Search Results - "Suchy, James"

Accessible lab manual for physical therapy students by Reinink, Michelle, Suchy, James, Glasoe, Ward

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Synergy between EphA2-ILs-DTXp, a Novel EphA2-Targeted Nanoliposomal Taxane, and PD-1 Inhibitors in Preclinical Tumor Models by Kamoun, Walid S, Dugast, Anne-Sophie, Suchy, James J, Grabow, Stephanie, Fulton, Ross B, Sampson, James F, Luus, Lia, Santiago, Michael, Koshkaryev, Alexander, Sun, Gang, Askoxylakis, Vasileios, Tam, Eric, Huang, Zhaohua Richard, Drummond, Daryl C, Sawyer, Andrew J

“…Combinations of chemotherapy with immunotherapy have seen recent clinical success, including two approvals of anti-PD-1/L1 agents in combination with…”
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A Tissue Dielectric Constant Evaluation of Knee Edema: A Retrospective Intra-rater Reliability and Association Study of Repeated Measures by Suchy, James P, Glasoe, Ward M, Koehler, Linda A

“…Background: This research compared the reliability and association of tissue dielectric constant (TDC) measures of knee edema to circumferential measurements…”
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Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models by Kamoun, Walid S., Kirpotin, Dmitri B., Huang, Zhaohua Richard, Tipparaju, Suresh K., Noble, Charles O., Hayes, Mark E., Luus, Lia, Koshkaryev, Alexander, Kim, Jaeyeon, Olivier, Ken, Kornaga, Tad, Oyama, Shinji, Askoxylakis, Vasileios, Pien, Christine, Kuesters, Geoffrey, Dumont, Nancy, Lugovskoy, Alexey A., Schihl, Sarah A., Wilton, John H., Geddie, Melissa L., Suchy, James, Grabow, Stephanie, Kohli, Neeraj, Reynolds, C. Patrick, Blaydes, Rachel, Zhou, Yu, Sawyer, Andrew J., Marks, James D., Drummond, Daryl C.

“…Antibody-mediated tumour targeting and nanoparticle-mediated encapsulation can reduce the toxicity of antitumour drugs and improve their efficacy. Here, we…”
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Host-Seeking Behavior in the Bed Bug, Cimex lectularius by Suchy, James T, Lewis, Vernard R

“…The reemergence of the bed bug, Cimex lectularius Linnaeus, has recently spawned a frenzy of public, media, and academic attention. In response to the growing…”
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A Real Pain in the Neck: A Football Player with Atypical Post-Traumatic Neck Pain: 2175 Board #331 May 30 3:30 PM - 5:00 PM by Suchy, James, McKeag, Doug

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Application of PAT Tools for the Safe and Reliable Production of a Dihydro-1H-imidazole by Barrios Sosa, Ana C., Conway, Ryan, Williamson, R. Thomas, Suchy, James P., Edwards, William, Cleary, Thomas

“…The application of two Process Analytical Technology (PAT) tools was studied and implemented for the safe and reliable synthesis of an advanced intermediate…”
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Abstract 2491: Engineering and preclinical activity of MM-201, a best-in-class TRAIL receptor agonist by Sawyer, Andrew J., Ghassemifar, Sara, Wong, Christina, Richards, Jennifer, Grabow, Stephanie, Suchy, James, Koshkaryev, Alexander, Razlog, Maja, Tam, Eric, Drummond, Daryl C.

“…Early attempts at using TNF superfamily members for anticancer therapies, TNF and FAS, led to serious systemic toxicities. However, the discovery of tumor…”
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Abstract 4846: MM-401, a novel anti-TNFR2 antibody that induces T cell co-stimulation, robust anti-tumor activity and immune memory by Richards, Jennifer, Wong, Christina, Koshkaryev, Alexander, Fulton, Ross, Camblin, Adam, Sampson, James, Luus, Lia, Suchy, James, Grabow, Stephanie, Kurella, Vinodh, Kumar, Sandeep, Lulo, James, Qiu, James, Jiao, Yang, Xu, Lihui, Paragas, Violette, Razlog, Maja, Muda, Marco, Tam, Eric, Raue, Andreas, Drummond, Daryl

“…TNFR2 has been implicated as a novel target for cancer immunotherapy. While TNFR2 has been linked to enhanced suppressive activity of regulatory T cells…”
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Abstract 555: A novel human TNFR2 antibody (MM-401) modulates T cell responses in anti-cancer immunity by Sampson, James F., Kurella, Vinodh B., Paragas, Violette, Kumar, Sandeep, Lulo, James E., Qiu, James A., Razlog, Maja, Fulton, Ross B., Camblin, Adam J., Richards, Jennifer M., Wong, Christina S., Koshkaryev, Alexander, Suchy, James J., Grabow, Stephanie, Muda, Marco, Raue, Andreas, Drummond, Daryl C., Tam, Eric M.

“…TNFR2 is an emerging therapeutic target in immuno-oncology. We have previously shown that an agonistic mouse TNFR2 antibody was able to activate CD8+ T cells…”
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A novel TNFR2 antibody induces T cell co-stimulation and promotes durable anti-tumor immunity by Sampson, James F, Fulton, Ross B, Kurella, Vinodh B, Richards, Jennifer M, Camblin, Adam J, Wong, Christina S, Koshkaryev, Alexander, Lulo, James E, Qiu, James A, Kumar, Sandeep, Luus, Lia, Jiao, Yang, Suchy, James, Grabow, Stephanie, Paragas, Violette, Razlog, Maja, Xi, Lihui, Muda, Marco, Drummond, Daryl C, Tam, Eric M, Raue, Andreas

“…TNFR2, an emerging therapeutic target in immuno-oncology, is upregulated upon T cell activation and is expressed by tumor-infiltrating effector and regulatory…”
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Dietary supplementation with a combination of α -lipoic acid, acetyl- l -carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance by Suchy, James, Chan, Amy, Shea, Thomas B

“…Abstract Alzheimer disease has a complex etiology composed of nutritional and genetic risk factors and predispositions. Moreover, genetic risk factors for…”
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Application of PAT Tools for the Safe and Reliable Production of a Dihydro-1 H -imidazole by Barrios Sosa, Ana C., Conway, Ryan, Williamson, R. Thomas, Suchy, James P., Edwards, William, Cleary, Thomas

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Dietary Supplementation with S-Adenosyl Methionine Delays the Onset of Motor Neuron Pathology in a Murine Model of Amyotrophic Lateral Sclerosis by Suchy, James, Lee, Sangmook, Ahmed, Ambar, Shea, Thomas B.

“…The full range of causative factors in Amyotrophic lateral sclerosis (ALS) remains elusive, but oxidative stress is recognized as a contributing factor…”
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Dietary supplementation with a combination of α-lipoic acid, acetyl-L-camitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance by SUCHY, James, CHAN, Amy, SHEA, Thomas B

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Effects of nutritional supplementation on the progression of motor neuron degeneration in a murine model of amyotrophic lateral sclerosis by Suchy, James J

“…Amyotrophic lateral sclerosis (ALS) is a fatal disorder characterized by a loss of motor neurons that causes muscle degeneration. Factors remain elusive but…”
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Effect of nutritional supplementation on progression of motor neuron disease by Suchy, James Joseph

“…Amyotrophic lateral sclerosis (ALS), otherwise known as motor neuron disease (MND), is an invariably fatal, age-related disorder characterized by a progressive…”
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