Search Results - "Subudhi, Umakanta"
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Self-assembled DNA nanostructure containing oncogenic miRNA-mediated cell proliferation by downregulation of FOXO1 expression
Published in BMC cancer (20-12-2022)“…FOXO1 transcription factor not only limits the cell cycle progression but also promotes cell death as a tumor suppressor protein. Though the expression of…”
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2
Lanthanum induced B-to-Z transition in self-assembled Y-shaped branched DNA structure
Published in Scientific reports (31-05-2016)“…Controlled conversion of right-handed B-DNA to left-handed Z-DNA is one of the greatest conformational transitions in biology. Recently, the B-Z transition has…”
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3
Prospective role of thyroid disorders in monitoring COVID-19 pandemic
Published in Heliyon (01-12-2020)“…COVID-19 pandemic has affected more than 200 countries and 1.3 million individuals have deceased within eleven months. Intense research on COVID-19 occurrence…”
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4
Differential desulfurization of dibenzothiophene by newly identified MTCC strains: Influence of Operon Array
Published in PloS one (08-03-2018)“…Since the sulfur specific cleavage is vital for the organic sulfur removal from fossil fuel, we explored potential bacterial strains of MTCC (Microbial Type…”
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5
Supplementation of curcumin and vitamin E enhances oxidative stress, but restores hepatic histoarchitecture in hypothyroid rats
Published in Life sciences (1973) (13-03-2009)“…In the present study, the effects of vitamin E and curcumin on hepatic dysfunction, mitochondrial oxygen consumption as well as hyperlipidemia in hypothyroid…”
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Modulation of antioxidant enzyme by light and heavy rare earth metals: A case study with catalase
Published in International journal of biological macromolecules (01-11-2024)Get full text
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7
DNA polyhedrons cube, prism, and square pyramid protect the catalytic activity of catalase: A thermodynamics and kinetics study
Published in International journal of biological macromolecules (01-04-2024)“…DNA is widely used as building block material for the construction of polyhedral nanostructures. DNA polyhedrons (DNA prism, cube, and square pyramid) are…”
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8
Minimum number of oligonucleotide-based stable monomeric branched DNA nanostructure: Biochemical and biophysical study
Published in International journal of biological macromolecules (01-09-2024)“…DNA has been employed as building blocks for the construction of nanomaterials due to their programmability and wide range applications. The functional…”
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9
Alterations in expression of senescence marker protein-30 gene by 3,3',5-triiodo-l-thyronine (T₃)
Published in Molecular and cellular biochemistry (01-09-2007)“…Thyroid hormone (T₃) is essential for normal development, differentiation, and metabolic balance of the body. A toxic dose of T₃ in animals increases the basal…”
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10
Biophysical interaction between self-assembled branched DNA nanostructures with bovine serum albumin and bovine liver catalase
Published in International journal of biological macromolecules (30-04-2021)“…Branched DNA (bDNA) nanostructures have emerged as self-assembled biomaterials and are being considered for biomedical applications. Herein, we report the…”
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11
Biochemical and biophysical interaction of rare earth elements with biomacromolecules: A comprehensive review
Published in Chemosphere (Oxford) (01-06-2024)“…The growing utilization of rare earth elements (REEs) in industrial and technological applications has captured global interest, leading to the development of…”
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Enhanced enzymatic activity and conformational stability of catalase in presence of tetrahedral DNA nanostructures: A biophysical and kinetic study
Published in International journal of biological macromolecules (01-07-2023)“…The emergence of DNA nanotechnology has shown enormous potential in a vast array of applications, particularly in the medicinal and theranostics fields…”
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13
Differential interaction of cerium chloride with bovine liver catalase: A computational and biophysical study
Published in Chemosphere (Oxford) (01-01-2020)“…In this study, Cerium chloride-induced conformational changes of Bovine Liver Catalase (BLC) has been investigated by molecular docking and further supported…”
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14
Zeta potential of Z-DNA: A new signature to study B-Z transition in linear and branched DNA
Published in International journal of biological macromolecules (01-05-2024)“…Zeta potential is commonly referred as surface charge density and is a key factor in modulating the structural and functional properties of nucleic acids…”
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Molecular interaction of benzo-a-pyrene inhibits the catalytic activity of catalase: Insights from biophysical and computational studies
Published in Journal of molecular structure (05-10-2022)“…•Molecular docking and simulation supports the direct binding of BaP with BLC.•Interaction of BaP with BLC decreases α-helix and increases other secondary…”
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Preparation of Stable Branched DNA Nanostructures: Process of Cooperative Self-Assembly
Published in The journal of physical chemistry. B (02-05-2019)“…The construction of functionalizable branched DNA (bDNA) relies on the designing of oligonucleotides and exploitation of their complementary chemistries. The…”
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Sequence-specific B-to-Z transition in self-assembled DNA: A biophysical and thermodynamic study
Published in International journal of biological macromolecules (15-09-2019)“…The most remarkable conformational transition in nature is the B-to-Z transition of DNA which not only contributes for epigenetic regulation but also is…”
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Molecular self-assembly of stable and small branched DNA nanostructures: Higher than a helical turn is enough for hybridization
Published in International journal of biological macromolecules (01-12-2024)“…The Watson-Crick base pairing property of DNA is widely used for fabricating DNA nanostructures with well-defined geometry. Moreover, DNA nanostructures can be…”
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Praseodymium promotes B-Z transition in self-assembled DNA nanostructures
Published in RSC advances (01-01-2019)“…Millimolar concentrations of PrCl can induce sequence-specific B-Z transition in various-self-assembled branched DNA (bDNA) nanostructures. Competitive dye…”
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20
Thermodynamics of benzoquinone-induced conformational changes in nucleic acids and human serum albumin
Published in Chemico-biological interactions (05-01-2023)“…Biological macromolecules such as proteins, nucleic acids, carbohydrates and lipids, play a crucial role in biochemical and molecular processes. Thus, the…”
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