Search Results - "Sugarbaker, E V"

Apoptosis in breast carcinomas detected with monoclonal antibody to single-stranded DNA: relation to bcl-2 expression, hormone receptors, and lymph node metastases by FRANKFURT, O. S, ROBB, J. A, SUGARBAKER, E. V, VILLA, L

“…Precise quantitation of apoptotic cells in solid tumors is necessary to determine the role of apoptosis in cancer growth, prognosis, and treatment. In this…”
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Synergistic induction of apoptosis in breast cancer cells by tamoxifen and calmodulin inhibitors by Frankfurt, Oskar S., Sugarbaker, Everett V., Robb, James A., Villa, Luis

“…Breast cancer cells are relatively resistant to the induction of apoptosis (AP) and drug regimens which readily activate apoptotic death, may enhance the…”
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Inhibition of DNA repair in cells treated with a combination of alkylating agents by Frankfurt, O S, Seckinger, D, Sugarbaker, E V

“…Aphidicolin (AP) or hydroxyurea (HU) inhibited DNA repair and enhanced cytotoxicity in human ovarian carcinoma cells A2780 treated with L-phenylalanine mustard…”
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Monoclonal Antibody to Single-Stranded DNA Is a Specific and Sensitive Cellular Marker of Apoptosis by Frankfurt, Oskar S., Robb, James A., Sugarbaker, Everett V., Villa, Luis

“…The most widely used histochemical marker of apoptosis (in situend labeling, TUNEL) detects both apoptotic and necrotic cells and evaluates only late stages of…”
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Prognostic indicators including DNA histogram type, receptor content, and staging related to human breast cancer patient survival by COULSON, P. B, THORNTHWAITE, J. T, WOOLLEY, T. W, SUGARBAKER, E. V, SECKINGER, D

“…Primary tumors from breast cancer patients were evaluated for the biochemical presence of three steroid cytosolic receptors and by DNA histogram analysis using…”
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Apoptosis in human breast and gastrointestinal carcinomas. Detection in histological sections with monoclonal antibody to single-stranded DNA by Frankfurt, O S, Robb, J A, Sugarbaker, E V, Villa, L

“…We report application of a novel immunohistochemical procedure for the staining of apoptotic (AP) cells in paraffin sections using monoclonal antibody (MAb) to…”
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Intercellular transfer of drug resistance by FRANKFURT, O. S, SECKINGER, D, SUGARBAKER, E. V

“…The effect of L-phenylalanine mustard (L-PAM) on heterogeneous cell populations containing sensitive and resistant cells was evaluated by flow cytometric…”
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Apoptosis (programmed cell death) and the evaluation of chemosensitivity in chronic lymphocytic leukemia and lymphoma by Frankfurt, O S, Byrnes, J J, Seckinger, D, Sugarbaker, E V

“…Chronic lymphocytic leukemia and lymphoma cells were treated with antitumor drugs in vitro and analyzed by flow cytometry to measure the number of apoptotic…”
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Flow cytometric analysis of DNA damage and repair in the cells resistant to alkylating agents by FRANKFURT, O. S, SECHKINGER, D, SUGARBAKER, E. V

“…DNA damage in the cells sensitive and resistant to alkylating agents was determined by flow cytometry analysis of cells stained with anti-DNA monoclonal…”
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Some characteristics of metastasis in man by Sugarbaker, EV

“…The studies of experimental cancer metastasis are only truly meaningful to the degree that knowledge applicable to the therapeutic problem of cancer metastasis…”
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Mechanisms and prevention of cancer dissemination: an overview by Sugarbaker, E V, Ketcham, A S

“…Synthesizing data from many experimental and clinical courses, a current working model for tumor dissemination has been constructed. Several aspects of this…”
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Melanoma of the trunk: the results of surgical excision and anatomic guidelines for predicting nodal metastasis by Sugarbaker, E V, McBride, C M

“…From 1958 through 1969, inclusive, 418 patients with melanoma of the trunk were treated at the M. D. Anderson Hospital and Tumor Institute. Of these, 128…”
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Dual immunofluorescent analysis of human peripheral blood lymphocytes by Thornthwaite, J T, Seckinger, D, Sugarbaker, E V, Rosenthal, P K, Vazquez, D A

“…These studies reveal that a dual immunofluorescent labeling method is useful for enumerating cells from human peripheral blood that bear the helper,…”
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Prophylactic isolation-perfusion as the primary therapy for invasive malignant melanoma of the limbs by McBride, C M, Sugarbaker, E V, Hickey, R C

“…The most common causes of treatment failure in patients with malignant melanoma treated by surgical therapy alone are local or regional recurrences. These are…”
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Pleiotropic drug resistance and survival advantage in leukemic cells with diminished apoptotic response by Frankfurt, O S, Seckinger, D, Sugarbaker, E V

“…Cell line R9 generated by continuous exposure of MOLT-4 cells to adriamycin was cross-resistant to a variety of unrelated drugs. The following data indicate…”
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DNA flow cytometry of pleural effusions. Comparison with pathology for the diagnosis of malignancy by Evans, D A, Thornthwaite, J T, Ng, A B, Sugarbaker, E V

“…A study was undertaken to determine the potential value of DNA flow cytometry (FCM) for the diagnosis of malignancy in pleural effusions and to compare its…”
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The complex clinical model of metastasis by Sugarbaker, E V

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The effects of syngeneic soluble tumor membrane extract on concomitant spleen cell immunity and spontaneous metastases by Temple, W J, Sugarbaker, E V, Ketcham, A S

“…The effects of a soluble tumor KCl extract, containing membrane antigen on spontaneous metastases and spleen cell immunity were studied in a syngeneic C57BL/6J…”
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Do metastases metastasize? by Sugarbaker, E V, Cohen, A M, Ketcham, A S

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Cancer metastasis: a product of tumor-host interactions by Sugarbaker, E V

“…Metastasis continues to be the most devastating event for the patient with an established primary cancer. The most significant therapeutic problems are: (1)…”
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