Search Results - "Sudbeck, Barry D."

The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix by Pilcher, Brian K., Dumin, Jo Ann, Sudbeck, Barry D., Krane, Stephen M., Welgus, Howard G., Parks, William C.

“…We have shown in a variety of human wounds that collagenase-1 (MMP-1), a matrix metalloproteinase that cleaves fibrillar type I collagen, is invariably…”
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Induction and Repression of Collagenase-1 by Keratinocytes Is Controlled by Distinct Components of Different Extracellular Matrix Compartments by Sudbeck, Barry D., Pilcher, Brian K., Welgus, Howard G., Parks, William C.

“…In all forms of cutaneous wounds, collagenase-1 (matrix metalloproteinase-1 (MMP-1)) is invariably expressed by basal keratinocytes migrating over the dermal…”
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Expression of 92-kDa Type IV Collagenase mRNA by Eosinophils Associated with Basal Cell Carcinoma by Stähle-Bäckdahl, Mona, Sudbeck, Barry D, Eisen, Arthur Z, Welgus, Howard G, Parks, William C

“…Metalloproteinases are thought to be important for tumor invasion and metastasis. We used in situ hybridization with 35S-labeled cRNA probes to localize sites…”
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Collagen-stimulated induction of keratinocyte collagenase is mediated via tyrosine kinase and protein kinase C activities by Sudbeck, B D, Parks, W C, Welgus, H G, Pentland, A P

“…We have previously shown that during wound healing migrating keratinocytes, which are in contact with the dermal matrix, express interstitial collagenase,…”
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Selective loss of PMA-stimulated expression of matrix metalloproteinase 1 in HaCaT keratinocytes is correlated with the inability to induce mitogen-activated protein family kinases by Sudbeck, B D, Baumann, P, Ryan, G J, Breitkopf, K, Nischt, R, Krieg, T, Mauch, C

“…Many cell types, including fibroblasts and primary keratinocytes, increase matrix metalloproteinase 1 (MMP-1) production in response to agonists such as growth…”
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Selective loss of PMA-stimulated expression of matrix metalloproteinase 1 in HaCaT keratinocytes is correlated with the inability to induce mitogen-activated protein family kinases by SUDBECK, Barry D., BAUMANN, Petra, RYAN, Gavin J., BREITKOPF, Katja, NISCHT, Roswitha, KRIEG, Thomas, MAUCH, Cornelia

“…Many cell types, including fibroblasts and primary keratinocytes, increase matrix metalloproteinase 1 (MMP-1) production in response to agonists such as growth…”
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Modulation of intracellular calcium levels inhibits secretion of collagenase 1 by migrating keratinocytes by Sudbeck, B D, Pilcher, B K, Pentland, A P, Parks, W C

“…Calcium concentration influences keratinocyte differentiation, and, following injury, keratinocytes move through an environment of changing calcium levels…”
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Collagen-mediated induction of MMP-1 requires JNK, but not ERK activity by Sudbeck, Barry D., Ryan, Gavin J., Breitkopf, Katia, Mauch, Cornelia

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Purification and characterization of bovine interstitial collagenase and tissue inhibitor of metalloproteinases by Sudbeck, B D, Jeffrey, J J, Welgus, H G, Mecham, R P, McCourt, D, Parks, W C

“…In this report we describe the purification of bovine interstitial collagenase and provide information on its substrate specificity, kinetic parameters of…”
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