Search Results - "Subramanian, Sailakshmi"
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The Cochaperone Shutdown Defines a Group of Biogenesis Factors Essential for All piRNA Populations in Drosophila
Published in Molecular cell (28-09-2012)“…In animal gonads, PIWI proteins and their bound 23–30 nt piRNAs guard genome integrity by the sequence specific silencing of transposons. Two branches of piRNA…”
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A Role for Fkbp6 and the Chaperone Machinery in piRNA Amplification and Transposon Silencing
Published in Molecular cell (28-09-2012)“…Epigenetic silencing of transposons by Piwi-interacting RNAs (piRNAs) constitutes an RNA-based genome defense mechanism. Piwi endonuclease action amplifies the…”
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A Small-RNA Enhancer of Viral Polymerase Activity
Published in Journal of Virology (01-12-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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De novo mutations in histone-modifying genes in congenital heart disease
Published in Nature (London) (13-06-2013)“…Exome sequencing of patients with congenital heart disease (CHD) and their unaffected parents reveals an excess of strong-effect, protein-altering de novo…”
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MiST: a new approach to variant detection in deep sequencing datasets
Published in Nucleic acids research (01-09-2013)“…MiST is a novel approach to variant calling from deep sequencing data, using the inverted mapping approach developed for Geoseq. Reads that can map to a…”
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