Search Results - "Suberi, Alexandra"

Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses by Mao, Tianyang, Israelow, Benjamin, Peña-Hernández, Mario A, Suberi, Alexandra, Zhou, Liqun, Luyten, Sophia, Reschke, Melanie, Dong, Huiping, Homer, Robert J, Saltzman, W Mark, Iwasaki, Akiko

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has highlighted the need for vaccines that not only prevent disease but also prevent…”
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PEGylation of poly(amine-co-ester) polyplexes for tunable gene delivery by Grun, Molly K., Suberi, Alexandra, Shin, Kwangsoo, Lee, Teresa, Gomerdinger, Victoria, Moscato, Zoe M., Piotrowski-Daspit, Alexandra S., Saltzman, W. Mark

“…There is growing interest in PEGylation of cationic polymeric vehicles for gene delivery in order to improve vehicle stability and reduce toxicity, but little…”
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Branching in poly(amine-co-ester) polyplexes impacts mRNA transfection by Shin, Kwangsoo, Suh, Hee-Won, Suberi, Alexandra, Whang, Chang-Hee, Ene, Madalina, Grundler, Julian, Grun, Molly K., Saltzman, W. Mark

“…Branching is a key structural parameter of polymers, which can have profound impacts on physicochemical properties. It has been demonstrated that branching is…”
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Polymer nanoparticles deliver mRNA to the lung for mucosal vaccination by Suberi, Alexandra, Grun, Molly K, Mao, Tianyang, Israelow, Benjamin, Reschke, Melanie, Grundler, Julian, Akhtar, Laiba, Lee, Teresa, Shin, Kwangsoo, Piotrowski-Daspit, Alexandra S, Homer, Robert J, Iwasaki, Akiko, Suh, Hee-Won, Saltzman, W Mark

“…An inhalable platform for messenger RNA (mRNA) therapeutics would enable minimally invasive and lung-targeted delivery for a host of pulmonary diseases…”
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Subcellular topography modulates actin dynamics and signaling in B-cells by Ketchum, Christina M, Sun, Xiaoyu, Suberi, Alexandra, Fourkas, John T, Song, Wenxia, Upadhyaya, Arpita

“…B-cell signaling activation is most effectively triggered by the binding of B-cell receptors (BCRs) to membrane-bound antigens. In vivo, B-cells encounter…”
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Pulmonary Delivery of mRNA Therapeutics by Suberi, Alexandra A

“…Advances in mRNA sequence design and chemical modifications have brought us to the precipice of translating mRNA therapeutics to treat and cure innumerable…”
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Topography on a subcellular scale modulates cellular adhesions and actin stress fiber dynamics in tumor associated fibroblasts by Azatov, Mikheil, Sun, Xiaoyu, Suberi, Alexandra, Fourkas, John T, Upadhyaya, Arpita

“…Cells can sense and adapt to mechanical properties of their environment. The local geometry of the extracellular matrix, such as its topography, has been shown…”
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