Search Results - "Sudarsky, Lewis R"

Molecular markers of early Parkinson's disease based on gene expression in blood by Scherzer, Clemens R, Eklund, Aron C, Morse, Lee J, Liao, Zhixiang, Locascio, Joseph J, Fefer, Daniel, Schwarzschild, Michael A, Schlossmacher, Michael G, Hauser, Michael A, Vance, Jeffery M, Sudarsky, Lewis R, Standaert, David G, Growdon, John H, Jensen, Roderick V, Gullans, Steven R

“…Parkinson's disease (PD) progresses relentlessly and affects five million people worldwide. Laboratory tests for PD are critically needed for developing…”
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Thalamic Volume Is Reduced in Cervical and Laryngeal Dystonias by Waugh, Jeff L, Kuster, John K, Levenstein, Jacob M, Makris, Nikos, Multhaupt-Buell, Trisha J, Sudarsky, Lewis R, Breiter, Hans C, Sharma, Nutan, Blood, Anne J

“…Dystonia, a debilitating movement disorder characterized by abnormal fixed positions and/or twisting postures, is associated with dysfunction of motor control…”
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Evidence for altered basal ganglia-brainstem connections in cervical dystonia by Blood, Anne J, Kuster, John K, Woodman, Sandra C, Kirlic, Namik, Makhlouf, Miriam L, Multhaupt-Buell, Trisha J, Makris, Nikos, Parent, Martin, Sudarsky, Lewis R, Sjalander, Greta, Breiter, Henry, Breiter, Hans C, Sharma, Nutan

“…There has been increasing interest in the interaction of the basal ganglia with the cerebellum and the brainstem in motor control and movement disorders. In…”
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White Matter Changes in Cervical Dystonia Relate to Clinical Effectiveness of Botulinum Toxin Treatment by Blood, Anne J, Kuster, John K, Waugh, Jeff L, Levenstein, Jacob M, Multhaupt-Buell, Trisha J, Sudarsky, Lewis R, Breiter, Hans C, Sharma, Nutan

“…In a previous report showing white matter microstructural hemispheric asymmetries medial to the pallidum in focal dystonias, we showed preliminary evidence…”
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REM behavior disorder and excessive daytime somnolence in Machado-Joseph disease (SCA-3) by Friedman, Joseph H., Fernandez, Hubert H., Sudarsky, Lewis R.

“…We reported previously that behavior suggestive of rapid eye movement sleep behavior disorder (RBD) was markedly increased in a small population of SCA‐3…”
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Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study by Ding, Hongliu, Dhima, Kaltra, Lockhart, Kaitlin C, Locascio, Joseph J, Hoesing, Ashley N, Duong, Karen, Trisini-Lipsanopoulos, Ana, Hayes, Michael T, Sohur, U Shivraj, Wills, Anne-Marie, Mollenhauer, Brit, Flaherty, Alice W, Hung, Albert Y, Mejia, Nicte, Khurana, Vikram, Gomperts, Stephen N, Selkoe, Dennis J, Schwarzschild, Michael A, Schlossmacher, Michael G, Hyman, Bradley T, Sudarsky, Lewis R, Growdon, John H, Scherzer, Clemens R

“…OBJECTIVE:To conclusively test for a specific association between the biological marker 25-hydroxy-vitamin D3, a transcriptionally active hormone produced in…”
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Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease by Locascio, Joseph J, Eberly, Shirley, Liao, Zhixiang, Liu, Ganqiang, Hoesing, Ashley N, Duong, Karen, Trisini-Lipsanopoulos, Ana, Dhima, Kaltra, Hung, Albert Y, Flaherty, Alice W, Schwarzschild, Michael A, Hayes, Michael T, Wills, Anne-Marie, Shivraj Sohur, U, Mejia, Nicte I, Selkoe, Dennis J, Oakes, David, Shoulson, Ira, Dong, Xianjun, Marek, Ken, Zheng, Bin, Ivinson, Adrian, Hyman, Bradley T, Growdon, John H, Sudarsky, Lewis R, Schlossmacher, Michael G, Ravina, Bernard, Scherzer, Clemens R

“…There are no cures for neurodegenerative diseases and this is partially due to the difficulty of monitoring pathogenic molecules in patients during life. The…”
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Tai Chi for Reducing Dual-task Gait Variability, a Potential Mediator of Fall Risk in Parkinson’s Disease: A Pilot Randomized Controlled Trial by Vergara-Diaz, Gloria, Osypiuk, Kamila, Hausdorff, Jeffrey M, Bonato, Paolo, Gow, Brian J, Miranda, Jose GV, Sudarsky, Lewis R, Tarsy, Daniel, Fox, Michael D, Gardiner, Paula, Thomas, Cathi A, Macklin, Eric A, Wayne, Peter M

“…Objectives To assess the feasibility and inform design features of a fully powered randomized controlled trial (RCT) evaluating the effects of Tai Chi (TC) in…”
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White matter abnormalities in dystonia normalize after botulinum toxin treatment by Blood, Anne J, Tuch, David S, Makris, Nikos, Makhlouf, Miriam L, Sudarsky, Lewis R, Sharma, Nutan

“…The pathophysiology of dystonia is still poorly understood. We used diffusion tensor imaging to screen for white matter abnormalities in regions between the…”
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Association of SNCA with Parkinson: Replication in the Harvard NeuroDiscovery Center Biomarker Study by Ding, Hongliu, Sarokhan, Alison K., Roderick, Sarah S., Bakshi, Rachit, Maher, Nancy E., Ashourian, Paymon, Kan, Caroline G., Chang, Sunny, Santarlasci, Andrea, Swords, Kyleen E., Ravina, Bernard M., Hayes, Michael T., Sohur, U. Shivraj, Wills, Anne-Marie, Flaherty, Alice W., Unni, Vivek K., Hung, Albert Y., Selkoe, Dennis J., Schwarzschild, Michael A., Schlossmacher, Michael G., Sudarsky, Lewis R., Growdon, John H., Ivinson, Adrian J., Hyman, Bradley T., Scherzer, Clemens R.

“…Background: Mutations in the α‐synuclein gene (SNCA) cause autosomal dominant forms of Parkinson's disease, but the substantial risk conferred by this locus to…”
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The utility of laser-generated visual-cueing in Parkinsonian patients with gait freezing by Donovan, Shannon, Lim, Chen, Rose, Peggy, Tarsy, Daniel, Sudarsky, Lewis R, Simon, David K

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Prediction of cognition in Parkinson's disease with a clinical–genetic score: a longitudinal analysis of nine cohorts by Liu, Ganqiang, PhD, Locascio, Joseph J, PhD, Corvol, Jean-Christophe, Prof, Boot, Brendon, MBBS, Liao, Zhixiang, MS, Page, Kara, BS, Franco, Daly, BA, Burke, Kyle, BS, Jansen, Iris E, MS, Trisini-Lipsanopoulos, Ana, BS, Winder-Rhodes, Sophie, PhD, Tanner, Caroline M, Prof, Lang, Anthony E, Prof, Eberly, Shirley, MS, Elbaz, Alexis, Prof, Brice, Alexis, Prof, Mangone, Graziella, MD, Ravina, Bernard, MD, Shoulson, Ira, Prof, Cormier-Dequaire, Florence, MD, Heutink, Peter, Prof, van Hilten, Jacobus J, Prof, Barker, Roger A, Prof, Williams-Gray, Caroline H, PhD, Marinus, Johan, PhD, Scherzer, Clemens R, Dr

“…Summary Background Cognitive decline is a debilitating manifestation of disease progression in Parkinson's disease. We aimed to develop a clinical–genetic…”
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Sudden uncontrollable somnolence and medication use in Parkinson disease by Avorn, Jerry, Schneeweiss, Sebastian, Sudarsky, Lewis R, Benner, Joshua, Kiyota, Yuka, Levin, Raisa, Glynn, Robert J

“…Episodes of sudden uncontrollable somnolence have been reported in patients with Parkinson disease (PD) receiving dopamine agonists, including pramipexole and…”
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Unrecognized vitamin D 3 deficiency is common in Parkinson disease: Harvard Biomarker Study by Ding, Hongliu, Dhima, Kaltra, Lockhart, Kaitlin C., Locascio, Joseph J., Hoesing, Ashley N., Duong, Karen, Trisini-Lipsanopoulos, Ana, Hayes, Michael T., Sohur, U. Shivraj, Wills, Anne-Marie, Mollenhauer, Brit, Flaherty, Alice W., Hung, Albert Y., Mejia, Nicte, Khurana, Vikram, Gomperts, Stephen N., Selkoe, Dennis J., Schwarzschild, Michael A., Schlossmacher, Michael G., Hyman, Bradley T., Sudarsky, Lewis R., Growdon, John H., Scherzer, Clemens R.

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Specific splice variants are associated with Parkinson's disease by Santiago, Jose A., Scherzer, Clemens R., Potashkin, Judith A.

“…ABSTRACT Background Diagnosis of Parkinson's disease (PD) currently relies on assessment of motor symptoms. Recently, sensitive, specific, and readily…”
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Unrecognized vitamin D sub(3) deficiency is common in Parkinson disease: Harvard Biomarker Study by Ding, Hongliu, Dhima, Kaltra, Lockhart, Kaitlin C, Locascio, Joseph J, Hoesing, Ashley N, Duong, Karen, Trisini-Lipsanopoulos, Ana, Hayes, Michael T, Sohur, U Shivraj, Wills, Anne-Marie, Mollenhauer, Brit, Flaherty, Alice W, Hung, Albert Y, Mejia, Nicte, Khurana, Vikram, Gomperts, Stephen N, Selkoe, Dennis J, Schwarzschild, Michael A, Schlossmacher, Michael G, Hyman, Bradley T, Sudarsky, Lewis R, Growdon, John H, Scherzer, Clemens R

“…Objective: To conclusively test for a specific association between the biological marker 25-hydroxy-vitamin D sub(3), a transcriptionally active hormone…”
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Validation of a neurological-exam-based rating scale (FARS) for Friedreich's ataxia by Sudarsky, Lewis R

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O4-06-06 Combined dopamine transporter and FDG pet in DLB, AD, and PD by Johnson, Keith A., Rentz, Dorene M., Moran, Erin K., Becker, John A., Schlossmacher, Michael G., Sudarsky, Lewis R., Fischman, Alan J.

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Abnormal Cisternogram Associated with Diamox Therapy by Papanicolaou, Nicholas, McNeil, Barbara J, Funkenstein, H. Harris, Sudarsky, Lewis R

“…A cisternogram characteristic of normal-pressure hydrocephalus was obtained from a patient on Diamox who was being evaluated for rapid mental deterioration. A…”
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