Search Results - "Sudhakar, Cherukuri"

NF-κB Mediates Tumor Necrosis Factor α-Induced Expression of Optineurin, a Negative Regulator of NF-κB by Sudhakar, Cherukuri, Nagabhushana, Ananthamurthy, Jain, Nishant, Swarup, Ghanshyam

“…Optineurin is a ubiquitously expressed multifunctional cytoplasmic protein encoded by OPTN gene. The expression of optineurin is induced by various cytokines…”
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Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein by Bansal, Megha, Moharir, Shivranjani C., Sailasree, S. Purnima, Sirohi, Kapil, Sudhakar, Cherukuri, Sarathi, D. Partha, Lakshmi, B. Jyothi, Buono, Mario, Kumar, Satish, Swarup, Ghanshyam

“…Autophagy is a quality-control mechanism that helps to maintain cellular homeostasis by removing damaged proteins and organelles through lysosomal degradation…”
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Optineurin mediates negative regulation of Rab8 function by TBC1D17, a GTPase activating protein by Vaibhava, Vipul, Nagabhushana, Ananthamurthy, Chalasani, Madhavi Latha Somaraju, Sudhakar, Cherukuri, Kumari, Asha, Swarup, Ghanshyam

“…Rab GTPases regulate various membrane trafficking pathways but the mechanisms by which GTPase activating proteins recognize specific Rabs are not clear. Rab8…”
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NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB by Sudhakar, Cherukuri, Nagabhushana, Ananthamurthy, Jain, Nishant, Swarup, Ghanshyam

“…Optineurin is a ubiquitously expressed multifunctional cytoplasmic protein encoded by OPTN gene. The expression of optineurin is induced by various cytokines…”
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M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells by Sirohi, Kapil, Chalasani, Madhavi Latha Somaraju, Sudhakar, Cherukuri, Kumari, Asha, Radha, Vegesna, Swarup, Ghanshyam

“…Mutations in the autophagy receptor OPTN/optineurin are associated with the pathogenesis of glaucoma and amyotrophic lateral sclerosis, but the underlying…”
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Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17 by Vaibhava, Vipul, Nagabhushana, Ananthamurthy, Chalasani, Madhavi Latha Somaraju, Sudhakar, Cherukuri, Kumari, Asha, Swarup, Ghanshyam

“…Rab GTPases regulate various membrane trafficking pathways but the mechanisms by which GTPase-activating proteins recognise specific Rabs are not clear. Rab8…”
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IRF-1-binding site in the first intron mediates interferon-γ-induced optineurin promoter activation by Sudhakar, Cherukuri, Vaibhava, Vipul, Swarup, Ghanshyam

“…•IRF-1 is a strong activator of optineurin promoter.•IRF-1-binding site is present in the first intron of optineurin gene.•Interferon-γ-induced optineurin…”
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Sp1-like sequences mediate human caspase-3 promoter activation by p73 and cisplatin by Sudhakar, Cherukuri, Jain, Nishant, Swarup, Ghanshyam

“…Caspase-3 is a cysteine protease that plays a central role in the execution of apoptosis induced by a wide variety of stimuli. However, little is known about…”
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NF-[kappa]B Mediates Tumor Necrosis Factor [alpha]-Induced Expression of Optineurin, a Negative Regulator of NF-[kappa]B by Sudhakar, Cherukuri, Nagabhushana, Ananthamurthy, Jain, Nishant, Swarup, Ghanshyam

“…Optineurin is a ubiquitously expressed multifunctional cytoplasmic protein encoded by OPTN gene. The expression of optineurin is induced by various cytokines…”
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Significance of glycosylation patterns of rat Zajdela ascitic hepatocellular carcinoma: Effect of enzymatic removal of surface sialic acid on humoral response by Sudhakar, Cherukuri, Mangamoori, Lakshmi N

“…Background and Aim:  Rat Zajdela ascitic hepatocellular carcinoma (ZAH) is a malignant cell type with some properties in common with rat hepatocytes. The aim…”
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