Search Results - "Sugawara, Shigeki"

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    Sialic acid-binding lectin from bullfrog eggs inhibits human malignant mesothelioma cell growth in vitro and in vivo by Tatsuta, Takeo, Satoh, Toshiyuki, Sugawara, Shigeki, Hara, Akiyoshi, Hosono, Masahiro

    Published in PloS one (03-01-2018)
    “…Malignant mesothelioma is an aggressive cancer that results from exposure to asbestos. The therapeutic options for this type of cancer are limited; therefore,…”
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    Journal Article
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    Catfish Egg Lectin Enhances the Cytotoxicity of Sunitinib on Gb3-Expressing Renal Cancer Cells by Ito, Jun, Sugawara, Shigeki, Tatsuta, Takeo, Hosono, Masahiro, Sato, Makoto

    Published in Biomedicines (01-08-2023)
    “…Metastatic renal cell carcinoma (RCC) is not sufficiently responsive to anticancer drugs, and thus, developing new drugs for advanced RCC remains vital. We…”
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    Sialic Acid-Binding Lectin from Bullfrog Eggs Exhibits an Anti-Tumor Effect Against Breast Cancer Cells Including Triple-Negative Phenotype Cells by Tatsuta, Takeo, Sato, Shoko, Sato, Toshiyuki, Sugawara, Shigeki, Suzuki, Tsuneyoshi, Hara, Akiyoshi, Hosono, Masahiro

    Published in Molecules (Basel, Switzerland) (21-10-2018)
    “…Sialic acid-binding lectin from eggs (cSBL) is a multifunctional protein that has lectin and ribonuclease activity. In this study, the anti-tumor activities of…”
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    Catfish egg lectin affects influx and efflux rates of sunitinib in human cervical carcinoma HeLa cells by Sugawara, Shigeki, Takayanagi, Madoka, Honda, Shota, Tatsuta, Takeo, Fujii, Yuki, Ozeki, Yasuhiro, Ito, Jun, Sato, Makoto, Hosono, and Masahiro

    Published in Glycobiology (Oxford) (28-09-2020)
    “…Abstract New treatment protocols are aiming to reduce the dose of the multitargeted tyrosine kinase inhibitor sunitinib, as sunitinib elicits many adverse…”
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    Synergistic anti-tumor effect of bullfrog sialic acid-binding lectin and pemetrexed in malignant mesothelioma by Satoh, Toshiyuki, Tatsuta, Takeo, Sugawara, Shigeki, Hara, Akiyoshi, Hosono, Masahiro

    Published in Oncotarget (27-06-2017)
    “…Malignant mesothelioma is an aggressive cancer with limited therapeutic options. Sialic acid-binding lectin isolated from Rana catesbeiana oocytes (cSBL) is a…”
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    Journal Article
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    Sialidase NEU3 Contributes to the Invasiveness of Bladder Cancer by Tatsuta, Takeo, Ito, Jun, Yamamoto, Koji, Sugawara, Shigeki, Hosono, Masahiro, Sato, Makoto, Miyagi, Taeko

    Published in Biomedicines (01-01-2024)
    “…Bladder cancer is the 10th most commonly diagnosed cancer worldwide. The current standard treatment for advanced bladder cancer is neoadjuvant cisplatin…”
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    RNase activity of sialic acid-binding lectin from bullfrog eggs drives antitumor effect via the activation of p38 MAPK to caspase-3/7 signaling pathway in human breast cancer cells by Kariya, Yukiko, Tatsuta, Takeo, Sugawara, Shigeki, Kariya, Yoshinobu, Nitta, Kazuo, Hosono, Masahiro

    Published in International journal of oncology (01-10-2016)
    “…Sialic acid-binding lectin obtained from bullfrog eggs (SBL) induces cell death in cancer cells but not in normal cells. This antitumor effect is mediated…”
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    Sialic acid-binding lectin (leczyme) induces caspase-dependent apoptosis-mediated mitochondrial perturbation in Jurkat cells by Tatsuta, Takeo, Hosono, Masahiro, Sugawara, Shigeki, Kariya, Yukiko, Ogawa, Yukiko, Hakomori, Senitiroh, Nitta, Kazuo

    Published in International journal of oncology (01-11-2013)
    “…Sialic acid binding lectin (SBL) isolated from Rana catesbeiana oocytes is a multifunctional protein which has lectin activity, ribonuclease activity and…”
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    Involvement of ER stress in apoptosis induced by sialic acid-binding lectin (leczyme) from bullfrog eggs by TATSUTA, TAKEO, HOSONO, MASAHIRO, MIURA, YUKI, SUGAWARA, SHIGEKI, KARIYA, YUKIKO, HAKOMORI, SENITIROH, NITTA, KAZUO

    Published in International journal of oncology (01-12-2013)
    “…Sialic-acid binding lectin (SBL) isolated from bullfrog (Rana catesbeiana) oocytes is a multifunctional protein which has lectin activity, ribonuclease…”
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    Journal Article
  12. 12

    Catfish rhamnose-binding lectin induces G0/1 cell cycle arrest in Burkitt’s lymphoma cells via membrane surface Gb3 by Sugawara, Shigeki, Im, Changhun, Kawano, Tasuku, Tatsuta, Takeo, Koide, Yasuhiro, Yamamoto, Daiki, Ozeki, Yasuhiro, Nitta, Kazuo, Hosono, Masahiro

    Published in Glycoconjugate journal (01-02-2017)
    “…Silurus asotus egg lectin (SAL), an α-galactoside-binding protein isolated from the eggs of catfish, is a member of the rhamnose-binding lectin family that…”
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    Downregulation of Hsp70 inhibits apoptosis induced by sialic acid-binding lectin (leczyme) by TATSUTA, TAKEO, HOSONO, MASAHIRO, OGAWA, YUKIKO, INAGE, KYOKO, SUGAWARA, SHIGEKI, NITTA, KAZUO

    Published in Oncology reports (01-01-2014)
    “…Heat shock proteins (Hsps) are molecular chaperones that maintain homeostasis of organisms. In regards to the Hsps, many studies have investigated the…”
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    Leczyme : A New Candidate Drug for Cancer Therapy by Tatsuta, Takeo, Sugawara, Shigeki, Takahashi, Kohta, Ogawa, Yukiko, Hosono, Masahiro, Nitta, Kazuo

    Published in BioMed research international (01-01-2014)
    “…Sialic acid-binding lectin (SBL), isolated from oocytes of Rana catesbeiana, is leczyme and has both lectin and ribonuclease (RNase) activities. A remarkable…”
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    Binding profiles and cytokine-inducing effects of fish rhamnose-binding lectins on Burkitt’s lymphoma Raji cells by Hosono, Masahiro, Sugawara, Shigeki, Matsuda, Atsushi, Tatsuta, Takeo, Koide, Yasuhiro, Hasan, Imtiaji, Ozeki, Yasuhiro, Nitta, Kazuo

    Published in Fish physiology and biochemistry (01-10-2014)
    “…Rhamnose-binding lectin (RBL) is one of the animal lectin categories which take part in the innate immune responses of fish. Osmerus lanceolatus lectin (OLL)…”
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    Cancer-selective induction of apoptosis by leczyme by Tatsuta, Takeo, Sugawara, Shigeki, Takahashi, Kohta, Ogawa, Yukiko, Hosono, Masahiro, Nitta, Kazuo

    Published in Frontiers in oncology (01-01-2014)
    “…Sialic acid-binding lectin (SBL) is a multi-functional protein that is isolated from oocytes of Rana catesbeiana. It has both lectin and ribonuclease (enzyme)…”
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    Alteration of Gene Expression Induced by Silurus asotus Lectin in Burkitt's Lymphoma Cells by Kawano, Tasuku, Sugawara, Shigeki, Hosono, Masahiro, Tatsuta, Takeo, Nitta, Kazuo

    Published in Biological & Pharmaceutical Bulletin (01-05-2008)
    “…Silurus asotus lectin (SAL) is a member of the rhamnose-binding lectin (RBL) family, and recognizes globotriaosylceramide (Gb3) on the cell surface of…”
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