Search Results - "Suchiman, H.E.D."

Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls by Bot, Mariska, Milaneschi, Yuri, Al-Shehri, Tahani, Amin, Najaf, Garmaeva, Sanzhima, Onderwater, Gerrit L.J., Pool, Rene, Thesing, Carisha S., Vijfhuizen, Lisanne S., Vogelzangs, Nicole, Arts, Ilja C.W., Demirkan, Ayse, van Duijn, Cornelia, van Greevenbroek, Marleen, van der Kallen, Carla J.H., Köhler, Sebastian, Ligthart, Lannie, van den Maagdenberg, Arn M.J.M., Mook-Kanamori, Dennis O., de Mutsert, Renée, Tiemeier, Henning, Schram, Miranda T., Stehouwer, Coen D.A., Terwindt, Gisela M., Willems van Dijk, Ko, Fu, Jingyuan, Zhernakova, Alexandra, Beekman, Marian, Slagboom, P. Eline, Boomsma, Dorret I., Penninx, Brenda W.J.H., Beekman, M., Suchiman, H.E.D., Deelen, J., Amin, N., Beulens, J.W., van der Bom, J.A., Bomer, N., Demirkan, A., van Hilten, J.A., Meessen, J.M.T.A., Pool, R., Moed, M.H., Fu, J., Onderwater, G.L.J., Rutters, F., So-Osman, C., van der Flier, W.M., van der Heijden, A.A.W.A., van der Spek, A., Asselbergs, F.W., Boersma, E., Elders, P.M., Geleijnse, J.M., Ikram, M.A., Kloppenburg, M., Meulenbelt, I., Mooijaart, S.P., Nelissen, R.G.H.H., Netea, M.G., Penninx, B.W.J.H., Stehouwer, C.D.A., Teunissen, C.E., Terwindt, G.M., ’t Hart, L.M., van den Maagdenberg, A.M.J.M., van der Harst, P., van der Horst, I.C.C., van der Kallen, C.J.H., van Greevenbroek, M.M.J., van Spil, W.E., Wijmenga, C., Zwinderman, A.H., Zhernikova, A., Jukema, J.W., Sattar, N.

“…Depression has been associated with metabolic alterations, which adversely impact cardiometabolic health. Here, a comprehensive set of metabolic markers,…”
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Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin by Houtman, E., Coutinho de Almeida, R., Tuerlings, M., Suchiman, H.E.D., Broekhuis, D., Nelissen, R.G.H.H., Ramos, Y.F.M., van Meurs, J.B.J., Meulenbelt, I.

“…We here aimed to characterize changes of Matrix Gla Protein (MGP) expression in relation to its recently identified OA risk allele rs1800801-T in OA cartilage,…”
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WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes by Tuerlings, M., Janssen, G.M.C., Boone, I., van Hoolwerff, M., Rodriguez Ruiz, A., Houtman, E., Suchiman, H.E.D., van der Wal, R.J.P., Nelissen, R.G.H.H., Coutinho de Almeida, R., van Veelen, P.A., Ramos, Y.F.M., Meulenbelt, I.

“…To explore the co-expression network of the osteoarthritis (OA) risk gene WWP2 in articular cartilage and study cartilage characteristics when mimicking the…”
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Higher thyroid stimulating hormone leads to cardiovascular disease and an unfavorable lipid profile: EVidence from multi-cohort Mendelian randomization and metabolomic profiling by Van Vliet, N.A., Bos, M.M., Thesing, C.S., Chaker, L., Pietzner, M., Houtman, E., Neville, M.J., Li-Gao, R., Trompet, S., Mustafa, R., Ahmadizar, F., Beekman, M., Bot, M., Budde, K., Christodoulides, C., Dehghan, A., Delles, C., Elliott, P., Evangelou, M., Gao, H., Ghanbari, M., Van Herwaarden, A.E., Ikram, M.A., Jaeger, M., Jukema, J.W., Karaman, I., Karpe, F., Kloppenburg, M., Meessen, J.M.T.A., Meulenbelt, I., Milaneschi, Y., Mooijaart, S.P., Mook-Kanamori, D.O., Netea, M.G., Netea-Maier, R.T., Peeters, R.P., Penninx, B.W.J.H., Sattar, N., Slagboom, P.E., Suchiman, H.E.D., Völzke, H., Van Dijk, K. Willems, Noordam, R.

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NMR metabolomics-guided DNA methylation mortality predictors by Bizzarri, Daniele, Reinders, Marcel J.T., Kuiper, Lieke, Beekman, Marian, Deelen, Joris, van Meurs, Joyce B.J., van Dongen, Jenny, Pool, René, Boomsma, Dorret I., Ghanbari, Mohsen, Franke, Lude, Geleijnse, J.M., Boersma, E., van Spil, W.E., van Greevenbroek, M.M.J., Stehouwer, C.D.A., van der Kallen, C.J.H., Arts, I.C.W., Rutters, F., Beulens, J.W.J., Muilwijk, M., Elders, P.J.M., 't Hart, L.M., Ghanbari, M., Ikram, M.A., Netea, M.G., Kloppenburg, M., Ramos, Y.F.M., Bomer, N., Meulenbelt, I., Stronks, K., Snijder, M.B., Zwinderman, A.H., Heijmans, B.T., Lumey, L.H., Wijmenga, C., Fu, J., Zhernakova, A., Deelen, J., Mooijaart, S.P., Beekman, M., Slagboom, P.E., Onderwater, G.L.J., van den Maagdenberg, A.M.J.M., Terwindt, G.M., Thesing, C., Bot, M., Penninx, B.W.J.H., Trompet, S., Jukema, J.W., Sattar, N., van der Horst, I.C.C., van der Harst, P., So-Osman, C., van Hilten, J.A., Nelissen, R.G.H.H., Höfer, I.E., Asselbergs, F.W., Scheltens, P., Teunissen, C.E., van der Flier, W.M., van Dongen, J., Pool, R., Willemsen, A.H.M., Boomsma, D.I., Suchiman, H.E.D., Barkey Wolf, J.J.H., Cats, D., Mei, H., Slofstra, M., Swertz, M., Reinders, M.J.T., van den Akker, E.B., Slagboom, Pieternella E., van den Akker, Erik B.

“…1H-NMR metabolomics and DNA methylation in blood are widely known biomarkers predicting age-related physiological decline and mortality yet exert mutually…”
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NMR metabolomics-guided DNA methylation mortality predictorsResearch in context by Daniele Bizzarri, Marcel J.T. Reinders, Lieke Kuiper, Marian Beekman, Joris Deelen, Joyce B.J. van Meurs, Jenny van Dongen, René Pool, Dorret I. Boomsma, Mohsen Ghanbari, Lude Franke, Pieternella E. Slagboom, Erik B. van den Akker, J.M. Geleijnse, E. Boersma, W.E. van Spil, M.M.J. van Greevenbroek, C.D.A. Stehouwer, C.J.H. van der Kallen, I.C.W. Arts, F. Rutters, J.W.J. Beulens, M. Muilwijk, P.J.M. Elders, L.M. 't Hart, M. Ghanbari, M.A. Ikram, M.G. Netea, M. Kloppenburg, Y.F.M. Ramos, N. Bomer, I. Meulenbelt, K. Stronks, M.B. Snijder, A.H. Zwinderman, B.T. Heijmans, L.H. Lumey, C. Wijmenga, J. Fu, A. Zhernakova, J. Deelen, S.P. Mooijaart, M. Beekman, P.E. Slagboom, G.L.J. Onderwater, A.M.J.M. van den Maagdenberg, G.M. Terwindt, C. Thesing, M. Bot, B.W.J.H. Penninx, S. Trompet, J.W. Jukema, N. Sattar, I.C.C. van der Horst, P. van der Harst, C. So-Osman, J.A. van Hilten, R.G.H.H. Nelissen, I.E. Höfer, F.W. Asselbergs, P. Scheltens, C.E. Teunissen, W.M. van der Flier, J. van Dongen, R. Pool, A.H.M. Willemsen, D.I. Boomsma, H.E.D. Suchiman, J.J.H. Barkey Wolf, D. Cats, H. Mei, M. Slofstra, M. Swertz, M.J.T. Reinders, E.B. van den Akker

“…Background: 1H-NMR metabolomics and DNA methylation in blood are widely known biomarkers predicting age-related physiological decline and mortality yet exert…”
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RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets by Tuerlings, Margo, Hoolwerff, Marcella, Houtman, Evelyn, Suchiman, Eka H. E. D., Lakenberg, Nico, Mei, Hailiang, Linden, Enrike H. M. J., Nelissen, Rob R. G. H. H., Ramos, Yolande Y. F. M., Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid

“…Objective To identify key determinants of the interactive pathophysiologic processes in subchondral bone and cartilage in osteoarthritis (OA). Methods We…”
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Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants by Houtman, Evelyn, Tuerlings, Margo, Riechelman, Janne, Suchiman, Eka H. E. D, van der Wal, Robert J. P, Nelissen, Rob G. H. H, Mei, Hailiang, Ramos, Yolande F. M, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid

“…Abstract Background Failing of intrinsic chondrocyte repair after mechanical stress is known as one of the most important initiators of osteoarthritis…”
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