Search Results - "Subbulakshmi, Venkita"

Optimization of Pyrrolamides as Mycobacterial GyrB ATPase Inhibitors: Structure-Activity Relationship and In Vivo Efficacy in a Mouse Model of Tuberculosis by SHAHUL HAMEED, P, SOLAPURE, Suresh, GHOSH, Anirban, AWASTHY, Disha, SHANBHAG, Gajanan, SHEIKH, Gulebahar, MCMIKEN, Helen, PUTTUR, Jayashree, REDDY, Jitendar, WERNGREN, Jim, READ, Jon, KUMAR, Mahesh, MUKHERJEE, Kakoli, MANJUNATHA, R, CHINNAPATTU, Murugan, MADHAVAPEDDI, Prashanti, MANJREKAR, Praveena, BASU, Reetobrata, GAONKAR, Sheshagiri, SHARMA, Sreevalli, HOFFNER, Sven, HUMNABADKAR, Vaishali, SUBBULAKSHMI, Venkita, NANDI, Vrinda, PANDUGA, Vijender, WATERSON, David, SHANDIL, Radha, BALGANESH, Meenakshi, SAMBANDAMURTHY, Vasan K, ANAND KUMAR RAICHURKAR, DESHPANDE, Abhijeet

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Essentiality and functional analysis of type I and type III pantothenate kinases of Mycobacterium tuberculosis by AWASTHY, Disha, AMBADY, Anisha, BHAT, Jyothi, SHEIKH, Gulebahar, RAVISHANKAR, Sudha, SUBBULAKSHMI, Venkita, MUKHERJEE, Kakoli, SAMBANDAMURTHY, Vasan, SHARMA, Umender

“…Pantothenate kinase, an essential enzyme in bacteria and eukaryotes, is involved in catalysing the first step of conversion of pantothenate to coenzyme A…”
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Alanine racemase mutants of Mycobacterium tuberculosis require D-alanine for growth and are defective for survival in macrophages and mice by AWASTHY, Disha, BHARATH, Sowmya, SUBBULAKSHMI, Venkita, SHARMA, Umender

“…Alanine racemase (Alr) is an essential enzyme in most bacteria; however, some species (e.g. Listeria monocytogenes) can utilize d-amino acid transaminase (Dat)…”
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Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure–activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-d-ribose 2′-oxidase by Landge, Sudhir, Mullick, Amrita B., Nagalapur, Kavitha, Neres, João, Subbulakshmi, Venkita, Murugan, Kannan, Ghosh, Anirban, Sadler, Claire, Fellows, Mick D., Humnabadkar, Vaishali, Mahadevaswamy, Jyothi, Vachaspati, Prakash, Sharma, Sreevalli, Kaur, Parvinder, Mallya, Meenakshi, Rudrapatna, Suresh, Awasthy, Disha, Sambandamurthy, Vasan K., Pojer, Florence, Cole, Stewart T., Balganesh, Tanjore S., Ugarkar, Bheemarao G., Balasubramanian, V., Bandodkar, Balachandra S., Panda, Manoranjan, Ramachandran, Vasanthi

“…[Display omitted] We report the discovery of benzothiazoles, a novel anti-mycobacterial series, identified from a whole cell based screening campaign…”
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Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice by Awasthy, Disha, Gaonkar, Sheshagiri, Shandil, R. K, Yadav, Reena, Bharath, Sowmya, Marcel, Nimi, Subbulakshmi, Venkita, Sharma, Umender

“…AstraZeneca R&D, Bellary Road, Hebbal, Bangalore-560024, India Acetohydroxyacid synthase (AHAS) is the first enzyme in the branched-chain amino acid…”
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Optimization of Pyrrolamides as Mycobacterial GyrB ATPase Inhibitors: Structure-Activity Relationship and In Vivo Efficacy in a Mouse Model of Tuberculosis by P, Shahul Hameed, Solapure, Suresh, Mukherjee, Kakoli, Nandi, Vrinda, Waterson, David, Shandil, Radha, Balganesh, Meenakshi, Sambandamurthy, Vasan K, Raichurkar, Anand Kumar, Deshpande, Abhijeet, Ghosh, Anirban, Awasthy, Disha, Shanbhag, Gajanan, Sheikh, Gulebahar, McMiken, Helen, Puttur, Jayashree, Reddy, Jitendar, Werngren, Jim, Read, Jon, Kumar, Mahesh, R, Manjunatha, Chinnapattu, Murugan, Madhavapeddi, Prashanti, Manjrekar, Praveena, Basu, Reetobrata, Gaonkar, Sheshagiri, Sharma, Sreevalli, Hoffner, Sven, Humnabadkar, Vaishali, Subbulakshmi, Venkita, Panduga, Vijender

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PKCα regulates phosphorylation and enzymatic activity of cPLA2 in vitro and in activated human monocytes by Li, Qing, Subbulakshmi, Venkita, Oldfield, Claudine M., Aamir, Rozina, Weyman, Crystal M., Wolfman, Alan, Cathcart, Martha K.

“…Phospholipases A2 (PLA2) are potent regulators of the inflammatory response. We have observed that Group IV cPLA2 activity is required for the production of…”
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PKCalpha regulates phosphorylation and enzymatic activity of cPLA2 in vitro and in activated human monocytes by Li, Qing, Subbulakshmi, Venkita, Oldfield, Claudine M, Aamir, Rozina, Weyman, Crystal M, Wolfman, Alan, Cathcart, Martha K

“…Phospholipases A(2) (PLA(2)) are potent regulators of the inflammatory response. We have observed that Group IV cPLA(2) activity is required for the production…”
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PKCα regulates phosphorylation and enzymatic activity of cPLA 2 in vitro and in activated human monocytes by Li, Qing, Subbulakshmi, Venkita, Oldfield, Claudine M., Aamir, Rozina, Weyman, Crystal M., Wolfman, Alan, Cathcart, Martha K.

“…Phospholipases A 2 (PLA 2) are potent regulators of the inflammatory response. We have observed that Group IV cPLA 2 activity is required for the production of…”
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Protein kinase C delta is required for p47phox phosphorylation and translocation in activated human monocytes by Bey, Erik A, Xu, Bo, Bhattacharjee, Ashish, Oldfield, Claudine M, Zhao, Xiaoxian, Li, Qing, Subbulakshmi, Venkita, Feldman, Gerald M, Wientjes, Frans B, Cathcart, Martha K

“…Our laboratory is interested in understanding the regulation of NADPH oxidase activity in human monocyte/macrophages. Protein kinase C (PKC) is reported to be…”
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Protein Kinase C delta Is Required for p47 super(phox) Phosphorylation and Translocation in Activated Human Monocytes by Bey, Erik A, Xu, Bo, Bhattacharjee, Ashish, Oldfield, Claudine M, Zhao, Xiaoxian, Li, Qing, Subbulakshmi, Venkita, Feldman, Gerald M, Wientjes, Frans B, Cathcart, Martha K

“…Our laboratory is interested in understanding the regulation of NADPH oxidase activity in human monocyte/macrophages. Protein kinase C (PKC) is reported to be…”
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Protein Kinase Cδ Is Required for p47 phox Phosphorylation and Translocation in Activated Human Monocytes by Bey, Erik A., Xu, Bo, Bhattacharjee, Ashish, Oldfield, Claudine M., Zhao, Xiaoxian, Li, Qing, Subbulakshmi, Venkita, Feldman, Gerald M., Wientjes, Frans B., Cathcart, Martha K.

“…Our laboratory is interested in understanding the regulation of NADPH oxidase activity in human monocyte/macrophages. Protein kinase C (PKC) is reported to be…”
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Protein Kinase Cα Regulates Human Monocyte O·̄2Production and Low Density Lipoprotein Lipid Oxidation by Li, Qing, Subbulakshmi, Venkita, Fields, Alan P., Murray, Nicole R., Cathcart, Martha K.

“…Our previous studies have shown that human native low density lipoprotein (LDL) can be oxidized by activated human monocytes. In this process, both activation…”
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Protein Kinase Cα Regulates Human Monocyte O·̄2Production and Low Density Lipoprotein Lipid Oxidation by Qing Li, Venkita Subbulakshmi, Alan P. Fields, Nicole R. Murray, Martha K. Cathcart

“…Our previous studies have shown that human native low density lipoprotein (LDL) can be oxidized by activated human monocytes. In this process, both activation…”
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Mechanism of Protein A-Induced Amelioration of Toxicity of Anti-AIDS Drug, Zidovudine by Subbulakshmi, Venkita, Ghosh, Amiya K., Das, Tanya, Ray, Prasanta K.

“…Long-term treatment with 3-azido-3-deoxy thymidine (AZT) is often associated with myelosuppression. In AZT-treated Swiss mice, similar toxicological…”
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Protein Kinase C{delta} Is Required for p47phox Phosphorylation and Translocation in Activated Human Monocytes by Bey, Erik A, Xu, Bo, Bhattacharjee, Ashish, Oldfield, Claudine M, Zhao, Xiaoxian, Li, Qing, Subbulakshmi, Venkita, Feldman, Gerald M, Wientjes, Frans B, Cathcart, Martha K

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