Search Results - "Sudha, Parvathi"

Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth by Guo, Minzhe, Du, Yina, Gokey, Jason J., Ray, Samriddha, Bell, Sheila M., Adam, Mike, Sudha, Parvathi, Perl, Anne Karina, Deshmukh, Hitesh, Potter, S. Steven, Whitsett, Jeffrey A., Xu, Yan

“…The respiratory system undergoes a diversity of structural, biochemical, and functional changes necessary for adaptation to air breathing at birth. To identify…”
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1q amplification and PHF19 expressing high-risk cells are associated with relapsed/refractory multiple myeloma by Johnson, Travis S., Sudha, Parvathi, Liu, Enze, Becker, Nathan, Robertson, Sylvia, Blaney, Patrick, Morgan, Gareth, Chopra, Vivek S., Dos Santos, Cedric, Nixon, Michael, Huang, Kun, Suvannasankha, Attaya, Zaid, Mohammad Abu, Abonour, Rafat, Walker, Brian A.

“…Multiple Myeloma is an incurable plasma cell malignancy with a poor survival rate that is usually treated with immunomodulatory drugs (iMiDs) and proteosome…”
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FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma by Milewski, David, Shukla, Samriddhi, Gryder, Berkley E., Pradhan, Arun, Donovan, Johnny, Sudha, Parvathi, Vallabh, Sushmitha, Pyros, Athena, Xu, Yan, Barski, Artem, Szabo, Sara, Turpin, Brian, Pressey, Joseph G., Millay, Douglas P., Khan, Javed, Kalinichenko, Vladimir V., Kalin, Tanya V.

“…The PAX3-FOXO1 fusion protein is the key oncogenic driver in fusion positive rhabdomyosarcoma (FP-RMS), an aggressive soft tissue malignancy with a…”
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Alternative splicing in multiple myeloma is associated with the non-homologous end joining pathway by Liu, Enze, Becker, Nathan, Sudha, Parvathi, Dong, Chuanpeng, Liu, Yunlong, Keats, Jonathan, Morgan, Gareth, Walker, Brian A.

“…Alternative splicing plays a pivotal role in tumorigenesis and proliferation. However, its pattern and pathogenic role has not been systematically analyzed in…”
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Identifying novel mechanisms of biallelic TP53 loss refines poor outcome for patients with multiple myeloma by Liu, Enze, Sudha, Parvathi, Becker, Nathan, Jaouadi, Oumaima, Suvannasankha, Attaya, Lee, Kelvin, Abonour, Rafat, Abu Zaid, Mohammad, Walker, Brian A.

“…Biallelic TP53 inactivation is the most important high-risk factor associated with poor survival in multiple myeloma. Classical biallelic TP53 inactivation has…”
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YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1 by Gokey, Jason J., Snowball, John, Sridharan, Anusha, Sudha, Parvathi, Kitzmiller, Joseph A., Xu, Yan, Whitsett, Jeffrey A.

“…Ventilation is dependent upon pulmonary alveoli lined by two major epithelial cell types, alveolar type-1 (AT1) and 2 (AT2) cells. AT1 cells mediate gas…”
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Abstract 450: A targeted capture panel to identify translocations, copy number abnormalities, and mutations in multiple myeloma by Walker, Brian Andrew, Ahsan, Aarif, Sudha, Parvathi, Kausar, Tasneem, Rane, Sushmita, Flynt, Erin, Thakurta, Anjan

“…Abstract Multiple myeloma (MM) is a genetically heterogeneous disease where risk stratification and outcomes are associated with translocations of the…”
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The Frequency of Alternative Splicing in Multiple Myeloma Is Determined By the Non-Homologous End Joining Pathway by Liu, Enze, Becker, Nathan, Sudha, Parvathi, Dong, Chuanpeng, Liu, Yunlong, Keats, Jonathan J, Morgan, Gareth J., Walker, Brian A.

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Unraveling Diverse Mechanisms of Complex Structural Variant Interactions through Multiomic Data in Multiple Myeloma by Liu, Enze, Becker, Nathan, Sudha, Parvathi, Mikulasova, Aneta, Abu Zaid, Mohammad, Suvannasankha, Attaya, Lee, Kelvin P., Abonour, Rafat, Walker, Brian A.

“…Introduction: Structural variants (SVs) play a role in proliferation of plasma cells that characterizes multiple myeloma (MM). Several hallmark SVs have been…”
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Single-Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell by Guo, Minzhe, Yu, Jane J, Perl, Anne Karina, Wikenheiser-Brokamp, Kathryn A, Riccetti, Matt, Zhang, Erik Y, Sudha, Parvathi, Adam, Mike, Potter, Andrew, Kopras, Elizabeth J, Giannikou, Krinio, Potter, S Steven, Sherman, Sue, Hammes, Stephen R, Kwiatkowski, David J, Whitsett, Jeffrey A, McCormack, Francis X, Xu, Yan

“…Lymphangioleiomyomatosis (LAM) is a metastatic neoplasm of reproductive-age women associated with mutations in tuberous sclerosis complex genes. LAM causes…”
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Patient Derived Xenografts Highlight Mouse-Specific Tumor Evolution Patterns and Genomic Diversity of Multiple Myeloma by Becker, Nathan, Liu, Enze, Sudha, Parvathi, Mikulasova, Aneta, Johnson, Travis S, Suvannasankha, Attaya, Abu Zaid, Mohammad Issam, Abonour, Rafat, Walker, Brian A.

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Single Cell Multiomic Analysis Reveals Relapsed and Refractory Multiple Myeloma Cells Associated with 1q, TP53, and PHF19 alterations That Affect Subclonal Chromatin Accessibility by Johnson, Travis S, Sudha, Parvathi, Liu, Enze, Chopra, Vivek S., Dos Santos, Cedric E., Nixon, Michael, Huang, Kun, Abonour, Rafat, Abu Zaid, Mohammad Issam, Walker, Brian A.

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Prospective Molecular Characterization of Multiple Myeloma Patient Samples Identifies High-Risk Patients and Informs Treatment Sequences through Resistance Mechanisms to Immunotherapies by Pham, Phillip, Sudha, Parvathi, Wang, Lin, Niu, Wen, Morgan, Cameron, Ligocki, Cameron, Al-Azzawi, Ramzi, Ly, Reynold, Vetrini, Francesco, Czader, Magdalena, Tayeh, Marwan, Abu Zaid, Mohammad, Lee, Kelvin P., Suvannasankha, Attaya, Abonour, Rafat, Walker, Brian A.

“…Introduction. Multiple myeloma (MM) genetic diagnostics has traditionally been performed using fluorescence in situ hybridization (FISH), giving prognostic…”
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The Pre-Existing T Cell Landscape Is Associated with Response to High Dose Melphalan and Autologous Stem Cell Transplant in Multiple Myeloma by Abu Zaid, Mohammad Issam, Sudha, Parvathi, Johnson, Travis S, Chopra, Vivek S., Dos Santos, Cedric E., Nixon, Michael, Suvannasankha, Attaya, Farag, Sherif S, Lee, Kelvin P., Abonour, Rafat, Walker, Brian A.

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Glucocorticoid regulates mesenchymal cell differentiation required for perinatal lung morphogenesis and function by Bridges, James P, Sudha, Parvathi, Lipps, Dakota, Wagner, Andrew, Guo, Minzhe, Du, Yina, Brown, Kari, Filuta, Alyssa, Kitzmiller, Joseph, Stockman, Courtney, Chen, Xiaoting, Weirauch, Matthew T, Jobe, Alan H, Whitsett, Jeffrey A, Xu, Yan

“…While antenatal glucocorticoids are widely used to enhance lung function in preterm infants, cellular and molecular mechanisms by which glucocorticoid receptor…”
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OA-32 The impact of genomics to identify novel immunotherapeutic targets in multiple myeloma by Liu, Enze, Sudha, Parvathi, Zaid, Mohammad Abu, Johnson, Travis, Chopra, Vivek, Santos, Cedric Dos, Nixon, Michael, Hamidi, Habib, Suvannasankha, Attaya, Lee, Kelvin, Abonour, Rafat, Walker, Brian

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OA-27 Single cell transcriptomics reveals the impact of tumor cell interactions with the bone marrow immune microenvironment in the progression of multiple myeloma by Sudha, Parvathi, Zaid, Mohammad Abu, Johnson, Travis, Chopra, Vivek, Santos, Cedric Dos, Nixon, Michael, Zafar, Faiza, Hamidi, Habib, Suvannasankha, Attaya, Farag, Sherif, Lee, Kelvin, Abonour, Rafat, Walker, Brian

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P-345 Connecting 1q amplification and PHF19 expression in high-risk myeloma clones by Johnson, Travis, Sudha, Parvathi, Liu, Enze, Chopra, Vivek, Santos, Cedric Dos, Nixon, Michael, Huang, Kun, Abonour, Rafat, Zaid, Mohammad Abu, Walker, Brian

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Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma by Sudha, Parvathi, Ahsan, Aarif, Ashby, Cody, Kausar, Tasneem, Khera, Akhil, Kazeroun, Mohammad H, Hsu, Chih-Chao, Wang, Lin, Fitzsimons, Evelyn, Salminen, Outi, Blaney, Patrick, Czader, Magdalena, Williams, Jonathan, Abu Zaid, Mohammad I, Ansari-Pour, Naser, Yong, Kwee L, van Rhee, Frits, Pierceall, William E, Morgan, Gareth J, Flynt, Erin, Gooding, Sarah, Abonour, Rafat, Ramasamy, Karthik, Thakurta, Anjan, Walker, Brian A

“…We designed a comprehensive multiple myeloma targeted sequencing panel to identify common genomic abnormalities in a single assay and validated it against…”
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MGP Panel is a comprehensive targeted genomics panel for molecular profiling of multiple myeloma patients by Sudha, Parvathi, Ahsan, Aarif, Ashby, Cody, Kausar, Tasneem, Khera, Akhil, Kazeroun, Mohammad H., Hsu, Chih-Chao, Wang, Lin, Fitzsimons, Evelyn, Salminen, Outi, Blaney, Patrick, Czader, Magdalena, Williams, Jonathan, Abu Zaid, Mohammad I, Ansari-Pour, Naser, Yong, Kwee L., van Rhee, Frits, Pierceall, William E., Morgan, Gareth J, Flynt, Erin, Gooding, Sarah, Abonour, Rafat, Ramasamy, Karthik, Thakurta, Anjan, Walker, Brian A

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