Search Results - "Sudhakaran, Meenakshi"
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The Targeted Impact of Flavones on Obesity-Induced Inflammation and the Potential Synergistic Role in Cancer and the Gut Microbiota
Published in Molecules (Basel, Switzerland) (27-05-2020)“…Obesity is an inflammatory disease that is approaching pandemic levels, affecting nearly 30% of the world's total population. Obesity increases the risk of…”
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Role of Heterogeneous Nuclear Ribonucleoproteins in the Cancer-Immune Landscape
Published in International journal of molecular sciences (01-03-2023)“…Cancer remains the second leading cause of death, accounting for approximately 20% of all fatalities. Evolving cancer cells and a dysregulated immune system…”
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Flavonoids: New Frontier for Immuno-Regulation and Breast Cancer Control
Published in Antioxidants (16-04-2019)“…Breast cancer (BC) remains the second most common cause of cancer-related deaths in women in the US, despite advances in detection and treatment. In addition,…”
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Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple-negative breast cancer
Published in Cell death & disease (13-12-2023)“…Triple-negative breast cancer (TNBC) is characterized by its aggressiveness and resistance to cancer-specific transcriptome alterations. Alternative splicing…”
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Tart Cherry (Prunus cerasus L.) Pit Extracts Protect Human Skin Cells against Oxidative Stress: Unlocking Sustainable Uses for Food Industry Byproducts
Published in Foods (01-10-2023)“…Industrial processing of tart cherries (Prunus cerasus L.) produces bioproducts like cherry pits (CP), which contribute to adverse environmental effects. To…”
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Apigenin by targeting hnRNPA2 sensitizes triple-negative breast cancer spheroids to doxorubicin-induced apoptosis and regulates expression of ABCC4 and ABCG2 drug efflux transporters
Published in Biochemical pharmacology (01-12-2020)“…[Display omitted] Acquired resistance to doxorubicin is a major hurdle in triple-negative breast cancer (TNBC) therapy, emphasizing the need to identify…”
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Abstract B035: Reciprocal macrophage - T cell interactions regulate anti-tumor immunity
Published in Cancer research (Chicago, Ill.) (17-11-2024)“…Cancer immunotherapy (including immune checkpoint blockade (ICB)) has shown great promise in the treatment of some solid cancers, but responses in breast…”
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Arachidin-1, a Prenylated Stilbenoid from Peanut, Enhances the Anticancer Effects of Paclitaxel in Triple-Negative Breast Cancer Cells
Published in Cancers (07-01-2023)“…Triple-negative breast cancer (TNBC) is one of the deadliest forms of breast cancer. Investigating alternative therapies to increase survival rates for this…”
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Dietary Flavonoids Targeting Triple Negative Breast Cancer
Published in Current developments in nutrition (01-06-2020)“…Breast cancer remains the leading cause of malignancy-related death in females and continues to increase in prevalence worldwide. The lack of therapies for…”
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