Search Results - "Suffness, Matthew"

The Taxol Supply Crisis. New NCI Policies for Handling the Large-Scale Production of Novel Natural Product Anticancer and Anti-HIV Agents by Cragg, Gordon M, Schepartz, Saul A, Suffness, Matthew, Grever, Michael R

“…Over the past 30 years, the National Cancer Institute has been involved in the preclinical and/or clinical evaluation of the majority of those agents approved…”
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Antitumor Agents. 163. † Three-Dimensional Quantitative Structure−Activity Relationship Study of 4‘-O-Demethylepipodophyllotoxin Analogs Using the Modified CoMFA/q2-GRS Approach by Cho, Sung Jin, Tropsha, Alexander, Suffness, Matthew, Cheng, Yung-Chi, Lee, Kuo-Hsiung

“…Analogs of 4‘-O-demethylepipodophyllotoxin are considered as potential anticancer agents. We have applied comparative molecular field analysis (CoMFA) and a…”
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Occurrence of Sesbanimide in Seeds of Toxic Sesbania Species by Powell, Richard G., Plattner, Ronald D., Suffness, Matthew

“…A tandem mass spectrometric procedure was developed to detect sesbanimide A and its isomers in plant materials. Analysis of seed extracts from 10 Sesbania…”
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Antineoplastic agents. 104. Isolation and structure of the Phyllanthus acuminatus Vahl (Euphorbiaceae) glycosides by Pettit, George R, Cragg, Gordon M, Suffness, Matthew I, Gust, Devens, Boettner, Fred E, Williams, M, Saenz-Renauld, J. A, Brown, Peter, Schmidt, Jean M, Ellis, Paul D

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Mosses, liverworts, and hornworts screened for antitumor agents by Spjut, R.W, Suffness, M, Cragg, G.M, Norris, D.H

“…The National Cancer Institute's record of bryophytes (mosses, liverworts, and hornworts) screened for biologically active chemicals is reviewed. In 1977, an…”
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Echinomycin: the first bifunctional intercalating agent in clinical trials by Foster, B J, Clagett-Carr, K, Shoemaker, D D, Suffness, M, Plowman, J, Trissel, L A, Grieshaber, C K, Leyland-Jones, B

“…Echinomycin is a quinoxaline antibiotic that was originally isolated from Streptomyces echinatus. Based on its antitumor activity against two i.p. implanted…”
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Variation in cytotoxicity and antitumor activity among samples of the mossClaopodium crispifolium (Thuidiaceae) by Spjut, Richard W., Edson, Charles F., Cassady, John M., McCloud, Tom, Suffness, Matthew, Norris, Daniel H., Cragg, Gordon M.

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Variation in cytotoxicity and antitumor activity among samples of the moss Claopodium crispifolium (Thuidiaceae) by Richard W. Spjut, Cassady, John M., Tom Mc Cloud, Matthew Suffness, Norris, Daniel H., Cragg, Gordon M., Charles F. Edson

“…Nine samples of the moss Claopodium crispifolium were collected for large-scale fractionation to isolate antitumor agents. Each sample was active in the P388…”
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Isolation and structure elucidation of oxoxylopine, a new oxoaporphine alkaloid from Stephania abyssinica by Kupchan, S. Morris, Suffness, Matthew I, Gordon, Eric M

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Biogenetic-type synthesis of the isoeuphenol system by Van Tamelen, Eugene E, Milne, G. M, Suffness, Matthew I, Chauvin, M. C. Rudler, Anderson, Richard James, Achini, R. S

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Isolation and structural elucidation of 4-demethylhasubanonine, a new alkaloid from Stephania hernandifolia by Kupchan, S. Morris, Suffness, Matthew I, White, D. N. J, McPhail, Andrew T, Sim, G. A

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Structure of stephavanine, a novel Hasubanan ester alkaloid by Kupchan, S. Morris, Suffness, Matthew I, McClure, Richard J, Sim, George A

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Current Status of the NCI Plant and Animal Product Program by Suffness, Matthew, Douros, John

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Metabolism of plant-derived anticancer agents by Cragg, G, Suffness, M

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New antitumor substances of natural origin by Douros, J, Suffness, M

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Colchicine and its analogues: recent findings by Brossi, A, Yeh, H J, Chrzanowska, M, Wolff, J, Hamel, E, Lin, C M, Quin, F, Suffness, M, Silverton, J

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Antitumor activity and biochemical effects of aphidicolin glycinate (NSC 303812) alone and in combination with cisplatin in vivo by O'DWYER, P. J, MOYER, J. D, SUFFNESS, M, HARRISON, S. D, CYSYK, R, HAMILTON, T. C, PLOWMAN, J

“…Aphidicolin, an inhibitor of DNA polymerases alpha and delta, is cytotoxic in vitro against tumor cells. The poor solubility of aphidicolin has led to the…”
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Antitumor Agents. 163. Three-Dimensional Quantitative Structure−Activity Relationship Study of 4‘- O -Demethylepipodophyllotoxin Analogs Using the Modified CoMFA/q 2 -GRS Approach by Cho, Sung Jin, Tropsha, Alexander, Suffness, Matthew, Cheng, Yung-Chi, Lee, Kuo-Hsiung

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Phyllanthostatin 1-phyllanthoside orthoacid rearrangement by PETIT, G. R, CRAGG, G. M, SUFFNESS, M

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Didemnin B. The first marine compound entering clinical trials as an antineoplastic agent by Chun, H G, Davies, B, Hoth, D, Suffness, M, Plowman, J, Flora, K, Grieshaber, C, Leyland-Jones, B

“…A new class of marine compounds, the didemnins, with potent antitumor activity has been identified. They share the novel structure of a cyclic depsipeptide…”
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