Search Results - "Subtil, Fernanda Teixeira"
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New insights into the SAR and drug combination synergy of 2-(quinolin-4-yloxy)acetamides against Mycobacterium tuberculosis
Published in European journal of medicinal chemistry (27-01-2017)“…2-(Quinolin-4-yloxy)acetamides have been described as potent and selective in vitro inhibitors of Mycobacterium tuberculosis (Mtb) growth. Herein, a new series…”
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1H-Benzo[d]imidazoles and 3,4-dihydroquinazolin-4-ones: Design, synthesis and antitubercular activity
Published in European journal of medicinal chemistry (15-07-2018)“…Using a classical hybridization approach, a series of 1H-benzo[d]imidazoles and 3,4-dihydroquinazolin-4-ones were synthesized (39 examples) and evaluated as…”
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Activity of 2-(quinolin-4-yloxy)acetamides in Mycobacterium tuberculosis clinical isolates and identification of their molecular target by whole-genome sequencing
Published in International journal of antimicrobial agents (01-03-2018)“…•Quinoloxyacetamides are active against clinical isolates resistant to main tuberculosis (TB) drugs.•Quinoloxyacetamides do not target DNA gyrase from…”
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Thermodynamics, functional and structural characterization of inosine–uridine nucleoside hydrolase from Leishmania braziliensis
Published in RSC advances (2017)“…Leishmaniasis is considered one of the main endemic diseases in the world, and Brazil is among the countries with the highest incidence of cutaneous and…”
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Thermodynamics, functional and structural characterization of inosine-uridine nucleoside hydrolase from Leishmania braziliensisElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ra07268f
Published 17-10-2017“…Leishmaniasis is considered one of the main endemic diseases in the world, and Brazil is among the countries with the highest incidence of cutaneous and…”
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Journal Article