Search Results - "Subramaniam, V V"

Cancer: The role of iron and ferroptosis by Rishi, Gautam, Huang, Gary, Subramaniam, V. Nathan

“…Iron is an essential element for virtually all living things. Body iron levels are tightly controlled as both increased iron levels and iron deficiency are…”
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The liver in regulation of iron homeostasis by Rishi, Gautam, Subramaniam, V Nathan

“…The liver is one of the largest and most functionally diverse organs in the human body. In addition to roles in detoxification of xenobiotics, digestion,…”
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Hepcidin: regulation of the master iron regulator by Rishi, Gautam, Wallace, Daniel F, Subramaniam, V Nathan

“…Iron, an essential nutrient, is required for many diverse biological processes. The absence of a defined pathway to excrete excess iron makes it essential for…”
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Iron and non-alcoholic fatty liver disease by Britton, Laurence J, Subramaniam, V Nathan, Crawford, Darrell Hg

“…The mechanisms that promote liver injury in non-alcoholic fatty liver disease(NAFLD) are yet to be thoroughly elucidated. As such, effective treatment…”
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Phenotypic analysis of hemochromatosis subtypes reveals variations in severity of iron overload and clinical disease by Sandhu, Kam, Flintoff, Kaledas, Chatfield, Mark D., Dixon, Jeannette L., Ramm, Louise E., Ramm, Grant A., Powell, Lawrie W., Subramaniam, V. Nathan, Wallace, Daniel F.

“…The clinical progression of HFE-related hereditary hemochromatosis (HH) and its phenotypic variability has been well studied. Less is known about the natural…”
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Copper oxide-based cathode for direct NADPH regeneration by Kadowaki, J. T., Jones, T. H., Sengupta, A., Gopalan, V., Subramaniam, V. V.

“…Nearly a fourth of all enzymatic activities is attributable to oxidoreductases, and the redox reactions supported by this vast catalytic repertoire sustain…”
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The global prevalence of HFE and non-HFE hemochromatosis estimated from analysis of next-generation sequencing data by Wallace, Daniel F., Subramaniam, V. Nathan

“…The prevalence of HFE-related hereditary hemochromatosis (HH) among European populations has been well studied. There are no prevalence data for atypical forms…”
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Hemochromatosis: Evaluation of the dietary iron model and regulation of hepcidin by Rishi, Gautam, Secondes, Eriza S., Nathan Subramaniam, V.

“…Our knowledge of iron homeostasis has increased steadily over the last two decades; much of this has been made possible through the study of animal models of…”
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Complications of Temporary Percutaneous Mechanical Circulatory Support for Cardiogenic Shock: An Appraisal of Contemporary Literature by Subramaniam, Anna V., Barsness, Gregory W., Vallabhajosyula, Saarwaani, Vallabhajosyula, Saraschandra

“…Cardiogenic shock (CS) is associated with hemodynamic compromise and end-organ hypoperfusion due to a primary cardiac etiology. In addition to vasoactive…”
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The relationship between systemic iron homeostasis and erythropoiesis by Rishi, Gautam, Subramaniam, V Nathan

“…Red blood cell production (erythropoiesis) is the single largest consumer of iron in the body; this need is satisfied by maintaining a sensitive regulation of…”
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Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload by Wallace, Daniel F., Summerville, Lesa, Crampton, Emily M., Frazer, David M., Anderson, Gregory J., Subramaniam, V. Nathan

“…Hepcidin is a central regulator of iron homeostasis. HFE and transferrin receptor 2 (TFR2) are mutated in adult‐onset forms of hereditary hemochromatosis and…”
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Effects of iron overload in human joint tissue explant cultures and animal models by Prasadam, Indira, Schrobback, Karsten, Kranz-Rudolph, Bastian, Fischer, Nadine, Sonar, Yogita, Sun, Antonia RuJia, Secondes, Eriza, Klein, Travis, Crawford, Ross, Subramaniam, V. Nathan, Rishi, Gautam

“…Osteoarthritis (OA) is a prevalent degenerative joint disease affecting over 530 million individuals worldwide. Recent studies suggest a potential link between…”
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Salmonella enteritidis in a Green Anaconda (Eunectes mutinous): A case study in Peninsular Malaysia by Subramaniam, V., Thevanayagam, H.

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Topology optimization of conductive heat transfer devices: An experimental investigation by Subramaniam, V., Dbouk, T., Harion, J.-L.

“…•Experimental thermal measurements of optimal heat sinks.•Experimental heat sinks obtained by topology optimization.•Bi-material distribution in…”
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Clinical outcomes of xeno-free autologous cultivated limbal epithelial transplantation: a 10-year study by Sangwan, Virender S, Basu, Sayan, Vemuganti, Geeta K, Sejpal, Kunjal, Subramaniam, Sandhya V, Bandyopadhyay, Souvik, Krishnaiah, Sannapaneni, Gaddipati, Subhash, Tiwari, Shubha, Balasubramanian, Dorairajan

“…Ocular burns can damage the corneal epithelial stem cells located at the limbus. This study evaluated the efficacy of xeno-free autologous cell-based treatment…”
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Blast Furnace Slag Hydration in an Alkaline Medium: Influence of Sodium Content and Sodium Hydroxide Molarity by Reddy, K. Chiranjeevi, Subramaniam, Kolluru V. L

“…AbstractThe reaction of blast furnace slag in sodium hydroxide (NaOH) solutions of different molarities is evaluated. The compressive strength of the activated…”
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Fracture in 3D-Printed Concrete Beams: Deflection and Penetration of Impinging Cracks at Layer Interfaces by Subramaniam, Kolluru V. L., Paritala, Spandana, Kulkarni, Omkar, Thakur, Manideep S.

“…AbstractStructural assemblies produced using three-dimensional (3D) concrete printing consist of multiple layers of extruded material deposited along precise…”
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Evidence for dimerization of ferroportin in a human hepatic cell line using proximity ligation assays by Rishi, Gautam, Secondes, Eriza S, Wallace, Daniel F, Subramaniam, V Nathan

“…Mutations in the only known iron exporter ferroportin (FPN) in humans are associated with the autosomal dominantly inherited iron overload disorder ferroportin…”
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Direct determination of cohesive stress transfer during debonding of FRP from concrete by Carloni, Christian, Subramaniam, Kolluru V.

“…Interface cohesive stress transfer between FRP and concrete during debonding is typically obtained using measured surface strains on the FRP, along the…”
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The potential prognostic utility of salivary galectin-3 concentrations in heart failure by Zhang, Xi, Karunathilaka, Nuwan, Senanayake, Sameera, Subramaniam, V. Nathan, Chan, Wandy, Kostner, Karam, Fraser, John, Atherton, John J., Punyadeera, Chamindie

“…Background Patients with HF are at a higher risk of rehospitalisation and, as such, significant costs to our healthcare system. A non-invasive method to…”
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