samples from patients with Wilms…”
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Consensus JH Gene Probes with Conjugated 3′-Minor Groove Binder for Monitoring Minimal Residual Disease in Acute Lymphoblastic Leukemia by Uchiyama, Michihiro, Maesawa, Chihaya, Yashima-Abo, Akiko, Tarusawa, Mitsu, Endo, Mikiya, Sugawara, Waka, Chida, Shoichi, Onodera, Shima, Tsukushi, Yasuhiko, Ishida, Yoji, Tsuchiya, Shigeru, Masuda, Tomoyuki

“…Several approaches for the detection of minimal residual disease (MRD) in childhood acute lymphoblastic leukemia (ALL) have shown the importance of determining…”
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