Search Results - "Subhashini, N"
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Design and synthesis of imidazolo-1, 2,3-triazoles hybrid compounds by microwave-assisted method: Evaluation as an antioxidant and antimicrobial agents and molecular docking studies
Published in Journal of molecular structure (15-03-2019)“…The present manuscript describes synthesis of a new class of antimicrobial and antioxidant agents (imidazole linked 1,2,3-triazole hybrid compounds) and…”
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2
Design and synthesis of novel (Z)-5-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)-3-((1-substituted phenyl-1H-1,2,3-triazol-4-yl)methyl)thiazolidine-2,4-diones: a potential cytotoxic scaffolds and their molecular modeling studies
Published in Molecular diversity (01-11-2021)“…In an effort to discover potential cytotoxic agents, a series of novel ( Z )-5-((1,3-diphenyl-1 H -pyrazol-4-yl)methylene)-3-((1-substituted phenyl-1 H…”
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3
Design, synthesis of novel (Z)-2-(3-(4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)methyl)-1-phenyl-1H-pyrazol-3-yl)phenoxy)-N-arylacetamide derivatives: Evaluation of cytotoxic activity and molecular docking studies
Published in Journal of molecular structure (15-02-2020)“…In an attempt to discover potential cytotoxic agents, a series of novel (Z)-2-(3-(4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)methyl)-1-phenyl-1H-pyrazol-3-yl)…”
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4
Selective CDK4/6 inhibition of novel 1,2,3-triazole tethered acridinedione derivatives induces G1/S cell cycle transition arrest via Rb phosphorylation blockade in breast cancer models
Published in Bioorganic chemistry (01-11-2021)“…[Display omitted] •Novel series of 1,2,3-triazole tethered acridinedione derivatives were synthesized based on structured based design.•Among the series,…”
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5
Design, Synthesis, Anticancer Evaluation, and Molecular Docking Studies of Novel Benzoxazole Linked 1,3,4-Oxadiazoles
Published in Anti-cancer agents in medicinal chemistry (01-03-2022)“…Cancer disease is a serious concern globally. Global cancer occurrence is steadily increasing every year. There is always a persistent need to develop new…”
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6
Cu(II) complexes with 4-amino-3,5-dimethyl isoxazole and substituted aromatic aldehyde Schiff bases: synthesis, crystal structure, antimicrobial activity, DNA binding and cleavage studies
Published in Journal of coordination chemistry (18-04-2017)“…Three isoxazole Schiff bases 2-((E)-(3,5-dimethylisoxazol-4-ylimino)methyl)-6-methoxyphenol (L 1 ),…”
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7
Synthesis, anti-diabetic evaluation and molecular docking studies of 4-(1-aryl-1H-1, 2, 3-triazol-4-yl)-1,4-dihydropyridine derivatives as novel 11-β hydroxysteroid dehydrogenase-1 (11β-HSD1) inhibitors
Published in Bioorganic chemistry (01-09-2019)“…[Display omitted] •A series of novel 1,4-dihydropyridine tethered to triazole ring were synthesized.•These are evaluated in-vitro and in-vivo to inhibit…”
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8
Syk – GTP RAC-1 mediated immune-stimulatory effect of Cuscuta epithymum, Ipomoea batata and Euphorbia hirta plant extracts
Published in Biomedicine & pharmacotherapy (01-12-2017)“…[Display omitted] •Methanolic extracts of the study plants stimulated phagocytosis comparable to standard.•Syk – GTP RAC-1 mediates the immune-stimulatory…”
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Design, synthesis of (Z)‐3‐benzyl‐5‐((1‐phenyl‐3‐(3‐((1‐ substituted phenyl‐1H‐1,2,3‐triazol‐4‐yl)methoxy)phenyl)‐1H‐pyrazol‐4‐yl)methylene)thiazolidine‐2,4‐dione analogues as potential cytotoxic agents
Published in Journal of heterocyclic chemistry (01-12-2019)“…In an attempt to achieve promising cytotoxic agents, a series of new (Z)‐3‐benzyl‐5‐((1‐phenyl‐3‐(3‐((1‐substituted…”
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10
Synthesis and anti-inflammatory activity of some novel 3-phenyl-N-[3-(4-phenylpiperazin-1yl)propyl]-1H-pyrazole-5-carboxamide derivatives
Published in Bioorganic & medicinal chemistry letters (15-07-2011)“…A new series of 3-phenyl-N-[3-(4-phenylpiperazin-1yl)propyl]-1H-pyrazole-5-carboxamide derivatives were synthesized and investigated their anti-inflammatory…”
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11
Novel Benzosuberone-quinazolinone Derivatives: Synthesis and Antitumour Activity
Published in Russian journal of general chemistry (01-10-2020)“…Novel benzosuberone-quinazolinones hybrids have been synthesized efficiently in high yields, and their structures have been confirmed by 1 H and 13 C NMR,…”
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12
Synthesis of novel isoindolone‐based medium‐sized macromolecules and triazole containing heterocyclic compounds
Published in Journal of heterocyclic chemistry (01-12-2019)“…A series of novel isoindolone‐based macromolecules of medium‐sized heterocyclic rings, such as…”
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13
Synthesis and Antimicrobial Activity of Novel Bis-1,2,3-triazol-1H-4-yl-substituted Aryl Benzimidazole-2-thiol Derivatives
Published in Russian journal of general chemistry (01-08-2020)“…Novel bis-1,2,3-triazol-1 H -4-yl-substituted aryl benzimidazole-2-thiol derivatives have been synthesized from 5-methoxy and 5-difluoromethoxy bis-propargyl…”
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14
Synthesis, potentiometric and antimicrobial studies on metal complexes of isoxazole Schiff bases
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (01-06-2008)“…The metal complexes of Cu(II), Ni(II) and Co(II) with Schiff bases of 3-(2-hydroxy-3-ethoxybenzylideneamino)-5-methyl isoxazole [HEBMI] and…”
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15
Total synthesis of patulolide A through ring closing metathesis
Published in Synthetic communications (04-03-2018)“…A simple and efficient total synthesis of patulolide A from readily available 7-octen-1-ol is reported by asymmetric synthetic approach. The key reactions…”
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16
Factors affecting clinical experience of nursing students in Malaysia: A cross-sectional study
Published in Journal of education and health promotion (01-10-2024)“…BACKGROUND: Nursing education covers pathophysiology, nursing procedures, and compassionate care. Nursing students can apply theory and develop skills in the…”
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Synthesis, anticancer activity and docking studies of N-phenyl-2-(2-((4-phenyl piperazin-1-yl) methyl)-1H-benzo [d] imidazol-1-yl) acetamides
Published in Journal of molecular structure (15-08-2018)“…A series of novel N-phenyl-2-(2-((4-phenyl piperazin-1-yl) methyl)-1H-benzo [d] imidazol-1-yl) acetamides (7a-o) have been synthesized in multiple steps with…”
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18
Involvement of the α1-adrenoceptor in sleep–waking and sleep loss-induced anxiety behavior in zebrafish
Published in Neuroscience (15-08-2013)“…Highlights • Zebrafish sleep–wake cycles show a diurnal rhythm. • Constant light exposure deprives the fish of sleep. • Place preferences in fish sleep are…”
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19
Effect of blended self-directed learning on nursing students: Quasi-experimental approach
Published in Journal of Education and Health Promotion (01-01-2023)“…BACKGROUND: Higher education institutions are adapting and innovating like never before to provide highly individualized learning environments for both…”
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20
Synthesis of hydrazone derivatives of benzofuran and their antibacterial and antifungal activity
Published in Russian journal of general chemistry (01-09-2017)“…A series of benzofuran hydrazones 6a – 6n were synthesized from benzofuran aldehyde and substituted aromatic hydrazides 5a – 5n . Structures of all compounds…”
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