Search Results - "Sugama, S."

Stress induced morphological microglial activation in the rodent brain: Involvement of interleukin-18 by Sugama, S, Fujita, M, Hashimoto, M, Conti, B

“…Abstract The present study investigated the possibility that acute stress might activate microglial cells. Wistar rats were exposed to 2 h period of restraint…”
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Corticosteroids limit microglial activation occurring during acute stress by Sugama, S, Takenouchi, T, Fujita, M, Kitani, H, Conti, B, Hashimoto, M

“…Highlights ► The present study investigated the effects of corticosteroids on microglia in the rat brain following acute stress. ► Acute stress induced…”
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Immunological responses of astroglia in the rat brain under acute stress: interleukin 1 beta co-localized in astroglia by Sugama, S, Takenouchi, T, Sekiyama, K, Kitani, H, Hashimoto, M

“…Abstract In previous studies, we demonstrated that acute stress induces microglial activation, without inducing any inflammatory responses; however, the effect…”
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Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment by Sugama, S., Wirz, S.A., Barr, A.M., Conti, B., Bartfai, T., Shibasaki, T.

“…Recent reports have revealed an involvement of microglial cells in dopaminergic neurodegeneration. In the present study, we tested the hypothesis that…”
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Interleukin-18 mRNA expression in the rat pituitary gland by Wang, N., Sugama, S., Conti, B., Teramoto, A., Shibasaki, T.

“…The present study investigated the expression of IL-18 mRNA under several stimuli, and molecular structures of IL-18 mRNA of the rat pituitary. Real-time PCR…”
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Temporal and sequential analysis of microglia in the substantia nigra following medial forebrain bundle axotomy in rat by Sugama, S, Cho, B.P, Degiorgio, L.A, Shimizu, Y, Kim, S.S, Kim, Y.S, Shin, D.H, Volpe, B.T, Reis, D.J, Cho, S, Joh, T.H

“…Dopaminergic neurons in the substantia nigra pars compacta undergo apoptosis after transection of the medial forebrain bundle. We have assessed the temporal…”
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Cell-type specific signal transduction and gene regulation via mitogen-activated protein kinase pathway in catecholaminergic neurons by restraint stress by Shimizu, Y., Sugama, S., Degiorgio, L.A., Cho, B.P., Joh, T.H.

“…It has been demonstrated that tyrosine hydroxylase (TH) gene is easily regulated in the CNS as well as peripheral nervous systems by stressful conditions. The…”
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Antibiotics during Pregnancy is a Risk Factor for Child's Eczema and Wheezing by Ohya, Y, Nomura, I, Natori, M, Kitagawa, M, Akasawa, A, Sugama, S, Aizawa, S, Takayama, J.I

“…The factors that significantly influenced on the occurrence of infantile eczema were usage of antibiotics for mother who admitted to the hospital before…”
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Psychiatric inpatients and chromosome deletions within 22q11.2 by Sugama, Seiichi, Namihira, Tomoo, Matsuoka, Rumiko, Taira, Naoki, Eto, Yoshikatsu, Maekawa, Kihei

“…Velocardiofacial syndrome (VCFS) is a congenital disorder characterised by multiple dysmorphisms, cleft palate, cardiac anomalies, and learning disabilities…”
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Frontal lobe dementia with abnormal cholesterol metabolism and heterozygous mutation in sterol 27‐hydroxylase gene (CYP27) by Sugama, S., Kimura, A., Chen, W., Kubota, S., Seyama, Y., Taira, N., Eto, Y.

“…Of the primary dementing disorders that cause frontotemporal dementia, the best‐known is Pick disease. We report on a 44‐year‐old woman with progressive…”
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Tissue-Specific Expression of Rat IL-18 Gene and Response to Adrenocorticotropic Hormone Treatment by Sugama, Shuei, Kim, Yoonseong, Baker, Harriet, Tinti, Cristina, Kim, Hocheol, Joh, Tong H, Conti, Bruno

“…IL-18 is a pleiotropic cytokine also proposed to have a role in modulating immune function during stress. Initially found in immune cells, IL-18 mRNA is…”
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Morphometry of the head of the caudate nucleus in patients with velocardiofacial syndrome (del 22qll.2) by Sugama, S, Bingham, PM, Wang, PP, Moss, EM, Kobayashi, H, Eto, Y

“…Velocardiofacial syndrome (VCFS) is a chromosomal anomaly syndrome characterized by multiple congenital malformations, including cleft palate and cardiac…”
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Monozygous twin with polymicrogyria and normal co-twin by Sugama, S, Kusano, K

“…Monozygous twinning has been associated with brain lesions such as holoprosencephaly, hydranencephaly, multicystic encephalomalacia, and porencephaly…”
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Morphometry of the head of the caudate nucleus in patients with velocardiofacial syndrome (del 22q11.2) by Sugama, S, Bingham, P M, Wang, P P, Moss, E M, Kobayashi, H, Eto, Y

“…Velocardiofacial syndrome (VCFS) is a chromosomal anomaly syndrome characterized by multiple congenital malformations, including cleft palate and cardiac…”
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P4780Activation of astrocytes is requred for the persistence of post-stress blood pressure elevation by Hasebe, Y, Yokota, S, Takeda, K, Sugama, S, Kono, Y, Koizumi, K, Fukushi, I, Hoshiai, M, Kakinuma, Y, Pokorski, M, Horiuchi, J, Sugita, K, Okada, Y

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Expression of α-synuclein, a presynaptic protein implicated in Parkinson’s disease, in erythropoietic lineage by Nakai, Masaaki, Fujita, Masayo, Waragai, Masaaki, Sugama, Shuei, Wei, Jianshe, Akatsu, Hiroyasu, Ohtaka-Maruyama, Chiaki, Okado, Haruo, Hashimoto, Makoto

“…The present study investigated expression of α-synuclein (α-syn), a presynaptic protein involved in the pathogenesis of Parkinson’s disease, in erythroid…”
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Interleukin-18 and stress by Sugama, Shuei, Conti, Bruno

“…Abstract Interleukin-18 (IL-18) is a pro-inflammatory cytokine believed to play a role in a variety of conditions and diseases including infections,…”
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Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis In vivo by Solforosi, Laura, Criado, Jose R., McGavern, Dorian B., Wirz, Sebastian, Sánchez-Alavez, Manuel, Sugama, Shuei, DeGiorgio, Lorraine A., Volpe, Bruce T., Wiseman, Erika, Abalos, Gil, Masliah, Eliezer, Gilden, Donald, Oldstone, Michael B., Conti, Bruno, Williamson, R. Anthony

“…Neuronal death is a prominent, but poorly understood, pathological hallmark of prion disease. Notably, in the absence of the cellular prion protein PrPC), the…”
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pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation by Kim, Yoon Seong, Choi, Dong Hee, Block, Michelle L, Lorenzl, Stefan, Yang, Lichuan, Kim, Youn Jung, Sugama, Shuei, Cho, Byung Pil, Hwang, Onyou, Browne, Susan E, Kim, Soo Yul, Hong, Jau-Shyong, Beal, M. Flint, Joh, Tong H

“…Recent studies have demonstrated that activated microglia play an important role in dopamine (DA) neuronal degeneration in Parkinson disease (PD) by generating…”
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Differential microglial activation between acute stress and lipopolysaccharide treatment by Sugama, Shuei, Takenouchi, Takato, Fujita, Masayo, Conti, Bruno, Hashimoto, Makoto

“…Abstract Acute stress was demonstrated to induce morphological microglial activation in several brain regions including the midbrain periaqueductal gray (PAG),…”
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