Search Results - "Subramaniyam, Meera"

The Enhanced Functionality of Low-Affinity CD19 CAR T Cells Is Associated with Activation Priming and Polyfunctional Cytokine Phenotype by Michelozzi, Ilaria M., Gomez-Castaneda, Eduardo, Pohle, Ruben V.C., Cardoso Rodriguez, Ferran, Sufi, Jahangir, Puigdevall, Pau, Subramaniyam, Meera, Wu, Si Wei, Guvenel, Aleks, Ghorashian, Sara, Pule, Martin, Tape, Christopher J., Castellano, Sergi, Amrolia, Persis J, Giustacchini, Alice

“…We have recently described a low-affinity second-generation anti-CD19 Chimeric Antigen Receptor (CAR) (CAT), characterized by faster antigen dissociation rate…”
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Immunotherapy with CD25/CD71-allodepleted T cells to improve T-cell reconstitution after matched unrelated donor hematopoietic stem cell transplant: a randomized trial by Peggs, Karl S., Albon, Sarah J., Oporto Espuelas, Macarena, Irving, Catherine, Richardson, Rachel, Casanovas-Company, Joan, Wallace, Rebecca, Guvenel, Aleks, Ghorashian, Sara, Collura, Angela, Subramaniyam, Meera, Flutter, Barry, Popova, Bilyana, Castro, Fernanda, Lopes, Andre, Champion, Kim, Schofield, Oliver, Clifton-Hadley, Laura, Taylor, Thomas, Farrell, Maria, Adams, Stuart, Gilmour, Kimberly C., Mackinnon, Stephen, Tholouli, Eleni, Amrolia, Persis J.

“…Delayed immune reconstitution is a major challenge after matched unrelated donor (MUD) stem cell transplant (SCT). In this randomized phase 2 multi-center…”
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T-Cell Reconstitution after Unrelated Donor HSCT Using Immunotherapy with CD25/71 Allodepleted Donor T Cells: Results of the Randomised Icat Study by Peggs, Karl S, Albon, Sarah J, Irving, Catherine, Richardson, Rachel, Casanovas-Company, Joan, Wallace, Rebecca, Guvenel, Aleks, Ghorashian, Sara, Collura, Angela, Subramaniyam, Meera, Flutter, Barry, Popova, Bilyana, Castro, Fernanda, Lopes, Andre, Champion, Kim, Schofield, Oliver, Clifton-Hadley, Laura, Taylor, Thomas, Pulham, Timothy, Ings, Stuart, Herlihy, Robert, Farrell, Maria, Wilding, Rachael, Ogden, Wendy, Adams, Stuart, Ahsan, Gulrukh, Gilmour, Kimberly C, Mackinnon, Stephen, Tholouli, Eleni, Amrolia, Persis J

“…Karl S Peggs and Sarah J Albon contributed equally to the work and are joint first author Introduction Alemtuzumab reduces the incidence of GVHD after…”
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Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells by Michelozzi, Ilaria M., Gomez-Castaneda, Eduardo, Pohle, Ruben V. C., Cardoso Rodriguez, Ferran, Sufi, Jahangir, Puigdevall Costa, Pau, Subramaniyam, Meera, Kirtsios, Efstratios, Eddaoudi, Ayad, Wu, Si Wei, Guvenel, Aleks, Fisher, Jonathan, Ghorashian, Sara, Pule, Martin A., Tape, Christopher J., Castellano, Sergi, Amrolia, Persis J., Giustacchini, Alice

“…•Low-affinity CAT CAR T cells are characterized by a unique pattern of activation priming and cytokine polyfunctionality.•The enhanced functionality of…”
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