Search Results - "Sudoh, Shinji"
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Subclinical elevation of plasma C-reactive protein and illusions/hallucinations in subjects with Parkinson's disease: case-control study
Published in PloS one (31-01-2014)“…Though infections are associated with psychotic symptoms, whether or not subclinical inflammation is associated with hallucinations is not known in Parkinson's…”
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Definite familial multiple system atrophy with unknown genetics
Published in Neuropathology (01-06-2014)“…Multiple system atrophy (MSA) is an oligodendrogliopathy of presumably sporadic origin, characterized by prominent α‐synuclein inclusions with neuronal…”
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Stroke-Independent Association Between Metabolic Syndrome and Functional Dependence, Depression, and Low Quality of Life in Elderly Community-Dwelling Brazilian People
Published in Journal of the American Geriatrics Society (JAGS) (01-03-2007)“…OBJECTIVES: Metabolic syndrome (Met.S) is a risk factor for stroke, dementia, and ischemic heart disease (IHD). It is unclear whether Met.S is an independent…”
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Safety and tolerability of immune globulin intravenous (human), 10% solution in Japanese subjects with mild to moderate Alzheimer's disease
Published in Psychogeriatrics (01-09-2014)“…Background Immune globulin intravenous (IGIV), 10% is a donor‐derived polyclonal human immunoglobulin G antibody mixture that has potent immune modulatory…”
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Incidence of dementia, Alzheimer disease, and vascular dementia in a Japanese population: Radiation Effects Research Foundation adult health study
Published in Neuroepidemiology (01-01-2008)“…To determine the age-, sex-, and subtype-specific incidence of dementia and to assess the effect of education level on the incidence in a Japanese population…”
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Prevalence and Risks of Dementia in the Japanese Population: RERF's Adult Health Study Hiroshima Subjects
Published in Journal of the American Geriatrics Society (JAGS) (01-02-1999)“…OBJECTIVES: To study the prevalence rate of dementia and its subtypes in Japan and to investigate the relationship of risk factors, such as demographic…”
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Efficacy and Safety of Cilostazol in Mild Cognitive Impairment: A Randomized Clinical Trial
Published in JAMA network open (01-12-2023)“…Recent evidence indicates the efficacy of β-amyloid immunotherapy for the treatment of Alzheimer disease, highlighting the need to promote β-amyloid removal…”
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Cognitive impairment and frontal-subcortical geriatric syndrome are associated with metabolic syndrome in a stroke-free population
Published in Neurobiology of aging (01-11-2007)“…Abstract Background Metabolic syndrome (Met.S) consists of a conglomeration of obesity, hypertension, glucose intolerance, and dislipidemia…”
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Differential Effects of Proteases Involved in Intracellular Degradation of Amyloid β-Protein between Detergent-Soluble and -Insoluble Pools in CHO-695 Cells
Published in Biochemistry (Easton) (29-01-2002)“…The deposition of amyloid β-protein (Aβ or βA4) is a key feature of Alzheimer's disease. Most studies have focused on the generation of Aβ, but little is known…”
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Safety and tolerability of immune globulin intravenous (human), 10% solution in J apanese subjects with mild to moderate A lzheimer's disease
Published in Psychogeriatrics (01-09-2014)“…Abstract Background Immune globulin intravenous ( IGIV ), 10% is a donor‐derived polyclonal human immunoglobulin G antibody mixture that has potent immune…”
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Neurologic and histopathologic evaluation after high-volume intrathecal amitriptyline
Published in Regional anesthesia and pain medicine (01-09-2004)“…Accumulating evidence indicates that amitriptyline decreases pain sensation when administered orally, intraperitoneally, or for sciatic nerve block. Previous…”
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A case of optic-spinal form of multiple sclerosis with lobar type large cerebral hemorrhage
Published in Rinshō shinkeigaku (01-07-1997)“…We report a 57-year-old woman with optic-spinal form of active multiple sclerosis, who developed a large lobar type hemorrhage of the brain. She initially…”
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Presenilin 1 Mutations Linked to Familial Alzheimer's Disease Increase the Intracellular Levels of Amyloid β‐Protein 1–42 and Its N‐Terminally Truncated Variant(s) Which Are Generated at Distinct Sites
Published in Journal of neurochemistry (01-10-1998)“…: Mutations in the presenilin genes PS1 and PS2 cause the most common form of early‐onset familial Alzheimer's disease. The influence of PS1 mutations on the…”
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Neurologic and histopathologic evaluation after high-volume intrathecal amitriptyline
Published in Regional anesthesia and pain medicine (01-09-2004)Get full text
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Intracellular site of γ‐secretase cleavage for Aβ42 generation in Neuro 2a cells harbouring a presenilin 1 mutation
Published in European journal of biochemistry (01-04-2000)“…Previously, we reported that mutations in presenilin 1 (PS1) increased the intracellular levels of amyloid β‐protein (Aβ)42. However, it is still not known at…”
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Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of β‐catenin phosphorylation
Published in European journal of biochemistry (01-05-2001)“…Mutations in the presenilin 1 (PS1) gene are the most common genetic factor underlying the development of early onset familial Alzheimer's disease (FAD)…”
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Implications of presenilin 1 mutations in Alzheimer’s disease
Published in Mechanisms of ageing and development (15-03-1999)“…Mutations in presenilin 1 ( PS1) and presenilin 2 ( PS2) are the most common genetic factors underlying the development of early-onset familial Alzheimer’s…”
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Ciliary neurotrophic factor induced-increase in beta-amyloid precursor protein mRNA in rat C6 glioma cells
Published in Biochemical and biophysical research communications (15-10-1994)“…The effect of ciliary neurotrophic factor (CNTF) on beta-amyloid precursor protein (APP) gene expression was investigated in cultured rat C6 glioma cells and…”
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Definite familial multiple system atrophy with unknown genetics
Published in Neuropathology (01-06-2014)Get full text
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Serum deprivation alters the expression and the splicing at exons 7, 8 and 15 of the β-amyloid precursor protein in the C6 glioma cell line
Published in Brain research. Molecular brain research. (01-07-1996)“…Amyloid deposition characterizes the pathological lesions of Alzheimer's disease. We investigated the effect of serum deprivation on the regulation of…”
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