Search Results - "Such, Georgina K."

The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery by Smith, Samuel A, Selby, Laura I, Johnston, Angus P. R, Such, Georgina K

“…Many emerging therapies rely on the delivery of biological cargo into the cytosol. Nanoparticle delivery systems hold great potential to deliver these…”
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pH‐Responsive Polymer Nanoparticles for Drug Delivery by Deirram, Nayeleh, Zhang, Changhe, Kermaniyan, Sarah S., Johnston, Angus P. R., Such, Georgina K.

“…Stimuli‐responsive nanoparticles have the potential to improve the delivery of therapeutics to a specific cell or region within the body. There are many…”
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One-Step Assembly of Coordination Complexes for Versatile Film and Particle Engineering by Ejima, Hirotaka, Richardson, Joseph J., Liang, Kang, Best, James P., van Koeverden, Martin P., Such, Georgina K., Cui, Jiwei, Caruso, Frank

“…The development of facile and versatile strategies for thin-film and particle engineering is of immense scientific interest. However, few methods can…”
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Immobilization and Intracellular Delivery of an Anticancer Drug Using Mussel-Inspired Polydopamine Capsules by Cui, Jiwei, Yan, Yan, Such, Georgina K, Liang, Kang, Ochs, Christopher J, Postma, Almar, Caruso, Frank

“…We report a facile approach to immobilize pH-cleavable polymer-drug conjugates in mussel-inspired polydopamine (PDA) capsules for intracellular drug delivery…”
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Interfacing Materials Science and Biology for Drug Carrier Design by Such, Georgina K., Yan, Yan, Johnston, Angus P. R., Gunawan, Sylvia T., Caruso, Frank

“…Over the last ten years, there has been considerable research interest in the development of polymeric carriers for biomedicine. Such delivery systems have the…”
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Nanoescapology: progress toward understanding the endosomal escape of polymeric nanoparticles by Selby, Laura I., Cortez‐Jugo, Christina M., Such, Georgina K., Johnston, Angus P.R.

“…Using nanoparticles to deliver drugs to cells has the potential to revolutionize the treatment of many diseases, including HIV, cancer, and diabetes. One of…”
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Engineering Particles for Therapeutic Delivery: Prospects and Challenges by Yan, Yan, Such, Georgina K, Johnston, Angus P. R, Best, James P, Caruso, Frank

“…Nanoengineered particles that can facilitate drug formulation and passively target tumors have reached the clinic in recent years. These early successes have…”
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Synthesis and functionalization of nanoengineered materials using click chemistry by Such, Georgina K., Johnston, Angus P.R., Liang, Kang, Caruso, Frank

“…The synthesis of nanoengineered materials with precise control over material composition, architecture and functionality is integral to advances in diverse…”
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Assembly of Ultrathin Polymer Multilayer Films by Click Chemistry by Such, Georgina K, Quinn, John F, Quinn, Anthony, Tjipto, Elvira, Caruso, Frank

“…Layer-by-layer (LbL) assembly is a versatile and robust technique for fabricating tailored thin films of diverse composition. Herein we report a new method of…”
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Multifunctional Thrombin-Activatable Polymer Capsules for Specific Targeting to Activated Platelets by Gunawan, Sylvia T., Kempe, Kristian, Bonnard, Thomas, Cui, Jiwei, Alt, Karen, Law, Lok S., Wang, Xiaowei, Westein, Erik, Such, Georgina K., Peter, Karlheinz, Hagemeyer, Christoph E., Caruso, Frank

“…Smart poly(2‐oxazoline) (POx)‐based multifunctional polymer capsules that specifically target glycoprotein (GP) IIb/IIIa on the surface of activated platelets…”
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Next generation, sequentially assembled ultrathin films: beyond electrostatics by Quinn, John F, Johnston, Angus P R, Such, Georgina K, Zelikin, Alexander N, Caruso, Frank

“…Over the last 15 years, the layer-by-layer (LbL) assembly technology has proven to be a versatile method for surface modification. This approach is likely to…”
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Triggering Release of Encapsulated Cargo by Johnston, Angus P. R., Such, Georgina K., Caruso, Frank

“…Specific stimuli can be used to trigger the release of cargo encapsulated in polymer carriers in applications ranging from drug delivery to catalysis. Current…”
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Ultrathin, Responsive Polymer Click Capsules by Such, Georgina K., Tjipto, Elvira, Postma, Almar, Johnston, Angus P. R., Caruso, Frank

“…We report a general click chemistry approach for the layer-by-layer assembly of ultrathin, polymer films on particles and the subsequent formation of polymer…”
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Targeting of Cancer Cells Using Click-Functionalized Polymer Capsules by Kamphuis, Marloes M. J, Johnston, Angus P. R, Such, Georgina K, Dam, Henk H, Evans, Richard A, Scott, Andrew M, Nice, Edouard C, Heath, Joan K, Caruso, Frank

“…Targeted delivery of drugs to specific cells allows a high therapeutic dose to be delivered to the target site with minimal harmful side effects. Combining…”
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Low-Fouling, Biofunctionalized, and Biodegradable Click Capsules by Ochs, Christopher J, Such, Georgina K, Städler, Brigitte, Caruso, Frank

“…We report the synthesis of covalently stabilized hollow capsules from biodegradable materials using a combination of click chemistry and layer-by-layer (LbL)…”
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Tuning the Properties of Layer-by-Layer Assembled Poly(acrylic acid) Click Films and Capsules by Kinnane, Cameron R, Such, Georgina K, Caruso, Frank

“…The combination of click chemistry and layer-by-layer (LbL) assembly provides a useful and convenient means of preparing functional, covalently stabilized…”
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The generic enhancement of photochromic dye switching speeds in a rigid polymer matrix by Evans, Richard A, Hanley, Tracey L, Skidmore, Melissa A, Davis, Thomas P, Such, Georgina K, Yee, Lachlan H, Ball, Graham E, Lewis, David A

“…The switching or isomerization speed of photochromic dyes in a rigid polymeric matrix (such as an ophthalmic lens) is generally significantly slower than that…”
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Assembly and Degradation of Low-Fouling Click-Functionalized Poly(ethylene glycol)-Based Multilayer Films and Capsules by Leung, Melissa K. M., Such, Georgina K., Johnston, Angus P. R., Biswas, Dhee P., Zhu, Zhiyuan, Yan, Yan, Lutz, Jean-François, Caruso, Frank

“…Nano‐/micrometer‐scaled films and capsules made of low‐fouling materials such as poly(ethylene glycol) (PEG) are of interest for drug delivery and tissue…”
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Polyoxometalates as chemically and structurally versatile components in self-assembled materials by Gao, Yanting, Choudhari, Manjiri, Such, Georgina K, Ritchie, Chris

“…Polyoxometalates (POMs) are anionic molecular metal oxides with expansive diversity in terms of their composition, structure, nuclearity and charge. Within…”
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Surface “Click” Chemistry on Brominated Plasma Polymer Thin Films by Chen, Rodney T, Muir, Benjamin W, Such, Georgina K, Postma, Almar, Evans, Richard A, Pereira, Suzanne M, McLean, Keith M, Caruso, Frank

“…A brominated plasma polymer (BrPP) thin film was fabricated on a variety of substrate surfaces (silicon wafers, glass, gold, and polymers) via the radio…”
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